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P

Pascal Marchand

Nantes Universite
H指数:20
被引数:1,312

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Pharmacophore-guided optimization of the hit compound CTN1122 in the design of promising imidazo[1; 2-a]pyrazine derivatives targeting the casein kinase 1 for antileishmanial therapy

以药效团为指导对靶向酪蛋白激酶1的抗利什曼原虫治疗中具有潜力的咪唑并[1; 2-a]吡嗪衍生物进行先导化合物CTN1122的优化设计

RSC Med. Chem.
IF3.6
2025-08-140
PRE
Lhana Tisseur; Cédric Logé; Sandrine Cojean; Khadidiatou Gassama; Lilian Karcher; Fabrice Pagniez; Christian Cavé; Guillaume Bernadat; Philippe M. Loiseau; Stéphane Bach; Jérôme Thiéfaine; Justine Bonnet; Carine Picot; Christophe Tomasoni; Olivier Leclercq; Blandine Baratte; Thomas Robert; Patrice Le Pape; Najma Rachidi; Marc-Antoine Bazin; Pascal Marchand
2-Aminothiophene Derivatives-New Drug Candidates Against Leishmaniasis: Drug Design, Synthesis, Pharmacomodulation, and Antileishmanial Activity
PHARMACEUTICALS
IF4.8
2025-01-170
OAAI
de Araujo, Rodrigo Santos Aquino; Bernardo, Vitoria Gaspar; Tiburcio, Robert da Silva; Bedor, Danilo Cesar Galindo; de Campos, Michel Leandro; Pontarolo, Roberto; de Sousa, Julyanne Maria Saraiva; Rodrigues, Klinger Antonio da Franca; Scotti, Marcus Tullius; Nayarisseri, Anuraj; Marchand, Pascal; Mendonca-Junior, Francisco Jaime Bezerra
Investigating the C2 Modulation of the Imidazo[1,2-a]pyrazine-Based Hit Compound CTN1122: Synthesis, in vitro Antileishmanial Activity, Cytotoxicity and Casein Kinase 1 Inhibition

研究基于咪唑并 [1，2-a] 吡嗪的命中化合物CTN1122的C2调节: 合成，体外抗利什曼蛋白活性，细胞毒性和酪蛋白激酶1抑制

CHEMMEDCHEM
IF3.4
2025-01-060
PRE
Tisseur, Lhana; Cojean, Sandrine; Gassama, Khadidiatou; Loge, Cedric; Pagniez, Fabrice; Cave, Christian; Bernadat, Guillaume; Loiseau, Philippe M.; Bach, Stephane; Thiefaine, Jerome; Picot, Carine; Tomasoni, Christophe; Leclercq, Olivier; Baratte, Blandine; Robert, Thomas; Le Pape, Patrice; Rachidi, Najma; Bazin, Marc-Antoine; Marchand, Pascal
29th Annual GP2A Medicinal Chemistry Conference

第29届GP2A药物化学年会

PHARMACEUTICALS
IF4.8
2021-12-070
OAAI
Helesbeux, Jean-Jacques; Carro, Laura; McCarthy, Florence O.; Moreira, Vania M.; Giuntini, Francesca; O'Boyle, Niamh; Matthews, Susan E.; Bayraktar, Guelsah; Bertrand, Samuel; Rochais, Christophe; Marchand, Pascal
In vitro identification of imidazo[1,2-a]pyrazine-based antileishmanial agents and evaluation of L. major casein kinase 1 inhibition
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
2021-01-0117
OAAI
Bazin, Marc-Antoine; Cojean, Sandrine; Pagniez, Fabrice; Bernadat, Guillaume; Cave, Christian; Ourliac-Garnier, Isabelle; Nourrisson, Marie-Renee; Morgado, Cathy; Picot, Carine; Leclercq, Olivier; Baratte, Blandine; Robert, Thomas; Spath, Gerald F.; Rachidi, Najma; Bach, Stephane; Loiseau, Philippe M.; Le Pape, Patrice; Marchand, Pascal
Biological Evaluation of Arylsemicarbazone Derivatives as Potential Anticancer Agents
PHARMACEUTICALS
IF4.8
2019-11-177
OAAI
Nascimento da Cruz, Anne Cecilia; Brondani, Dalci Jose; de Santana, Temistocles I'talo; da Silva, Lucas Oliveira; da Oliveira Borba, Elizabeth Fernanda; de Faria, Antonio Rodolfo; Cavalcanti de Albuquerque, Julianna Ferreira; Piessard, Sylvie; Ximenes, Rafael Matos; Baratte, Blandine; Bach, Stephane; Ruchaud, Sandrine; Bezerra Mendonca Junior, Francisco Jaime; Bazin, Marc-Antoine; Rabello, Marcelo Montenegro; Hernandes, Marcelo Zaldini; Marchand, Pascal; da Silva, Teresinha Goncalves

研究方向

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S
Stéphane Bach
H 指数:30论文数:219被引数:3,201
P
Patrice Le Pape
H 指数:38论文数:224被引数:4,549
B
Blandine Baratte
H 指数:22论文数:114被引数:1,788
M
Marc‐Antoine Bazin
H 指数:14论文数:40被引数:646
T
Thomas Robert
H 指数:32论文数:168被引数:3,476
S
Sandrine Cojean
H 指数:24论文数:102被引数:1,583
F
Florence O. McCarthy
H 指数:22论文数:67被引数:1,481
F
Fabrice Pagniez
H 指数:20论文数:64被引数:1,217
C
Carine Picot
H 指数:13论文数:39被引数:494
M
Marie‐Renée Nourrisson
H 指数:12论文数:37被引数:409