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B

Bin Sun

MRC Laboratory of Medical Sciences
H指数:18
被引数:1,412

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Spliceosome induction is a druggable dependency of RAS-driven senescence and cancer

剪接体诱导是RAS驱动的衰老和癌症的药物依赖性

Nature Communications
IF15.7
2026-04-150
OAAI
Verena Wagner; Laura Bousset; Mariana Ascensão-Ferreira; Bin Sun; José Efren Barragan Avila; Alexandre Kaizeler; Rita Martins-Silva; Mohammad Rahbari; Mirian Fernández-Vaquero; Scott Haston; Michele Tinti; Joaquim Pombo; Sanjay Khadayate; Susanne Roth; Christian M. Schürch; Juan Pedro Martínez-Barbera; Anat Bahat; Keng Boon Wee; Jennifer P. Morton; Nisar Malek; Andrew J. Innes; Santiago Vernia; Nuno L. Barbosa-Morais; Suchira Gallage; Mathias Heikenwalder; Jesús Gil
COPI vesicle formation and N-myristoylation are targetable vulnerabilities of senescent cells

COPI囊泡形成和N-肉豆蔻酰化是衰老细胞的可靶向脆弱性

NATURE CELL BIOLOGY
IF19.1
2023-11-2712
OAAI
McHugh, Domhnall; Sun, Bin; Gutierrez-Munoz, Carmen; Hernandez-Gonzalez, Fernanda; Mellone, Massimiliano; Guiho, Romain; Duran, Imanol; Pombo, Joaquim; Pietrocola, Federico; Birch, Jodie; Kallemeijn, Wouter W.; Khadayate, Sanjay; Dharmalingam, Gopuraja; Vernia, Santiago; Tate, Edward W.; Martinez-Barbera, Juan Pedro; Withers, Dominic J.; Thomas, Gareth J.; Serrano, Manuel; Gil, Jesus
Cardiac glycosides are broad-spectrum senolytics

强心苷是广谱抗衰老药

NATURE METABOLISM
IF20.8
2019-10-21225
OAAI
Guerrero, Ana; Herranz, Nicolas; Sun, Bin; Wagner, Verena; Gallage, Suchira; Guiho, Romain; Wolter, Katharina; Pombo, Joaquim; Irvine, Elaine E.; Innes, Andrew J.; Birch, Jodie; Glegola, Justyna; Manshaei, Saba; Heide, Danijela; Dharmalingam, Gopuraja; Harbig, Jule; Olona, Antoni; Behmoaras, Jacques; Dauch, Daniel; Uren, Anthony G.; Zender, Lars; Vernia, Santiago; Martinez-Barbera, Juan Pedro; Heikenwalder, Mathias; Withers, Dominic J.; Gil, Jesus

研究方向

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F
Francis G. Szele
H 指数:35论文数:114被引数:3,775
J
Jesús Gil
H 指数:72论文数:232被引数:2.9万
S
Santiago Vernia
H 指数:26论文数:66被引数:2,297
J
Juan Pedro Martı́nez-Barberá
H 指数:59论文数:227被引数:1.2万
S
Suchira Gallage
H 指数:18论文数:49被引数:2,958
I
István Adorján
H 指数:13论文数:61被引数:1,197
K
Keith W. Vance
H 指数:17论文数:64被引数:1,995
J
Joaquim Pombo
H 指数:17论文数:54被引数:1,473
F
Farah Alammari
H 指数:3论文数:9被引数:100
D
Dominic J. Withers
H 指数:60论文数:158被引数:2.0万