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J

Jian Lei

Sichuan University
H指数:20
被引数:2,858

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First-line anlotinib versus bevacizumab plus CapeOX in RAS/BRAF wild-type unresectable metastatic colorectal cancer (ANCHOR): a multicenter, prospective, randomized, phase 3 trial

ANCHOR研究：一线安罗替尼与贝伐珠单抗联合卡培他滨/奥沙利铂治疗RAS/BRAF野生型不可切除转移性结直肠癌的多中心、前瞻性、随机、III期临床试验

Signal Transduction and Targeted Therapy
IF52.7
2026-09-010
OA
Yue Liu; Yanqiao Zhang; Rongbo Lin; Xiaobing Chen; Junye Wang; Mudan Yang; Xiujuan Qu; Yunfeng Li; Jiayi Li; Weisheng Zhang; Yong Mao; Ziwei Wang; Zhenyang Liu; Jian Lei; Ye Xu; Yi Jiang; Zhanyu Pan; Liangjun Zhu; Chengcheng Liu; Min Song; Ying Yuan; Kefeng Ding
YL1004 is a SARS-CoV-2 papain-like protease inhibitor with immunomodulatory and antiviral activity in mice

YL1004是一种SARS-CoV-2的木瓜蛋白酶样蛋白酶抑制剂，在小鼠中具有免疫调节和抗病毒活性

Nature Communications
IF15.7
2026-01-260
OA
Jinshan Nan; Huiping Shuai; Jingxin Qiao; Rui Zeng; Lianzhao Du; Yan Chen; Chaemin Yoon; Jiaheng Hu; Wenyu Guo; Lei Wang; Chong Huang; Lengjing Zhu; Yueshan Li; Shanshan Zhang; Xinyue Deng; Jingxuan Sun; Le Du; Ronggang Ma; Qiao Huang; Jian Lei; Hin Chu; Shengyong Yang
Discovery of Highly Potent and Selective SOS1 Inhibitors for the Treatment of KRAS-Driven Colorectal Cancer

发现用于治疗KRAS驱动的结直肠癌的高效且选择性SOS1抑制剂

Journal of Medicinal Chemistry
IF6.8
2026-01-010
PRE
Xingchen Liu; Yuzhou Xiao; Yanmei Zhou; Yaxin Teng; Jing Zou; Yue Zhou; Xinyu Fan; J Zhao; Jiahao Qiu; Lingfeng Tang; Z Qiu; Jing Xu; Haoyue Luo; Xiaodan Pan; Wenjing Xu; Bo Ren; Kun Gou; Chunqi Liu; Yukun Ren; Jialing Song; Ping Gao; Xia Zhou; Laiying Zhang; Xinying Qian; Jian Lei; Xiaobo Cen; Youfu Luo; Yinglan Zhao
Author Correction: An orally available Mpro/TMPRSS2 bispecific inhibitor with potent anti-coronavirus efficacy in vivo

作者更正：一种口服可用的Mpro/TMPRSS2双特异性抑制剂，具有体内强效抗冠状病毒疗效

Nature Communications
IF15.7
2025-12-150
OAAI
Huiping Shuai; Jingxin Qiao; Chaemin Yoon; Guo Zhang; Yuxin Hou; Xiaoyan Xia; Lei Wang; Xinyue Deng; Yifei Wang; Qingquan Li; Lianzhao Du; Yuanchen Liu; Minmin Zhou; Hoi Ting Wong; Jiaheng Hu; Huan Liu; Bingjie Hu; Dong Wang; Jingyi Su; Yuying Pan; Yongtao Ye; Yan Chen; Zhen Fang; Ziyi Xia; Yue Chai; Jialu Shi; Yang Wang; Tianrenzheng Zhu; Honglei Zhang; Shuofeng Yuan; Jie Zhou; Jasper Fuk-Woo Chan; Kwok-Yung Yuen; Chunfu Xu; Jian Lei; Shengyong Yang; Hin Chu
The analysis of prognostic value of liver metastatic burden for non-functional pancreatic neuroendocrine tumors with synchronous liver metastasis after curative surgery: a retrospective study in a single center

肝脏转移负荷对同步肝转移的非功能性胰腺神经内分泌肿瘤术后预后的价值分析：一项单中心回顾性研究

JOURNAL OF PANCREATOLOGY
IF1.1
2025-12-010
PRE
Yuan, Meng; Sadula, Abuduhaibaier; Chen, Qing; Meng, Meng; Lei, Ji-an; Ren, Siqian; Chen, Hanwei; Bing, Yuntao; Li, Lei; Lu, Ming; Li, Jie; Yu, Jiangyuan; Yuan, Chunhui
Intranasal vaccine combining adenovirus and trimeric subunit protein provides superior immunity against SARS-CoV-2 Omicron variant

鼻内疫苗结合腺病毒和三聚体亚单位蛋白为SARS-CoV-2 Omicron变种提供更优免疫力

Nature Biomedical Engineering
IF26.6
2025-09-220
OAAI
Weiqi Hong; Ping Cheng; Jingyun Yang; Huashan Shi; Zhenling Wang; Jiong Li; Hong Lei; Dandan Peng; Cai He; Wenyan Ren; Xiangyu Pan; Yuhe Huang; Aqu Alu; Furong Qin; Binhan Wang; Yanan Zhou; Yun Yang; Wenhai Yu; Cong Tang; Qing Huang; Mengli Yang; Bai Li; Jingmei Li; Junbin Wang; Jiayuan Ai; Li Chen; Haiying Que; Zhen Zeng; Jian Liu; Ying Hao; Danyi Ao; Yu Zhang; Xiya Huang; Chunjun Ye; MinYang Fu; Xuemei He; Zhenfei Bi; Xuejiao Han; Min Luo; Hongbo Hu; Wei Cheng; Haohao Dong; Jian Lei; Lu Chen; Xikun Zhou; Wei Wang; Guobo Shen; Jinliang Yang; Xiangrong Song; Yuquan Wei; Shuaiyao Lu; Qiangming Sun; Guangwen Lu; Youchun Wang; Li Yang; Weimin Li; Xiawei Wei
An orally available Mpro/TMPRSS2 bispecific inhibitor with potent anti-coronavirus efficacy in vivo

一种口服可用的Mpro/TMPRSS2双特异性抑制剂，具有体内强效抗冠状病毒活性

Nature Communications
IF15.7
2025-07-160
OA
Huiping Shuai; Jingxin Qiao; Chaemin Yoon; Guo Zhang; Yuxin Hou; Xiaoyan Xia; Lei Wang; Xinyue Deng; Yifei Wang; Qingquan Li; Lianzhao Du; Yuanchen Liu; Minmin Zhou; Hoi Ting Wong; Jiaheng Hu; Huan Liu; Bingjie Hu; Dong Wang; Jingyi Su; Yuying Pan; Yongtao Ye; Yan Chen; Zhen Fang; Ziyi Xia; Yue Chai; Jialu Shi; Yang Wang; Tianrenzheng Zhu; Honglei Zhang; Shuofeng Yuan; Jie Zhou; Jasper Fuk-Woo Chan; Kwok-Yung Yuen; Chunfu Xu; Jian Lei; Shengyong Yang; Hin Chu
A recombinant protein vaccine induces protective immunity against SARS-CoV-2 JN.1 and XBB-lineage subvariants

重组蛋白疫苗可诱导针对SARS-CoV-2 JN.1和XBB谱系亚变体的保护性免疫

SIGNAL TRANSDUCTION AND TARGETED THERAPY
IF52.7
2025-02-260
OA
Yang, Jingyun; Hong, Weiqi; Shi, Huashan; Wang, Zhenling; He, Cai; Lei, Hong; Yan, Hong; Alu, Aqu; Ao, Danyi; Chen, Zimin; Zhou, Yanan; Yang, Hao; Yang, Yun; Yu, Wenhai; Tang, Cong; Wang, Junbin; Li, Bai; Huang, Qing; Hu, Hongbo; Cheng, Wei; Dong, Haohao; Lei, Jian; Chen, Lu; Zhou, Xikun; Yang, Li; Wang, Wei; Shen, Guobo; Yang, Jinliang; Song, Xiangrong; Sun, Qiangming; Wang, Youchun; Li, Jiong; Lu, Guangwen; Wei, Yuquan
Intranasal delivery of a subunit protein vaccine provides protective immunity against JN.1 and XBB-lineage variants

鼻内递送亚单位蛋白疫苗可提供针对JN.1和XBB谱系变体的保护性免疫

Signal Transduction and Targeted Therapy
IF52.7
2024-11-200
OAAI
Hong Lei; Weiqi Hong; Jingyun Yang; Cai He; Yanan Zhou; Yu Zhang; Aqu Alu; Jie Shi; Jian Liu; Furong qin; Danyi Ao; Xiya Huang; Zimin Chen; Hao Yang; Yun Yang; Wenhai Yu; Cong Tang; Junbin Wang; Bai Li; Qing Huang; Hongbo Hu; Wei Cheng; Haohao Dong; Jian Lei; Lu Chen; Xikun Zhou; Jiong Li; Li Yang; Zhenling Wang; Wei Wang; Guobo Shen; Jinliang Yang; Zhiwei Zhao; Xiangrong Song; Guangwen Lu; Qiangming Sun; Youchun Wang; Shuaiyao Lu; Xiawei Wei
An orally available Mpro inhibitor is effective against wild-type SARS-CoV-2 and variants including Omicron
Nature Microbiology
IF19.4
2022-04-270
PRE
Bao-Xue Quan; Huiping Shuai; An-Jie Xia; Yuxin Hou; Rui Zeng; Xin-Lei Liu; Gui-Feng Lin; Jing-Xin Qiao; Wen-Pei Li; Fa-Lu Wang; Kai Wang; Ren-Jie Zhou; Terrence Tsz-Tai Yuen; Ming-Xin Chen; Chaemin Yoon; Ming Wu; Shi-Yu Zhang; Chong Huang; Yi-Fei Wang; Wei Yang; Chenyu Tian; Wei-Min Li; Yu-Quan Wei; Kwok-Yung Yuen; Jasper Fuk-Woo Chan; Jian Lei; Hin Chu; Shengyong Yang

研究方向

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R
Rolf Hilgenfeld
H 指数:61论文数:341被引数:1.8万
杨
杨胜勇
H 指数:57论文数:340被引数:1.4万
A
Albrecht von Brunn
H 指数:34论文数:77被引数:4,564
H
Hin Chu
H 指数:61论文数:236被引数:3.1万
Y
Yifei Wang
H 指数:29论文数:154被引数:4,722
Y
Yue Ma‐Lauer
H 指数:8论文数:12被引数:586
X
Xincheng Ni
H 指数:3论文数:9被引数:486
J
Jingxin Qiao
H 指数:11论文数:38被引数:1,210
R
Rui Zeng
H 指数:9论文数:30被引数:872
G
Guobo Shen
H 指数:36论文数:134被引数:6,108