Carmen Fernández‐Metzler

rutgers university new brunswick

18H指数

53论文数

2.2K被引数

收录论文 10

发表时间

Why is Biomarker Assay Validation Different from that of Pharmacokinetic Assays?为什么生物标志物检定与药代动力学检定不同？

The AAPS Journal

IF0

2025-09-30

PREAI

Yan G. Ni; Lauren F. Stevenson; Lakshmi Amaravadi; Carmen Fernández-Metzler; Lindsay King; Steven P. Piccoli; Amanda Hays; Dhiman Ghosh; Sarah Mitchell Bean; Stephanie Cape; Enrique A. Dalmasso; Shashank Gorityala; Jennifer Green; Michele Gunsior; Mohamed Hassanein; Sreenivas Laxmanan; Robert J. Neely; Alok Pandey; Xiazi Qiu; Chunyan Tinder; Jianing Zeng; Jad Zoghbi; Karen J. Quadrini

Best Practices and Recommendations for Non-Liquid Matrices Bioanalysis

AAPS JOURNAL

IF3.7

2025-03-11

OAAI

Vazvaei-Smith, Faye; Li, Wenkui; Barnaby, Omar S.; Bhardwaj, Sanjeev; Dong, Juyao; Dumont, Carolyne; Fernandez-Metzler, Carmen; Geist, Brian; Hassanein, Mohamed; Hays, Amanda; Ilinskaya, Anna; Kadar, Eugene P.; King, Kris; Kulagina, Nadia; Matta, Murali K.; Midde, Krishna; Pan, Rina; Pathania, Divya; Tarnowski, Thomas; Tewalt, Eric; Thomas, Eric; Wickremsinhe, Enaksha; Xiao, Deqing

Biomarker Assay Validation by Mass Spectrometry

AAPS JOURNAL

IF3.7

2022-05-09

OAAI

Fernandez-Metzler, Carmen; Ackermann, Brad; Garofolo, Fabio; Arnold, Mark E.; DeSilva, Binodh; Gu, Huidong; Laterza, Omar; Mao, Yan; Rose, Mark; Vazvaei-Smith, Faye; Steenwyk, Rick

Is Incurred Sample Reanalysis (ISR) Applicable in Biomarker Assays?

AAPS JOURNAL

IF3.7

2022-05-05

PREAI

Hays, Amanda; Amaravadi, Lakshmi; Fernandez-Metzler, Carmen; King, Lindsay; Mathews, Joel; Ni, Yan; Quadrini, Karen; Tinder, Chunyan; Vazvaei, Faye; Zeng, Jianing

Riluzole prodrugs for melanoma and ALS: Design, synthesis, and in vitro metabolic profiling 用于黑色素瘤和ALS的利鲁唑前药: 设计，合成和体外代谢分析

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2012-09-01

OAAI

McDonnell, Mark E.; Vera, Matthew D.; Blass, Benjamin E.; Pelletier, Jeffrey C.; King, Richard C.; Fernandez-Metzler, Carmen; Smith, Garry R.; Wrobel, Jay; Chen, Suzie; Wall, Brian A.; Reitz, Allen B.

Routine micro-sampling and LC-MS/MS quantitation for PK and PK/PD determination in mice

CANCER RESEARCH

IF16.6

2012-04-01

PREAI

Fernandez-Metzler, Carmen; King, Richard C.; Wilson, Denielle; Machin, Amanda; Otto, Todd; Franklin, Marshall

Kinesin spindle protein (KSP) inhibitors.: 9.: Discovery of (2S)-4-(2,5-difluorophenyl)-N-[(3R,4S)-3-fluoro-1-methylpiperidin-4-yl]-2-(hydroxymethyl)-N-methyl-2-phenyl-2,5-dihydro-1H-pyrrole-1-carboxamide (MK-0731) for the treatment of taxane-refractory cancer

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2008-06-25

154

PREAI

Cox, Christopher D.; Coleman, Paul J.; Breslin, Michael J.; Whitman, David B.; Garbaccio, Robert M.; Fraley, Mark E.; Buser, Carolyn A.; Walsh, Eileen S.; Hamilton, Kelly; Schaber, Michael D.; Lobell, Robert B.; Tao, Weikang; Davide, Joseph P.; Diehl, Ronald E.; Abrams, Marc T.; South, Vicki J.; Huber, Hans E.; Torrent, Maricel; Prueksaritanont, Thomayant; Li, Chunze; Slaughter, Donald E.; Mahan, Elizabeth; Fernandez-Metzler, Carmen; Yan, Youwei; Kuo, Lawrence C.; Kohl, Nancy E.; Hartman, George D.

Nonpeptide αvβ3 antagonists.: Part 11:: Discovery and preclinical evaluation of potent αvβ3 antagonists for the prevention and treatment of osteoporosis

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2004-08-26

PREAI

Coleman, PJ; Brashear, KM; Askew, BC; Hutchinson, JH; McVean, CA; Duong, LT; Feuston, BP; Fernandez-Metzler, C; Gentile, MA; Hartman, GD; Kimmel, DB; Leu, CT; Lipfert, L; Merkle, K; Pennypacker, B; Prueksaritanont, T; Rodan, GA; Wesolowski, GA; Rodan, SB; Duggan, ME

Nonpeptide αvβ3 antagonists.: 8.: In vitro and in vivo evaluation of a potent αvβ3 antagonist for the prevention and treatment of osteoporosis

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2003-09-27

PREAI

Hutchinson, JH; Hatczenko, W; Brashear, KM; Breslin, MJ; Coleman, PJ; Duong, LT; Fernandez-Metzler, C; Gentile, MA; Fisher, JE; Hartman, GD; Huff, JR; Kimmel, DB; Leu, CT; Meissner, RS; Merkle, K; Nagy, R; Pennypacker, B; Perkins, JJ; Prueksaritanont, T; Rodan, GA; Varga, SL; Wesolowski, GA; Zartman, AE; Rodan, SB; Duggan, ME

Mechanistic investigation of ionization suppression in electrospray ionization

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

IF2.7

2000-11-01

1.1K

PREAI

King, R; Bonfiglio, R; Fernandez-Metzler, C; Miller-Stein, C; Olah, T

研究方向