未登录Discovery of MK-3168: A PET Tracer for Imaging Brain Fatty Acid Amide HydrolaseMK-3168的发现: 用于脑脂肪酸酰胺水解酶成像的PET示踪剂
Liu, Ping; Hamill, Terence G.; Chioda, Marc; Chobanian, Harry; Fung, Selena; Guo, Yan; Chang, Linda; Bakshi, Raman; Hong, Qingmei; Dellureficio, James; Lin, Linus S.; Abbadie, Catherine; Alexander, Jessica; Jin, Hong; Mandala, Suzanne; Shiao, Lin-Lin; Li, Wenping; Sanabria, Sandra; Williams, David; Zeng, Zhizhen; Hajdu, Richard; Jochnowitz, Nina; Rosenbach, Mark; Karanam, Bindhu; Madeira, Maria; Salituro, Gino; Powell, Joyce; Xu, Ling; Terebetsld, Jenna L.; Leone, Joseph F.; Miller, Patricia; Cook, Jacquelynn; Holahan, Marie; Joshi, Aniket; O'Malley, Stacey; Purcell, Mona; Posavec, Diane; Chen, Tsing-Bau; Riffe, Kerry; Williams, Mangay; Hargreaves, Richard; Sullivan, Kathleen A.; Nargund, Ravi P.; DeVitat, Robert J.
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收藏Design, synthesis, and in vivo efficacy of glycine transporter-1 (GlyT1) inhibitors derived from a series of [4-phenyl-1(propylsulfonyl)piperidin-4-yl]lmethyl benzamides
Lindsley, Craig W.; Zhao, Zhijian; Leister, William H.; O'Brien, Julie; Lemaire, Wei; Williams, David L., Jr.; Chen, Tsing-Bau; Chang, Raymond S. L.; Burno, Maryann; Jacobson, Marlene A.; Sur, Cyrille; Kinney, Gene G.; Pettibone, Douglas J.; Tiller, Philip R.; Smith, Sheri; Tsou, Nancy N.; Duggan, Mark E.; Conn, P. Jeffrey; Hartman, George D.
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收藏Difference in mGluR5 interaction between positive allosteric modulators from two structural classes来自两个结构课程的正变构调节剂之间mGluR5相互作用的差异
Williams, DL; O'Brien, JA; Lemaire, W; Chen, TB; Chang, RSL; Jacobson, MA; Ha, SN; Wisnoski, DD; Lindsley, CW; Sur, C; Duggan, ME; Pettibone, DJ; Conn, PJ
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收藏A novel selective positive allosteric modulator of metabotropic glutamate receptor subtype 5 has in vivo activity and antipsychotic-like effects in rat behavioral models
Kinney, GG; O'Brien, JA; Lemaire, W; Burno, M; Bickel, DJ; Clements, MK; Chen, TB; Wisnoski, DD; Lindsley, CW; Tiller, PR; Smith, S; Jacobson, MA; Sur, C; Duggan, ME; Pettibone, DJ; Conn, PJ; Williams, DL
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收藏Generation and characterization of a human bradykinin receptor B1 transgenic rat as a pharmacodynamic model
Hess, JF; Ransom, RW; Zeng, ZZ; Chang, RSL; Hey, PJ; Warren, L; Harrell, CM; Murphy, KL; Chen, TB; Miller, PJ; Lis, E; Reiss, D; Gibson, RE; Markowitz, MK; DiPardo, RM; Su, DS; Bock, MG; Gould, RJ; Pettibone, DJ
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收藏A family of highly selective allosteric modulators of the metabotropic glutamate receptor subtype 5
O'Brien, JA; Lemaire, W; Chen, TB; Chang, RSL; Jacobson, MA; Ha, SN; Lindsley, CW; Schaffhauser, HJ; Sur, C; Pettibone, DJ; Conn, PJ; Williams, DL
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收藏Benzodiazepines as potent and selective bradykinin B1 antagonists
Wood, MR; Kim, JJ; Han, W; Dorsey, BD; Homnick, CF; DiPardo, RM; Kuduk, SD; MacNeil, T; Murphy, KL; Lis, EV; Ransom, RW; Stump, GL; Lynch, JJ; O'Malley, SS; Miller, PJ; Chen, TB; Harrell, CM; Chang, RSL; Sandhu, P; Ellis, JD; Bondiskey, PJ; Pettibone, DJ; Freidinger, RM; Bock, MG
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收藏A HIGHLY POTENT, ORALLY-ACTIVE IMIDAZO[4,5-B]PYRIDINE BIPHENYLACYLSULFONAMIDE (MK-996-L-159,282) - A NEW ANGIOTENSIN-II RECEPTOR ANTAGONIST
CHAKRAVARTY, PK; NAYLOR, EM; CHEN, A; CHANG, RSL; CHEN, TB; FAUST, KA; LOTTI, VJ; KIVLIGHN, SD; GABLE, RA; ZINGARO, GJ; SCHORN, TW; SCHAFFER, LW; BROTEN, TP; SIEGL, PKS; PATCHETT, AA; GREENLEE, WJ
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收藏TRIAZOLINONE BIPHENYLSULFONAMIDE DERIVATIVES AS ORALLY-ACTIVE ANGIOTENSIN-II ANTAGONISTS WITH POTENT AT(1) RECEPTOR AFFINITY AND ENHANCED AT(2) AFFINITY
ASHTON, WT; CHANG, LL; FLANAGAN, KL; HUTCHINS, SM; NAYLOR, EM; CHAKRAVARTY, PK; PATCHETT, AA; GREENLEE, WJ; CHEN, TB; FAUST, KA; CHANG, RSL; LOTTI, VJ; ZINGARO, GJ; SCHORN, TW; SIEGL, PKS; KIVLIGHN, SD
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