Heinrich C. Hoppe - Publications, H-index & Citations

Heinrich C. Hoppe

rhodes university

34H指数

184论文数

4.1K被引数

收录论文 55

发表时间

Effect of Stereochemistry on the Antiplasmodial Activity and Metabolomic Profile of Novel Tadalafil Analogues 立体化学对新型他达拉非类似物的抗疟疾活性和代谢组学特征的影响

ACS Medicinal Chemistry Letters

IF4

2026-04-14

PREAI

Esraa A. Elhalawaty; Howida A. Alseedy; John G. Woodland; Kathryn J. Wicht; Tarryn Swart; Gabriel W. Rangel; Heinrich C Hoppe; Kelly Chibale; Manuel Llinás; Ashraf H. Abadi; Nermin S. Ahmed

Acanthospermum australe Extract Inhibits the Chaperone Activity of Plasmodium falciparum Heat Shock Protein 70-1 Acanthospermum australe 提取物抑制了 Plasmodium falciparum 热休克蛋白 70-1 的分子伴侣活性。

Microorganisms 2025, Vol. 13, Page 2195

IF4.2

2025-09-27

OAAI

Ntombikhona Appear Koza; Ntokozo Nkosinathi Myeza; Heinrich Hoppe; Rebamang Anthony Mosa; Abidemi Paul Kappo; Mthokozisi Blessing Cedric Simelane; Andrew Rowland Opoku

Effects of seasonal variation on phytochemicals contributing to the antimalarial and antitrypanosomal activities of Breonadia salicina using a metabolomic approach

HELIYON

IF3.6

2024-01-01

OAAI

Tlhapi, Dorcas; Ramaite, Isaiah; Anokwuru, Chinedu; van Ree, Teunis; Madala, Ntakadzeni; Hoppe, Heinrich

Hydrazone-Tethered 5-(Pyridin-4-yl)-4H-1,2,4-triazole-3-thiol Hybrids: Synthesis, Characterisation, in silico ADME Studies, and in vitro Antimycobacterial Evaluation and Cytotoxicity

CHEMMEDCHEM

IF3.4

2023-01-30

OAAI

Oderinlo, Ogunyemi. O. O.; Jordaan, Audrey; Seldon, Ronnett; Isaacs, Michelle; Hoppe, Heinrich. C. C.; Warner, Digby. F. F.; Tukulula, Matshawandile; Khanye, Setshaba. D. D.

Synthesis and conformational studies of 5-bromo-1-[(N-substituted-carbamoyl)methyl]-7-azabenzimidazoles

JOURNAL OF MOLECULAR STRUCTURE

IF4.7

2022-12-01

PREAI

Oluwafemi, Kola A.; Klein, Rosalyn; Lobb, Kevin A.; Tshiwawa, Tendamudzimu; Isaacs, Michelle; Hoppe, Heinrich C.; Kaye, Perry T.

7H-Pyrrolo[2,3-d]pyrimidine-4-amines as Potential Inhibitors of Plasmodium falciparum Calcium-Dependent Protein Kinases 7h-吡咯并 [2，3-d] 嘧啶-4-胺作为恶性疟原虫钙依赖性蛋白激酶的潜在抑制剂

CHEMMEDCHEM

IF3.4

2022-09-29

OAAI

Seanego, Tswene D.; Chavalala, Hlamulo E.; Henning, Hendrik H.; de Koning, Charles B.; Hoppe, Heinrich C.; Ojo, Kayode K.; Rousseau, Amanda L.

Antiplasmodial Activity of Vachellia xanthophloea (Benth.) P.J.H. Hurter (African Fever Tree) and Its Constituents

PHARMACEUTICALS

IF4.8

2022-04-13

OAAI

Tajuddeen, Nasir; Swart, Tarryn; Hoppe, Heinrich C.; van Heerden, Fanie R.

Synthesis and in vitro antitrypanosomal evaluation of novel 6-heteroarylidene-substituted quinolone derivatives

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2022-01-01

PREAI

Angula, Klaudia T.; Legoabe, Lesetja J.; Swart, Tarryn; Hoppe, Heinrich C.; Beteck, Richard M.

Antiplasmodial and Cytotoxic Flavonoids from Pappea capensis (Eckl. & Zeyh.) Leaves

MOLECULES

IF4.6

2021-06-25

OAAI

Tajuddeen, Nasir; Swart, Tarryn; Hoppe, Heinrich C.; van Heerden, Fanie R.

Coumarin-Annulated Ferrocenyl 1,3-Oxazine Derivatives Possessing In Vitro Antimalarial and Antitrypanosomal Potency

MOLECULES

IF4.6

2021-03-02

OAAI

Mbaba, Mziyanda; Dingle, Laura M. K.; Zulu, Ayanda I.; Laming, Dustin; Swart, Tarryn; de la Mare, Jo-Anne; Hoppe, Heinrich C.; Edkins, Adrienne L.; Khanye, Setshaba D.

Easy-To-Access Quinolone Derivatives Exhibiting Antibacterial and Anti-Parasitic Activities

MOLECULES

IF4.6

2021-02-20

OAAI

Beteck, Richard M.; Jordaan, Audrey; Seldon, Ronnett; Laming, Dustin; Hoppe, Heinrich C.; Warner, Digby F.; Khanye, Setshaba D.

Potential repurposing of four FDA approved compounds with antiplasmodial activity identified through proteome scale computational drug discovery and in vitro assay

SCIENTIFIC REPORTS

IF3.9

2021-01-14

OAAI

Diallo, Bakary N'tji; Swart, Tarryn; Hoppe, Heinrich C.; Tastan Bishop, Oezlem; Lobb, Kevin

Virtual screening and in vitro validation identifies the first reported inhibitors of Salmonella enterica HPPK

RSC MEDICINAL CHEMISTRY

IF3.6

2021-01-01

OAAI

Mueller, Ronel; Gerwel, Tiaan M.; Kimuda, Magambo Phillip; Bishop, Ozlem Tastan; Veale, Clinton G. L.; Hoppe, Heinrich C.

In Vitro Studies on Antioxidant and Anti-Parasitic Activities of Compounds Isolated fromRauvolfia caffraSond

MOLECULES

IF4.6

2020-08-20

OAAI

Tlhapi, Dorcas B.; Ramaite, Isaiah D. I.; Anokwuru, Chinedu P.; van Ree, Teunis; Hoppe, Heinrich C.

6-Nitro-1-benzylquinolones exhibiting specific antitubercular activity

CHEMICAL BIOLOGY & DRUG DESIGN

IF3.3

2020-07-26

PREAI

Beteck, Richard M.; Jordaan, Audrey; Swart, Tarryn; Van der Kooy, Frank; Warner, Digby F.; Hoppe, Heinrich C.; Legoabe, Lesetja J.

Synthesis, Structure and In Vitro Anti-Trypanosomal Activity of Non-Toxic Arylpyrrole-Based Chalcone Derivatives

MOLECULES

IF4.6

2020-04-04

OAAI

Zulu, Ayanda I.; Oderinlo, Ogunyemi O.; Kruger, Cuan; Isaacs, Michelle; Hoppe, Heinrich C.; Smith, Vincent J.; Veale, Clinton G. L.; Khanye, Setshaba D.

Phytofabrication of Silver/Silver Chloride Nanoparticles Using Aqueous Leaf Extract of Oedera genistifolia: Characterization and Antibacterial Potential

MOLECULES

IF4.6

2019-11-30

OAAI

Okaiyeto, Kunle; Ojemaye, Mike O.; Hoppe, Heinrich; Mabinya, Leonard V.; Okoh, Anthony I.

Exploring the Antiplasmodial 2-Aminopyridines as Potential Antitrypanosomal Agents

CHEMMEDCHEM

IF3.4

2019-11-12

PREAI

Veale, Clinton G. L.; Laming, Dustin; Swart, Tarryn; Chibale, Kelly; Hoppe, Heinrich C.

Preparation and antiplasmodial activity of 3',4'-dihydro-1'H-spiro(indoline-3,2'-quinolin)-2-ones

CHEMICAL BIOLOGY & DRUG DESIGN

IF3.3

2019-08-27

PREAI

Mathebula, Bakolise; Butsi, Kamogelo Rosinah; van Zyl, Robyn Lynne; van Vuuren, Natasha Colleen Jansen; Hoppe, Heinrich Carl; Michael, Joseph Philip; de Koning, Charles Bernard; Rousseau, Amanda Louise

New Quinolone-Based Thiosemicarbazones Showing Activity Against Plasmodium falciparum and Mycobacterium tuberculosis

MOLECULES

IF4.6

2019-05-04

OAAI

Beteck, Richard M.; Seldon, Ronnett; Jordaan, Audrey; Warner, Digby F.; Hoppe, Heinrich C.; Laming, Dustin; Khanye, Setshaba D.

研究方向