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D

Daniel Weekes

The Institute of Cancer Research
H指数:13
被引数:1,397

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Tumour specific HORMAD1 expression perturbs mitotic arrest and drives sensitivity to mitotic kinase inhibitors

肿瘤特异性HORMAD1表达扰乱有丝分裂停滞并驱动对有丝分裂激酶抑制剂的敏感性

Nature Communications
IF15.7
2026-03-110
OAAI
Callum Walker; Gabriel Kollarovic; Daniel Weekes; Jennifer Trendell; Ricarda M. Hoffmann; Alexia Martin; Riccardo Ferro; Blanca Navarro-Llinas; Luke Hitchen; Mercedes Pardo Calvo; Nicolae Balan; Harriet Kemp; Alexandra Carroll; Kathryn Davidson; Sarmi Nath; Nadja D’Uonno; Ruifang Lu; Chris Starling; Marieke Otten; Nino Iakobachvili; Chiara Marcozzi; Ilhan Rahman; Jelmar Quist; Lu Yu; Dragomir B. Krastev; Valeria Amodeo; Ioannis Roxanis; Anita Grigoriadis; Richard Bayliss; Jyoti Choudhary; Syed Haider; Jonathon Pines; Stephen J. Pettitt; Christopher J. Lord; Andrew N. J. Tutt
Functional assessment of RAD51 foci and replication fork dynamics in PARPi resistant BRCA1/2 mutated breast cancer
CANCER RESEARCH
IF16.6
2024-05-020
PRE
Harvey-Jones, Elizabeth; Raghunandan, Maya; Robbez-Masson, Luisa; Alaguthurai, Thanussuyah; Llop-Guevara, Alba; Trendell, Jennifer; Rodriguez, Olga; Guzman, Marta; Weekes, Daniel; deRenty, Christelle; Knight, Eleanor; Marlow, Rebecca; Starling, Christopher; Liu, Ruifang; Ravindran, Nivedita; Roxanis, Ioannis; Lukashchuk, Natalia; Serra, Violeta; Pettitt, Stephen; Lord, Christopher; Tutt, Andrew N. J.
The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin

泛素依赖性ATPase p97从染色质中去除细胞毒性捕获的PARP1

NATURE CELL BIOLOGY
IF19.1
2022-01-1087
OAAI
Krastev, Dragomir B.; Li, Shudong; Sun, Yilun; Wicks, Andrew; Hoslett, Gwendoline; Weekes, Daniel; Badder, Luned M.; Knight, Eleanor G.; Marlow, Rebecca; Calvo, Mercedes Pardo; Yu, Lu; Talele, Tanaji T.; Bartek, Jiri; Choudhary, Jyoti; Pommier, Yves; Pettitt, Stephen J.; Tutt, Andrew; Ramadan, Kristijan; Lord, Christopher J.
The anion channel GPHR/GPR89 regulates protein-folding homeostasis by regulating the IRE1α pathway in breast cancer
CANCER RESEARCH
IF16.6
2018-07-010
PRE
Ferro, Riccardo; Marra, Pierfrancesco; Pereira, Ana Mendes; Reen, Virinder; Prince, Cynthia; Mathew, Sumi; Facchetti, Alessandra; Ghongane-Salpe, Priyanka; Kareemaghay, Sedigeh; Gazinska, Patrycja; Robertson, David; Noor, Farzana; Maristany, Fara Braso'; Weekes, Daniel; Krastev, Dragomir; Tenev, Tencho; Mirza, Hasan; Patel, Nirmesh; Grigoriadis, Anita; Tutt, Andrew
Integrated genomics and functional validation identifies malignant cell specific dependencies in triple negative breast cancer
NATURE COMMUNICATIONS
IF15.7
2018-03-1346
OAAI
Patel, Nirmesh; Weekes, Daniel; Drosopoulos, Konstantinos; Gazinska, Patrycja; Noel, Elodie; Rashid, Mamun; Mirza, Hasan; Quist, Jelmar; Braso-Maristany, Fara; Mathew, Sumi; Ferro, Riccardo; Pereira, Ana Mendes; Prince, Cynthia; Noor, Farzana; Francesch-Domenech, Erika; Marlow, Rebecca; de Rinaldis, Emanuele; Grigoriadis, Anita; Linardopoulos, Spiros; Marra, Pierfrancesco; Tutt, Andrew N. J.
An integrated copy number and gene expression genomics analysis and RNAi approach identifies and validates the KIFC1 kinesin as a malignant cell selective target in triple negative breast cancer
CANCER RESEARCH
IF16.6
2016-07-150
PRE
Patel, Nirmesh S.; Drosopoulos, Konstantinos; Weekes, Daniel; Noel, Elodie; Mirza, Hasan; Rashid, Mamunur; de Rinaldis, Emanuele; Maristany, Fara Braso; Mathew, Sumi; Domenech, Erika Francesch; Gazinska, Patrycja; Noor, Farzana; Quist, Jelmar; Marlow, Rebecca; Grigoriadis, Anita; Linardopoulos, Spiros; Tutt, Andrew N.
Genomic Complexity Profiling Reveals That HORMAD1 Overexpression Contributes to Homologous Recombination Deficiency in Triple-Negative Breast Cancers
CANCER DISCOVERY
IF33.3
2015-05-03106
OAAI
Watkins, Johnathan; Weekes, Daniel; Shah, Vandna; Gazinska, Patrycja; Joshi, Shalaka; Sidhu, Bhavna; Gillett, Cheryl; Pinder, Sarah; Vanoli, Fabio; Jasin, Maria; Mayrhofer, Markus; Isaksson, Anders; Cheang, Maggie C. U.; Mirza, Hasan; Frankum, Jessica; Lord, Christopher J.; Ashworth, Alan; Vinayak, Shaveta; Ford, James M.; Telli, Melinda L.; Grigoriadis, Anita; Tutt, Andrew N. J.

研究方向

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A
Andrew Tutt
H 指数:103论文数:781被引数:8.7万
A
Anita Grigoriadis
H 指数:52论文数:533被引数:1.1万
C
Christopher J. Lord
H 指数:98论文数:708被引数:4.5万
S
Stephen J. Pettitt
H 指数:31论文数:214被引数:5,616
P
Patrycja Gazińska
H 指数:30论文数:253被引数:4,501
R
Rebecca Marlow
H 指数:22论文数:114被引数:2,726
D
Dragomir B. Krastev
H 指数:18论文数:109被引数:3,015
H
Hasan Mirza
H 指数:13论文数:181被引数:802
R
Riccardo Ferro
H 指数:12论文数:19被引数:531
E
Elodie Noël
H 指数:8论文数:32被引数:545