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杨

杨胜勇 (Shengyong Yang)

sichuan university

57H指数
337论文数
1.5W被引数
收录论文 171
发表时间
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Identification of a Potent and Selective Small-Molecule Inhibitor Targeting the nNOS-PDZ Domain that Exhibits Rapid In Vivo Antidepressant Efficacy鉴定一种靶向nNOS-PDZ结构域的高效且选择性小分子抑制剂，该抑制剂显示出快速的体内抗抑郁功效
errJournal of Medicinal Chemistry
IF6.8
err2026-06-03
err0
PREAI
errLiting Zhang; Zijie Xiong; Shasha Chen; Qiucheng Zhu; Yifei Wang; Qi Lu; Xiaohan Bu; Anjie Xia; Lijuan Chen; Chong Chen; Zhenhua Shao; Linli Li; Shengyong Yang
err分享
err收藏
ARID1A loss drives gastric signet ring cell carcinoma by regulating mucin production and secretionARID1A缺失通过调控粘蛋白的产生和分泌驱动胃印戒细胞癌
errNature Communications
IF15.7
err2026-06-02
err0
errOAAI
errHongyu Liu; Ailing Zhong; Zhenghao Lu; Limin Gao; Mengsha Zhang; Jiaxin Li; Yingjie Wang; Yiyun Wang; Lanxin Zhang; Jiabo Zhang; Xiangyu Pan; Xuelan Chen; Jingyao Chen; Siyu He; Xinyuan Wang; Xudong Wan; Xintong Deng; Tingfa Peng; Jian Wang; Jiajia Du; Kun Yang; Kai Liu; Xinzu Chen; Xiaolong Chen; Zhe Feng; Baohong Wu; Jing Xu; Linyong Zhao; Weihan Zhang; Shengyong Yang; Yuan Wang; Lu Chen; Zhihong Xue; Chengjian Zhao; Lunzhi Dai; Feifei Na; Jiankun Hu; Yu Liu; Chong Chen
err分享
err收藏
Fragment-Aware Contrastive Learning Framework for Molecular Property Prediction分子性质预测的分段感知对比学习框架
errJournal of Chemical Information and Modeling
IF5.3
err2026-04-22
err0
PREAI
errJinxiao Ru; Mengzhe Dai; Xin Yang; Jun Zou; Shengyong Yang
err分享
err收藏
Small-molecule inhibition of the deadenylase CNOT6L as a strategy of obesity treatment小分子抑制去腺苷化酶CNOT6L作为肥胖治疗策略
errActa Pharmaceutica Sinica B
IF14.6
err2026-04-19
err0
errOAAI
errHailin Zhang; Jinlong Zhao; Yueyue Li; Meng Yuan; Wenjing Lei; Shengyong Yang
err分享
err收藏
Publisher Correction: Psychedelics elicit their effects by 5-HT2A receptor-mediated Gi signalling出版商更正: 迷幻药通过5-HT2A受体介导的Gi信号传导引起其作用
errNature
IF48.5
err2026-02-17
err0
PREAI
errZheng Xu; Hongshuang Wang; Jingjing Yu; Yue Deng; Xiaowen Tian; Rongjun Ni; Fan Xia; Lingyi Yang; Chanjuan Xu; Liting Zhang; Renxuan Luo; Peipei Chen; Xiaoyu Zhang; Yuxuan Liu; Jingyu Hou; Miyuan Zhang; Shasha Chen; Lantian Su; Hui Sun; Yixiao He; Dandan Chen; Xiaoting Chen; Zhuang Miao; Jie Xie; Xinlei Liu; Jie Zhao; Bowen Ke; Xiaohe Tian; Linan Zeng; Lingli Zhang; Xiangdong Tang; Shengyong Yang; Jianfeng Liu; Xiaohui Wang; Wei Yan; Zhenhua Shao
err分享
err收藏
Small-molecule inhibition of YTHDC1 as a strategy against acute myeloid leukemia in mouse modelsYTHDC1的小分子抑制作为小鼠模型中急性髓系白血病的策略
errScience Translational Medicine
IF14.6
err2026-02-04
err0
PREAI
errHailin Zhang; Yueshan Li; Yin Zhao; Falu Wang; Guifeng Lin; Ting Niu; He Li; Yueyue Li; Lina Liu; Yue Liang; Yu Shen; Yuyao Yi; Hui Zhou; Shang Lou; Yishan Ye; Yanmin He; Ruicheng Yang; Rui Yao; Chenyu Tian; Pei Zhou; Mengdan Wu; Mingxin Chen; Haixing Xu; Jing You; Yi Liao; Chenlu Yang; Ailin Zhao; Chong Chen; Linli Li; Shanshan Pei; Shengyong Yang
err分享
err收藏
Discovery and Structure–Activity Relationship Studies of Diazepine Derivatives as a New Class of Ferroptosis Inhibitors with Potent Efficacy in the Doxorubicin-Induced Cardiomyopathy Model
errJournal of Medicinal Chemistry
IF6.8
err2026-01-30
err0
PREAI
errJing You; Lu Yang; Yaru Qin; Chenyu Tian; Xin Yang; Mingli Xiang; Linli Li; Shengyong Yang
err分享
err收藏
Psychedelics elicit their effects by 5-HT2A receptor-mediated Gi signalling迷幻药通过5-HT2A受体介导的Gi信号传导引起其作用
errNature
IF48.5
err2026-01-28
err0
PREAI
errZheng Xu; Hongshuang Wang; Jingjing Yu; Yue Deng; Xiaowen Tian; Rongjun Ni; Fan Xia; Lingyi Yang; Chanjuan Xu; Liting Zhang; Renxuan Luo; Peipei Chen; Xiaoyu Zhang; Yuxuan Liu; Jingyu Hou; Miyuan Zhang; Shasha Chen; Lantian Su; Hui Sun; Yixiao He; Dandan Chen; Xiaoting Chen; Zhuang Miao; Jie Xie; Xinlei Liu; Jie Zhao; Bowen Ke; Xiaohe Tian; Linan Zeng; Lingli Zhang; Xiangdong Tang; Shengyong Yang; Jianfeng Liu; Xiaohui Wang; Wei Yan; Zhenhua Shao
err分享
err收藏
YL1004 is a SARS-CoV-2 papain-like protease inhibitor with immunomodulatory and antiviral activity in miceYL1004是一种SARS-CoV-2的木瓜蛋白酶样蛋白酶抑制剂，在小鼠中具有免疫调节和抗病毒活性
errNature Communications
IF15.7
err2026-01-26
err0
errOAAI
errJinshan Nan; Huiping Shuai; Jingxin Qiao; Rui Zeng; Lianzhao Du; Yan Chen; Chaemin Yoon; Jiaheng Hu; Wenyu Guo; Lei Wang; Chong Huang; Lengjing Zhu; Yueshan Li; Shanshan Zhang; Xinyue Deng; Jingxuan Sun; Le Du; Ronggang Ma; Qiao Huang; Jian Lei; Hin Chu; Shengyong Yang
err分享
err收藏
Author Correction: An orally available Mpro/TMPRSS2 bispecific inhibitor with potent anti-coronavirus efficacy in vivo作者更正：一种口服可用的Mpro/TMPRSS2双特异性抑制剂，具有体内强效抗冠状病毒疗效
errNature Communications
IF15.7
err2025-12-15
err0
errOAAI
errHuiping Shuai; Jingxin Qiao; Chaemin Yoon; Guo Zhang; Yuxin Hou; Xiaoyan Xia; Lei Wang; Xinyue Deng; Yifei Wang; Qingquan Li; Lianzhao Du; Yuanchen Liu; Minmin Zhou; Hoi Ting Wong; Jiaheng Hu; Huan Liu; Bingjie Hu; Dong Wang; Jingyi Su; Yuying Pan; Yongtao Ye; Yan Chen; Zhen Fang; Ziyi Xia; Yue Chai; Jialu Shi; Yang Wang; Tianrenzheng Zhu; Honglei Zhang; Shuofeng Yuan; Jie Zhou; Jasper Fuk-Woo Chan; Kwok-Yung Yuen; Chunfu Xu; Jian Lei; Shengyong Yang; Hin Chu
err分享
err收藏
An orally available Mpro/TMPRSS2 bispecific inhibitor with potent anti-coronavirus efficacy in vivo一种口服可用的Mpro/TMPRSS2双特异性抑制剂，具有体内强效抗冠状病毒活性
errNature Communications
IF15.7
err2025-07-16
err0
errOAAI
errHuiping Shuai; Jingxin Qiao; Chaemin Yoon; Guo Zhang; Yuxin Hou; Xiaoyan Xia; Lei Wang; Xinyue Deng; Yifei Wang; Qingquan Li; Lianzhao Du; Yuanchen Liu; Minmin Zhou; Hoi Ting Wong; Jiaheng Hu; Huan Liu; Bingjie Hu; Dong Wang; Jingyi Su; Yuying Pan; Yongtao Ye; Yan Chen; Zhen Fang; Ziyi Xia; Yue Chai; Jialu Shi; Yang Wang; Tianrenzheng Zhu; Honglei Zhang; Shuofeng Yuan; Jie Zhou; Jasper Fuk-Woo Chan; Kwok-Yung Yuen; Chunfu Xu; Jian Lei; Shengyong Yang; Hin Chu
err分享
err收藏
Discovery of 4-((quinolin-8-ylthio)methyl)benzamide derivatives as a new class of SARS-CoV-2 nsp13 inhibitors4-((喹啉-8-基硫)甲基)苯甲酰胺衍生物作为一类新的SARS-CoV-2 nsp13抑制剂的开发
errBIOORGANIC & MEDICINAL CHEMISTRY LETTERS
IF2.2
err2025-07-01
err0
PREAI
errFan, Danchen; Huang, Yuanting; Yao, Rui; Zhang, Guo; Yang, Shengyong; Li, Linli
err分享
err收藏
TIFA suppresses hepatocellular carcinoma progression via MALT1-dependent and -independent signaling pathways (vol 1, 16013, 2016)TIFA通过MALT1依赖性和非依赖性信号通路抑制肝细胞癌进展（vol 1, 16013, 2016）
errSIGNAL TRANSDUCTION AND TARGETED THERAPY
IF52.7
err2025-03-04
err0
errOAAI
errShen, Wenzhi; Du, Renle; Li, Jun; Luo, Xiaohe; Zhao, Shuangtao; Chang, Antao; Zhou, Wei; Gao, Ruifang; Luo, Dehong; Wang, Juan; Hao, Na; Liu, Yanhua; Chen, Yanan; Luo, Yunping; Sun, Peiqing; Yang, Shengyong; Luo, Na; Xiang, Rong
err分享
err收藏
Discovery of phenazine derivatives as a new class of non-classical ferroptosis inhibitors and efficacy evaluation on a mouse model of liver injury
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2025-01-01
err0
PREAI
errWu, Yunjie; Yang, Lu; You, Jing; Tian, Chenyu; Yang, Shengyong; Li, Linli
err分享
err收藏
Discovery and structure-activity relationship study of nicotinamide derivatives as DNA demethylase ALKBH2 inhibitors
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2025-01-01
err0
PREAI
errXu, Ke; Li, Feng; Xiong, Liang; Guo, Yinping; Zhang, Jian; Wang, Yuyang; Ji, Shanmian; Yang, Shengyong; Li, Linli
err分享
err收藏
Predicting transcriptional responses to novel chemical perturbations using deep generative model for drug discovery使用深度生成模型预测药物发现对新型化学扰动的转录反应
errNATURE COMMUNICATIONS
IF15.7
err2024-10-26
err0
errOAAI
errQi, Xiaoning; Zhao, Lianhe; Tian, Chenyu; Li, Yueyue; Chen, Zhen-Lin; Huo, Peipei; Chen, Runsheng; Liu, Xiaodong; Wan, Baoping; Yang, Shengyong; Zhao, Yi
err分享
err收藏
Structural Optimization and Structure-Activity Relationship of 1H-Pyrazole-4-carboxylic Acid Derivatives as DNA 6mA Demethylase ALKBH1 Inhibitors and Their Antigastric Cancer Activity
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-09-03
err0
PREAI
errLi, Feng; Xiong, Liang; Zhang, Jian; Guo, Yinping; Xu, Ke; Xiong, Zijie; Wang, Yuyang; Ji, Shanmian; Tong, Aiping; Li, Linli; Yang, Shengyong
err分享
err收藏
Structure- based identification of a G protein-biased allosteric modulator of cannabinoid receptor CB1基于结构的大麻素受体CB1的g蛋白偏向变构调节剂的鉴定
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-06-03
err3
errOAAI
errShen, Siyuan; Wu, Chao; Lin, Guifeng; Yang, Xin; Zhou, Yangli; Zhao, Chang; Miao, Zhuang; Tian, Xiaowen; Wang, Kexin; Yang, Zhiqian; Liu, Zhiyu; Guo, Nihong; Li, Yueshan; Xia, Anjie; Zhou, Pei; Liu, Jingming; Yan, Wei; Ke, Bowen; Yang, Shengyong; Shao, Zhenhua
err分享
err收藏
Identification of a new class of activators of the Hippo pathway with antitumor activity in vitro and in vivo
errBIOCHEMICAL PHARMACOLOGY
IF5.6
err2024-06-01
err0
PREAI
errLin, Guifeng; Xia, Anjie; Qiao, Jingxin; Zhang, Hailin; Chen, Pei; Zhou, Pei; Hu, Qian; Xiang, Zhiyu; Zhang, Shiyu; Li, Linli; Yang, Shengyong
err分享
err收藏
Inhibition of METTL3 Alleviates NLRP3 Inflammasome Activation via Increasing Ubiquitination of NEK7
errADVANCED SCIENCE
IF14.1
err2024-05-02
err6
errOAAI
errZhou, Xinyi; Yang, Xiaoyu; Huang, Shenzhen; Lin, Guifeng; Lei, Kexin; Wang, Qian; Lin, Weimin; Li, Hanwen; Qi, Xingying; Seriwatanachai, Dutmanee; Yang, Shengyong; Shao, Bin; Yuan, Quan
err分享
err收藏

研究方向

药物分子设计新方法研究小分子靶向药物设计合成与先导化合物优化研究化学生物学针对肿瘤自身免疫性疾病神经精神系统疾病感染性疾病等一类新药研究与开发
合作学者
合作期刊
K
Kwok‐Yung Yuen
H 指数: 161 · 论文数: 1.7K
S
Scott W. Lowe
H 指数: 156 · 论文数: 977
C
Christopher J. Schofield
H 指数: 112 · 论文数: 1.3K
Y
Yuquan Wei
H 指数: 111 · 论文数: 1.2K
杨
杨薇 (Wei Yang)
H 指数: 100 · 论文数: 1.1K
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