未登录 Gold-containing compounds target an apicomplexan Thioredoxin reductase: Disclosing reactivity through structural and functional characterization 含金化合物靶向顶复门硫氧还蛋白还原酶：通过结构和功能表征揭示反应性 Gabriele, Federica; Palerma, Marta; Bogard, Jala; Paluzzi, Luca; Zineddu, Stefano; Geri, Andrea; Vitali, Valentina; Massai, Lara; Ardini, Matteo; Bellelli, Andrea; Petukhov, Pavel A.; Ippoliti, Rodolfo; Messori, Luigi; Williams, David L.; Angelucci, Francesco 分享 收藏
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Amyloidogenesis promotes HSF1 activity enhancing cell survival during breast cancer metastatic colonization 淀粉样蛋白生成促进HSF1活性，增强细胞在乳腺癌转移性定植期间的存活能力。 Hockaden, Natasha; Leriger, Gabi; Wang, John; Ray, Haimanti; Chakrabarti, Sunandan; Downing, Nicholas; Desmond, Jacob; Williams, David; Hollenhorst, Peter C.; Longmore, Gregory; Carpenter, Richard L. 分享 收藏
Targeting Apicomplexan Parasites: Structural and Functional Characterization of Cryptosporidium Thioredoxin Reductase as a Novel Drug Target 靶向顶复门寄生虫：隐孢子虫硫氧还蛋白还原酶的结构与功能特征作为新型药物靶点 Gabriele, Federica; Bogard, Jala A.; Palerma, Marta; Ardini, Matteo; Byrne, Margaret E.; Chen, Xian-Ming; Petukhov, Pavel A.; Ippoliti, Rodolfo; Angelucci, Francesco; Williams, David L. 分享 收藏
Pleiotropic anti-cancer activities of novel non-covalent thioredoxin reductase inhibitors against triple negative breast cancer Flowers, Brenna; Rullo, Abigail; Zhang, An; Chang, Keacha; Petukhova, Valentina Z.; Aboagye, Sammy Y.; Angelucci, Francesco; Williams, David L.; Kregel, Steven; Petukhov, Pavel A.; Kastrati, Irida 分享 收藏
Regioselective Synthesis of Potential Non-Quinonoid Prodrugs of Plasmodione: Antiparasitic Properties Against Two Hemoglobin-Feeding Parasites and Drug Metabolism Studies Cesar-Rodo, Elena; Dupouy, Baptiste; Haberli, Cecile; Strub, Jean-Marc; Williams, David L.; Maser, Pascal; Rottmann, Matthias; Keiser, Jennifer; Lanfranchi, Don Antoine; Davioud-Charvet, Elisabeth 分享 收藏
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Non-covalent inhibitors of thioredoxin glutathione reductase with schistosomicidal activity in vivo 具有体内杀血吸虫活性的硫氧还蛋白谷胱甘肽还原酶的非共价抑制剂 Petukhova, Valentina Z.; Aboagye, Sammy Y.; Ardini, Matteo; Lullo, Rachel P.; Fata, Francesca; Byrne, Margaret E.; Gabriele, Federica; Martin, Lucy M.; Harding, Luke N. M.; Gone, Vamshikrishna; Dangi, Bikash; Lantvit, Daniel D.; Nikolic, Dejan; Ippoliti, Rodolfo; Effantin, Gregory; Ling, Wai Li; Johnson, Jeremy J.; Thatcher, Gregory R. J.; Angelucci, Francesco; Williams, David L.; Petukhov, Pavel A. 分享 收藏
A Hybrid of Amodiaquine and Primaquine Linked by Gold(I) Is a Multistage Antimalarial Agent Targeting Heme Detoxification and Thiol Redox Homeostasis 由金 (I) 连接的阿莫迪喹和Primaquine的混合体是一种针对血红素解毒和硫醇氧化还原稳态的多级抗疟药 Pereira, Caroline De Souza; Quadros, Helenita Costa; Aboagye, Samuel Yaw; Fontinha, Diana; D'Alessandro, Sarah; Byrne, Margaret Elizabeth; Gendrot, Mathieu; Fonta, Isabelle; Mosnier, Joel; Moreira, Diogo Rodrigo M.; Basilico, Nicoletta; Williams, David. L. L.; Prudencio, Miguel; Pradines, Bruno; Navarro, Maribel 分享 收藏
Role Of The Antiapoptotic C-iap2 On The Generation Of An Endothelial Memory In Schistosomiasis-associated Pulmonary Arterial Hypertension Oliveira, Suellen Darc; Erewele, Ejehi; Castellon, Maricela; Schwartz, Andrew; Williams, David L.; Morrell, Nick; Bonini, Marcelo; Silva, Claudia L. M.; Lutz, Sarah E.; Erzurum, Serpil; Minshall, Richard D. 分享 收藏
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Probing the Surface of a Parasite Drug Target Thioredoxin Glutathione Reductase Using Small Molecule Fragments 使用小分子片段探测寄生虫药物靶向硫氧还蛋白谷胱甘肽还原酶的表面 Fata, Francesca; Silvestri, Ilaria; Ardini, Matteo; Ippoliti, Rodolfo; Di Leandro, Luana; Demitri, Nicola; Polentarutti, Maurizio; Di Matteo, Adele; Lyu, Haining; Thatcher, Gregory R. J.; Petukhov, Pavel A.; Williams, David L.; Angelucci, Francesco 分享 收藏
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Repurposing Auranofin and Evaluation of a New Gold(I) Compound for the Search of Treatment of Human and Cattle Parasitic Diseases: From Protozoa to Helminth Infections Feng, Liwen; Pomel, Sebastien; de Late, Perle Latre; Taravaud, Alexandre; Loiseau, Philippe M.; Maes, Louis; Cho-Ngwa, Fidelis; Bulman, Christina A.; Fischer, Chelsea; Sakanari, Judy A.; Ziniel, Peter D.; Williams, David L.; Davioud-Charvet, Elisabeth 分享 收藏
Bioelution, Bioavailability, and Toxicity of Cobalt Compounds Correlate (vol 174, pg 311, 2020) Danzeisen, Ruth; Williams, David Lee; Viegas, Vanessa; Dourson, Michael; Verberckmoes, Steven; Burzlaff, Arne 分享 收藏
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