Redhead, Martin A.; Owen, C. David; Brewitz, Lennart; Collette, Amelia H.; Lukacik, Petra; Strain-Damerell, Claire; Robinson, Sean W.; Collins, Patrick M.; Schafer, Philipp; Swindells, Mark; Radoux, Chris J.; Hopkins, Iva Navratilova; Fearon, Daren; Douangamath, Alice; von Delft, Frank; Malla, Tika R.; Vangeel, Laura; Vercruysse, Thomas; Thibaut, Jan; Leyssen, Pieter; Nguyen, Tu-Trinh; Hull, Mitchell; Tumber, Anthony; Hallett, David J.; Schofield, Christopher J.; Stuart, David I.; Hopkins, Andrew L.; Walsh, Martin A.

Bispecific repurposed medicines targeting the viral and immunological arms of COVID-19

SCIENTIFIC REPORTS

IF3.9

2021-06-2428

OAAI

Redhead, Martin A.; Owen, C. David; Brewitz, Lennart; Collette, Amelia H.; Lukacik, Petra; Strain-Damerell, Claire; Robinson, Sean W.; Collins, Patrick M.; Schaefer, Philipp; Swindells, Mark; Radoux, Chris J.; Hopkins, Iva Navratilova; Fearon, Daren; Douangamath, Alice; von Delft, Frank; Malla, Tika R.; Vangeel, Laura; Vercruysse, Thomas; Thibaut, Jan; Leyssen, Pieter; Tu-Trinh Nguyen; Hull, Mitchell; Tumber, Anthony; Hallett, David J.; Schofield, Christopher J.; Stuart, David I.; Hopkins, Andrew L.; Walsh, Martin A.

Faropenem reacts with serine and metallo-β-lactamases to give multiple products

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2021-04-0114

OAAI

Mass spectrometry reveals potential of β-lactams as SARS-CoV-2 Mpro inhibitors

CHEMICAL COMMUNICATIONS

IF4.2

2021-01-0133

OAAI

Discovery of SARS-CoV-2 Mpro peptide inhibitors from modelling substrate and ligand binding

CHEMICAL SCIENCE

IF7.4

2021-01-0155

OAAI

Chan, H. T. Henry; Moesser, Marc A.; Walters, Rebecca K.; Malla, Tika R.; Twidale, Rebecca M.; John, Tobias; Deeks, Helen M.; Johnston-Wood, Tristan; Mikhailov, Victor; Sessions, Richard B.; Dawson, William; Salah, Eidarus; Lukacik, Petra; Strain-Damerell, Claire; Owen, C. David; Nakajima, Takahito; Swiderek, Katarzyna; Lodola, Alessio; Moliner, Vicent; Glowacki, David R.; Spencer, James; Walsh, Martin A.; Schofield, Christopher J.; Genovese, Luigi; Shoemark, Deborah K.; Mulholland, Adrian J.; Duarte, Fernanda; Morris, Garrett M.

Allosteric Inhibition of the SARS-CoV-2 Main Protease: Insights from Mass Spectrometry Based Assays

SARS-CoV-2主要蛋白酶的变构抑制: 基于质谱的分析的见解

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2020-10-1592

OAAI

Non-Hydrolytic β-Lactam Antibiotic Fragmentation by L,D-Transpeptidases and Serine β-Lactamase Cysteine Variants

L，D-转肽酶和丝氨酸 β-内酰胺酶半胱氨酸变体的非水解 β-内酰胺抗生素片段化

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2019-01-2123

OAAI