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S

Shan Cen

chinese academy of medical sciences and peking union medical college

44H指数
297论文数
6.8K被引数
收录论文 134
发表时间
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An ELISA-Inspired Self-Propagating Click-Fluoresce-and-Release Assay for the Ultrasensitive Detection of CD13 in Lung Cancer Patient PlasmaELISA灵感启发的自传播点击-荧光-释放检测方法用于肺癌患者血浆中CD13的超灵敏检测
errAngewandte Chemie-International Edition
IF16.9
err2026-08-28
err0
PREAI
errMiao Liu; Dongguang Fan; Runhong Zhou; Wei Peng; Yan Huang; Shiping He; Fan Xu; Saisai Guo; Yongyou Wu; Shan Cen; Xingyue Ji
err分享
err收藏
New nonacyclic duclauxin derivatives with potent anti-influenza activities from Antarctic fungus Penicillium sp. CPCC 401065新型九环杜克索因衍生物及其源自南极真菌Penicillium sp. CPCC 401065的强效抗流感活性
errBioorganic Chemistry
IF4.7
err2026-04-16
err0
PREAI
errQingrong Du; Zhe Guo; Yujia Wang; Jun Hu; Jinglin Bai; Tao Zhang; Shan Cen; Jianyuan Zhao; Liyan Yu; Dewu Zhang
err分享
err收藏
Characterization of Storage-Induced mRNA Modifications in (4S)-KEL12 LNP: Adduct Formation Kinetics; mRNA Decay; and Translational Competence(4s)-KEL12 LNP中储存诱导的mRNA修饰的表征: 加合物形成动力学; mRNA衰变; 和翻译能力
errMolecular Pharmaceutics
IF4.5
err2026-02-04
err0
PREAI
errHua Chen; Jiaqi Gong; Wei Wu; Yanqin Shi; Juan Li; Zhenlei Yu; Hui Bao; Xu Ye; Tingting Zhang; Yijie Dong; Shan Cen; Kai Lv; Weiguo Zhang
err分享
err收藏
Mechanistic insights and therapeutic advances in antiviral strategies against African swine fever virus非洲猪瘟病毒抗病毒策略的作用机制见解和治疗进展
errActa Pharmaceutica Sinica B
IF14.6
err2025-12-23
err0
errOAAI
errHuihan Shao; Quanjie Li; Shan Cen
err分享
err收藏
SLFN14 functions as a P-TEFb inhibitor to modulate the transcription of HIV-1 and cellular genesSLFN14作为P-TEFb抑制剂，调节HIV-1和细胞基因的转录。
errScience Advances
IF12.5
err2025-12-17
err0
errOAAI
errShu-min Chen; Ling Ma; Zhen Wang; Quan-jie Li; Rui Zhou; Jing Wang; Ji-wei Ding; Jian-yuan Zhao; Dong-rong Yi; Yong-xin Zhang; Sai-sai Guo; Xin-lu Wang; Xiao-yu Li; Zhen-long Liu; Shan Cen
err分享
err收藏
The development of anti-HIV agents targeting APOBEC3G/Vif axis靶向APOBEC3G/Vif轴的HIV抑制剂开发
errBioorganic & Medicinal Chemistry
IF3
err2025-12-11
err0
PREAI
errQiqi Bao; Jiajia Wen; Fengjiao Xiang; Ling Ma; Jiwei Ding; Xinlu Wang; Shan Cen; Jinming Zhou
err分享
err收藏
Corrigendum to “Thiol esters as chemical warheads of SARS-CoV-2 main protease (3CLpro) peptide-like inhibitors” [Eur. J. Med. Chem. 293 (2025) 117709]勘误：硫醇酯作为SARS-CoV-2主蛋白酶（3CLpro）肽类抑制剂的化学弹头 [Eur. J. Med. Chem. 293 (2025) 117709]
errEuropean Journal of Medicinal Chemistry
IF5.9
err2025-12-10
err0
errOAAI
errXuehong Qiao; Menghan Cui; Zhiwei Yu; Ling Ma; Hailong Liu; Xingxing Yang; Yuan Chen; Dahong Li; Jinjing Che; Linxiang Zhao; Ruibin Su; Xuhong Ren; Shan Cen; Bin Lin; Xinhua He
err分享
err收藏
Identification of flavonoid-based small molecule inhibitors with dual-targeting capability against RdRp and Mpro of SARS-CoV-2鉴定具有双靶点能力的黄酮类小分子抑制剂，针对SARS-CoV-2的RdRp和Mpro
errBioorganic & Medicinal Chemistry Letters
IF2.2
err2025-12-08
err0
PREAI
errYanlei Su; Yujia Wang; Jianyuan Zhao; Keyu Guo; Xuhong Duan; Honghai Wu; Dianxing Sun; Jing Zhang; Shan Cen
err分享
err收藏
A potent and selective PROTAC degrader of CDK9 as effective inhibitor of HIV-1 RNA synthesis一种高效且特异性的CDK9 PROTAC降解剂，作为HIV-1 RNA合成的有效抑制剂
errMolecular Diversity
IF3.8
err2025-11-12
err0
PREAI
errBo Yang; Ling Ma; Xiaotang Yang; Jiajia Wen; Weiyi Yin; Siqi Li; Yingjie Ji; Ying Wang; Shan Cen; Yanping Li
err分享
err收藏
Design, Synthesis, and Biological Evaluation of Novel Core Scaffold-Modified HIV-1 Protease Inhibitors for Overcoming Drug Resistance
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2025-10-01
err0
PREAI
errZhou, Huiyu; Gao, Yu; Yang, Qingqing; Shan, Qi; Meng, Sihan; Ma, Ling; Dong, Biao; Wang, Juxian; Zhang, Guoning; Wang, Minghua; Cen, Shan; Wang, Yucheng; Che, Yongsheng; Zhu, Mei
err分享
err收藏
Neferine inhibits Zika virus replication by targeting viral proteaseNeferine通过靶向病毒蛋白酶抑制Zika病毒复制
errPhytomedicine
IF8.3
err2025-08-05
err0
PREAI
errSenfeng Sun; Tingting Sun; Xinyu Lei; Fangfei Li; Jing Wang; Rui Zhou; Quanjie Li; Dongrong Yi; Jing Wang; Hongwei Jin; Shan Cen; Shizhong Chen
err分享
err收藏
Rational design, synthesis, and evaluating primary biological activities of novel HIV-1 protease inhibitors containing heteraryl acetamides as the P2 ligands理性设计、合成及评价含杂芳基乙酰胺作为P2配体的新型HIV-1蛋白酶抑制剂的初步生物活性
errBioorganic & Medicinal Chemistry
IF3
err2025-08-05
err0
PREAI
errSihan Meng; Yu Gao; Qingqing Yang; Ling Ma; Biao Dong; Juxian Wang; Guoning Zhang; Minghua Wang; Shan Cen; Mei Zhu; Qi Shan; Yucheng Wang
err分享
err收藏
Host lncRNA assists the nuclear import of influenza A virus protein PB2 in a species-specific manner宿主lncRNA以种属特异性方式协助流感A病毒蛋白PB2的核内转运。
errJournal of Infection
IF11.9
err2025-06-23
err0
errOAAI
errJing Wang; Saisai Guo; Jianyuan Zhao; Tingting Sun; Yilu Ye; Rui Zhou; Tao Deng; Xiaoyu Li; Jianwei Wang; Shan Cen
err分享
err收藏
Discovery and rational optimization of 2, 2′-((1H-indole-2,3-diyl) bis (thio)) diacetamide as novel SARS-CoV-2 RdRp inhibitors
errBIOORGANIC & MEDICINAL CHEMISTRY
IF3
err2025-06-01
err0
PREAI
errShi, Yu; Zhao, Jianyuan; Li, Min; Wei, Liya; Shan, Qi; Wang, Minghua; Zhu, Mei; Cen, Shan; Zhang, Guoning; Wang, Juxian; Wang, Yucheng
err分享
err收藏
Thiol esters as chemical warheads of SARS-CoV-2 main protease (3CLpro) peptide-like inhibitors硫醇酯作为SARS-CoV-2主蛋白酶（3CLpro）肽样抑制剂的化学弹头
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2025-05-28
err0
PREAI
errQiao, Xuehong; Cui, Menghan; Yu, Zhiwei; Ma, Ling; Liu, Hailong; Yang, Xingxing; Chen, Yuan; Li, Dahong; Che, Jinjing; Zhao, Linxiang; Su, Ruibin; Ren, Xuhong; Cen, Shan; Lin, Bin; He, Xinhua
err分享
err收藏
IncRNA IPAN antagonizes RIG-I/TRIM25-mediated degradation of influenza A virus PB1 to promote viral replication长链非编码RNA IPAN拮抗RIG-I/TRIM25介导的甲型流感病毒PB1的降解，以促进病毒复制
errBiosafety and Health
IF3
err2025-05-17
err0
errOAAI
errTingting Sun; Shumin Chen; Rui Zhou; Saisai Guo; Yilu Ye; Jingyi Qiu; Xiaoyu Li; Shan Cen; Jing Wang
err分享
err收藏
Aspversols A-H, monomeric and dimeric phenolic bisabolane sesquiterpenoids with antiviral and cytotoxic activities from polar moss-derived fungus Aspergillus sp. CPCC 401664Aspversols A-H，来自极地苔藓来源真菌Aspergillus sp. CPCC 401664的单聚体和二聚体酚类bisabolane倍半萜，具有抗病毒和细胞毒性活性
errPHYTOCHEMISTRY
IF3.4
err2025-05-14
err0
PREAI
errDu, Qingrong; Chen, Ming; Liu, Yu; Ma, Ling; Bai, Jinglin; Hu, Jun; Zhang, Tao; Cen, Shan; Wang, Fang; Yu, Liyan
err分享
err收藏
Synthesis and biological evaluation of substituted quinolines containing piperazine moieties against Influenza A virus含哌嗪基团的取代喹啉的合成与抗流感A病毒的生物评价
errBIOORGANIC & MEDICINAL CHEMISTRY LETTERS
IF2.2
err2025-04-01
err0
PREAI
errLi, Hongxuan; Zhao, Jianyuan; Jiang, Fangyi; Zheng, Chenghong; Zhang, Guoning; Zhu, Mei; Cen, Shan; Wang, Minghua; Wang, Yucheng; Wang, Juxian
err分享
err收藏
Novel virulence determinants in VP1 regulate the assembly of enterovirus-A71
errJOURNAL OF VIROLOGY
IF3.8
err2024-12-17
err0
PREAI
errZhang, Wenjing; Li, Quanjie; Yi, Dongrong; Zheng, Ruifang; Liu, Guihua; Liu, Qian; Guo, Saisai; Zhao, Jianyuan; Wang, Jing; Ma, Ling; Ding, Jiwei; Zhou, Rui; Ren, Yongcheng; Sun, Tingting; Zhang, Ao; Li, Xiaoyu; Zhang, Yongxin; Cen, Shan
err分享
err收藏
Protection efficacy of mRNA-based SARS-CoV-2 variant vaccine in non-human primates基于mRNA的SARS-CoV-2变异株疫苗在非人灵长类动物中的保护效力
errACTA PHARMACEUTICA SINICA B
IF14.6
err2024-12-01
err0
errOAAI
errYi, DR; Zhang, YX; Wang, J; Liu, Q; Ma, L; Li, QJ; Guo, SS; Zheng, RF; Li, XY; Li, XG; Dong, YJ; Lu, SY; Zhang, WG; Peng, XZ; Cen, S
err分享
err收藏

研究方向

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合作学者
合作期刊
G
George F. Gao
H 指数: 135 · 论文数: 1.2K
G
Gary J. Nabel
H 指数: 133 · 论文数: 507
P
Paul K.S. Chan
H 指数: 99 · 论文数: 802
魏琴 封面图
魏琴 (Qin Wei)
H 指数: 98 · 论文数: 1.3K
刘
刘威 (Wei Liu)
H 指数: 95 · 论文数: 1.8K
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