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梁

梁宏 (Hong Liang)

ministry of science and technology

41H指数
193论文数
5.0K被引数
收录论文 97
发表时间
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A Colorimetric Aptasensor for Rapid Detection of Sulfadimethoxine in Aquaculture水产品中磺胺间甲氧嘧啶的快速比色适配体传感器检测
errBiosensors-Basel
IF5.6
err2026-08-06
err0
errOAAI
errHong Liang; Jiahao Tan; Tingyu Wang; Yaomei Wang; Chen Zhang
err分享
err收藏
Designing anticancer copper(II) complexes by optimizing 2-pyridine-thiosemicarbazone ligands (vol. 158, pg. 442, 2018)通过优化2-吡啶-硫代氨羧肟配体设计抗癌铜(II)配合物（vol. 158, pg. 442, 2018）
errEuropean Journal of Medicinal Chemistry
IF5.9
err2026-08-01
err0
PREAI
errDeng, Jungang; Yu, Ping; Zhang, Zhenlei; Wang, Jun; Cai, Jinhua; Wu, Na; Sun, Hongbin; Liang, Hong; Yang, Feng
err分享
err收藏
A Flight Path Angle Reconstruction-Based Polynomial Guidance Law with Multiple Constraints基于飞行路径角重构的多约束多项式制导律
errAerospace
IF2.2
err2026-04-20
err0
errOAAI
errLiang, Hong; Zhang, Zechen; Chang, Sijiang
err分享
err收藏
Designing mitophagy-targeted robustine- and 4-acridinol-rhodium(III) coordination compounds to overcome cisplatin resistance in A549/DDP lung cancer cells设计靶向线粒体自噬的罗丹明-robustine和4-乙酰啶醇-钌(III)配合物，以克服A549/DDP肺癌细胞的顺铂耐药性
errNew J. Chem.
IF0
err2025-12-06
err0
PREAI
errTai-ming Shao; Hai-Xia Liao; Qiu-Ming Li; Mingxiong Tan; Chun-Jie Liang; Hong Liang; Qi-Pin Qin
err分享
err收藏
In vitro and in vivo studies on three new 8-hydroxyquinoline-based zinc(II) coordination compounds as potential antimelanoma cancer agents体外和体内研究三种新型8-羟基喹啉基锌(II)配位化合物作为潜在的抗黑素瘤癌症药物。
errBioorganic Chemistry
IF4.7
err2025-10-28
err0
PREAI
errQing Su; Li-Lin Jiang; Qiu-Ming Li; Ju-Mei Zhang; Li-Qin Qin; Ming-Xiong Tan; Hong Liang; Qi-Pin Qin
err分享
err收藏
Dual-action arene‑osmium(II) oxoaporphine complex combats bladder cancer via microtubule disruption and PINK1/Parkin mitophagy induction双功能芳烃-锇(II)氧阿朴啡配合物通过微管破坏和PINK1/Parkin线粒体自噬诱导来对抗膀胱癌
errInorganic Chemistry Communications
IF5.4
err2025-10-06
err0
PREAI
errLan-Shan Liao; Shan-Guang Wu; Jin-Xuan Zheng; Yu-Lan Li; Sukanya Dej-adisai; Gui-Fa Su; Hong Liang; Zhen-Feng Chen
err分享
err收藏
`Integrated multi-modal dissection of IVIg-mediated immune reprogramming in lupus mice整合多模态分析IVIg介导的狼疮小鼠免疫重编程
errLife Sciences
IF5.1
err2025-10-03
err0
PREAI
errXin Yuan; Pan Sun; Tong Wang; Wei Zhang; Peng Jiang; Hong Liang; Xiaochen Yan; Tiancheng Chu; Xi Du; Shengliang Ye; Li Ma; Ping Fu; Zongkui Wang; Changqing Li
err分享
err收藏
Aggressive B cell lymphomas retain ATR-dependent determinants of T cell exclusion from the germinal center dark zone弥漫大B细胞淋巴瘤保留ATR依赖性的生发中心暗区T细胞排斥决定因素
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2025-09-16
err0
errOAAI
errCancila, Valeria; Bertolazzi, Giorgio; Chan, Allison S. Y.; Medico, Giovanni; Bastianello, Giulia; Morello, Gaia; Paysan, Daniel; Lai, Clemence; Hong, Liang; Shenoy, Girija; Jaynes, Patrick W.; Schiavoni, Giovanna; Mattei, Fabrizio; Piconese, Silvia; Revuelta, Maria V.; Noto, Francesco; Businaro, Luca; Ninno, Adele De; Cammarata, Ilenia; Pagni, Fabio; Venkatachalapathy, Saradha; Sangaletti, Sabina; Di Napoli, Arianna; Cicio, Giada; Vacca, Davide; Lonardi, Silvia; Lorenzi, Luisa; Ferreri, Andres J. M.; Belmonte, Beatrice; Liu, Min; Lakshmanan, Manikandan; Ong, Michelle S. N.; Zhang, Biyan; See, Tingyi; Lam, Kong-Peng; Varano, Gabriele; Colombo, Mario P.; Bicciato, Silvio; Inghirami, Giorgio; Cerchietti, Leandro; Ponzoni, Maurilio; Zappasodi, Roberta; Metzger, Evelyn; Beechem, Joseph; Facchetti, Fabio; Foiani, Marco; Casola, Stefano; Jeyasekharan, Anand D.; Tripodo, Claudio
err分享
err收藏
Nanopores-coupled SERS platforms on superslippery surfaces using Au&Ag alloy pillars for biomolecules enrichment and detection基于Au&Ag合金柱的超滑表面纳米孔耦合SERS平台用于生物分子富集与检测
errRare Metals
IF11
err2025-09-10
err0
PREAI
errShuangshuang Zhao; Yongjun Zhang; Jiahong Wen; Liang Hong; Wenshi Zhao; Fan Zhang; Yaxin Wang; Renxian Gao; Kun Zhang; Rufei Cui; Fengyi Zhang; Yang Liu; Shikuan Yang; Xiaoyu Zhao
err分享
err收藏
The lanthanide(III) complexes of new fluoropyrimidine hydrazone 8-quinolinol ligand: Synthesis, crystal structure and bioactive studies
errJOURNAL OF MOLECULAR STRUCTURE
IF4.7
err2025-04-01
err0
PREAI
errJiang, Xiao-hong; Bi, Xue-bin; Ding, Tong-yan; Zahoor, Sana; Liu, Rui-xue; Liu, Yan-cheng; Liang, Hong
err分享
err收藏
Copper(II) Complexes of Pyrazolopyrimidine Derivatives as Anticancer Agents with Enhanced Chemodynamic Therapy through Bimodal Apoptosis and Ferroptosis吡唑嘧啶衍生物的铜(II)配合物作为通过双向凋亡和铁死亡增强化学动力学疗法的抗癌剂
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2025-03-26
err0
PREAI
errYang, Kun; Chen, Qian; Chen, Juan; Geng, Lu-Fei; Ma, Meng-Xue; Gu, Yun-Qiong; Choudhary, Muhammad Iqbal; Liang, Hong
err分享
err收藏
A DNA concatemer-encoded CRISPR/Cas12a fluorescence sensor for sensitive detection of Pb2+ based on DNAzymes
errANALYST
IF3.3
err2025-03-01
err0
PREAI
errHe, Shaoying; Lin, Wei; Liu, Xin; Li, Fei; Liang, Hong; Xu, Huo; Lu, Chunhua; Xing, Chao
err分享
err收藏
A Smart mRNA-Initiated Theranostic Multi-shRNA Nanofactory for Precise and Efficient Cancer Gene Therapy一种智能mRNA启动的theranostic多shRNA纳米工厂，用于精确高效的癌症基因治疗
errADVANCED HEALTHCARE MATERIALS
IF9.6
err2025-01-10
err0
PREAI
errShi, M; He, YF; Zhong, XH; Huang, HK; Hua, J; Wang, SL; Xu, JY; Zhao, SL; Liang, H; Huang, Y
err分享
err收藏
Design of a theranostic Gd (III)-Cu (I) complex to inhibit growth and metastasis of triple-negative breast cancer一种用于抑制三阴性乳腺癌生长和转移的诊疗用Gd(III)-Cu(I)配合物的设计
errRARE METALS
IF11
err2025-01-09
err0
PREAI
errMan, Xue-Yu; Zhu, Ming-Hui; Li, Shan-He; Li, Wen-Juan; Xu, Gang; Zhang, Zhen-Lei; Wu, Xiao-Yang; Liang, Hong
err分享
err收藏
Developing an Arene Binuclear Ruthenium(II) Complex to Induce Ferroptosis and Activate the cGAS-STING Pathway: Targeted Inhibiting Growth and Metastasis of Triple Negative Breast Cancer
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-10-22
err0
PREAI
errXu, Gang; Liang, Qiongyue; Gao, Lijuan; Xu, Shihang; Luo, Weicong; Wu, Qiuming; Li, Jingyuan; Zhang, Zhenlei; Liang, Hong; Yang, Feng
err分享
err收藏
Insights into the antineoplastic activity and mechanisms of action of coumarin-coordinated 8-hydroxyquinoline ruthenium(II/III) compounds
errJOURNAL OF INORGANIC BIOCHEMISTRY
IF3.2
err2024-10-01
err1
PREAI
errDu, Ling-Qi; Yang, Yan; Ruan, Li; Sun, Song; Mo, Dong-Yin; Cai, Jin-Yuan; Liang, Hong; Shu, Sai; Qin, Qi-Pin
err分享
err收藏
Developing a Rhodium(III) Complex to Reprogram the Tumor Immune and Metabolic Microenvironments: Overcoming Multidrug Resistance and Metastasis in Non-Small Cell Lung Cancer
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-09-19
err1
PREAI
errLi, Wenjuan; Li, Shanhe; Zhu, Minghui; Xu, Gang; Man, Xueyu; Zhang, Zhenlei; Liang, Hong; Yang, Feng
err分享
err收藏
Developing a Palladium(II) Agent to Overcome Multidrug Resistance and Metastasis of Liver Tumor by Targeted Multiacting on Tumor Cell, Inactivating Cancer-Associated Fibroblast and Activating Immune Response
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-09-05
err2
PREAI
errJiang, Ming; Li, Wenjuan; Liang, Jinzhe; Pang, Min; Li, Shanhe; Xu, Gang; Zhu, Minghui; Liang, Hong; Zhang, Zhenlei; Yang, Feng
err分享
err收藏
Rational Design of a Hetero-multinuclear Gadolinium(III)-Copper(II) Complex: Integrating Magnetic Resonance Imaging, Photoacoustic Imaging, Mild Photothermal Therapy, Chemotherapy and Immunotherapy of Cancer
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-08-15
err1
PREAI
errMan, Xueyu; Li, Wenjuan; Zhu, Minghui; Li, Shanhe; Xu, Gang; Zhang, Zhenlei; Liang, Hong; Yang, Feng
err分享
err收藏
Rhodium(III) Complex Noncanonically Potentiates Antitumor Immune Responses by Inhibiting Wnt/β-Catenin Signaling
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-08-12
err2
PREAI
errWang, Feng-Yang; Yang, Liang-Mei; Xiong, Xiao-Lin; Yang, Jing; Yang, Yan; Tang, Jiu-Qin; Gao, Lei; Lu, Yuan; Wang, Yuan; Zou, Taotao; Liang, Hong; Huang, Ke-Bin
err分享
err收藏

研究方向

中药活性成分金属药物化学生物学内源性蛋白质金属药物载运体系诊疗一体化纳米医药材料生命过程实时原位监测新方法主要学术兼职英国皇家化学会会士（FRSC）（2015年）中国化学会会士（FCCS）（2024年）中国化学会理事（1998年起）生物无机化学Disulfidptosis-apoptosisHepatocellular carcinomaMetabolic sabotageRedox catalysis, 45145-45156.oxoaporphine-metformin铑(III)混合配合物抗糖尿病抗癌天然产物全合成去对称化策略金属有机框架药物递送控释单分子治疗诊断金属配合物生物成像癌症治疗基于异喹啉生物碱的环金属化铱(III)配合物通过自噬依赖性铁死亡诱导免疫原性细胞死亡和IDO抑制铜(II)配合物协同增强细胞毒性及抗肿瘤免疫反应细胞氧化还原稳态靶向抗肿瘤配合物点击反应靶向联合治疗近红外-II激活光声成像声动力增强光热/光动力治疗纳米诊疗剂近红外二区光声成像光热治疗免疫检查点阻断钌(II)/锇(II)配合物抗癌活性葡萄糖代谢重编程铱(III)基免疫原性细胞死亡诱导剂未折叠蛋白反应调节因子BiP炎症性肠病肠道屏障多靶点抗癌金属配合物人血清白蛋白相互作用铂基化合物Mcl-1抑制剂抗肿瘤治疗anticancer Platinum(II) compoundhuman serum albuminLatexin缺陷在脂肪细胞分化及肥胖代谢紊乱中的作用非铂金属基抗癌治疗剂递送系统抗癌药物设计金(III)抗胶质瘤药物设计铁蛋白纳米颗粒自噬与凋亡诱导金属配合物细胞凋亡Mcl-1 inhibitorAntitumor agentMedicinal Chemistry脑肿瘤抑制铜(II)化合物G-四链体DNA端粒酶抑制有机铂(II)配合物G-四链体DNA稳定肿瘤细胞凋亡近10年以来承担的主要科研项目广西道地药材活性成分金属配位优化及其肿瘤化学免疫治疗化学生物学研究基于中药活性成分金属抗肿瘤配合物研究中药活性成分金属抗肿瘤配合物天然环肽类潜药化学组装与活性评价氧化(异)阿朴菲生物碱金属化合物细胞毒活性免疫激活响应抗肿瘤药物金属基药物血清白蛋白相互作用天然活性物质发现结构改造功能研究中药活性成分无机药物载运体系小龙虾细菌性疾病防治中草药主要荣誉称号国家“万人计划”（百千万工程）领军人才（2016年）广西院士后备人选培养工程首批人选（2016年）中国科协“西部开发突出贡献奖”（2008年）全国优秀科技工作者（2005年）教育部第三届“高校青年教师奖”（2002年）中国青年科技奖（2001年）国家有突出贡献的中青年专家（1999年）广西优秀专业技术人员（1999年）“广西十百千人才工程”第一层次人选（1998年）国家“百千万人才工程”首批人选（1996年）国务院政府特殊津贴（1996年）广西优秀专家（1996年）
合作学者
合作期刊
谭蔚泓 封面图
谭蔚泓 (Weihong Tan)
H 指数: 168 · 论文数: 1.4K
张勇 封面图
张勇 (Yong Zhang)
H 指数: 125 · 论文数: 2.2K
王军 封面图
王军 (Jun Wang)
H 指数: 122 · 论文数: 1.6K
刘
刘刚 (Gang Liu)
H 指数: 110 · 论文数: 1.4K
杨黄浩 封面图
杨黄浩 (Huanghao Yang)
H 指数: 110 · 论文数: 549
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