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In vivo screen of Plasmodium targets for mosquito-based malaria control 基于蚊媒疟疾控制的疟原虫体内靶点筛选 Probst, Alexandra S.; Paton, Douglas G.; Appetecchia, Federico; Bopp, Selina; Adams, Kelsey L.; Rinvee, Tasneem A.; Pou, Sovitj; Winter, Rolf; Du, Esrah W.; Yahiya, Sabrina; Vidoudez, Charles; Singh, Naresh; Rodrigues, Janneth; Castaneda-Casado, Pablo; Tammaro, Chiara; Chen, Daisy; Godinez-Macias, Karla P.; Jaramillo, Jasmine L.; Poce, Giovanna; Rubal, Michael J.; Nilsen, Aaron; Winzeler, Elizabeth A.; Baum, Jake; Burrows, Jeremy N.; Riscoe, Michael K.; Wirth, Dyann F.; Catteruccia, Flaminia 分享 收藏
CRISPR/Cas9-engineering of Kell null erythrocytes to unveil host targeted irresistible antimalarial 利用CRISPR/Cas9技术改造Kell阴性红细胞以揭示靶向宿主的不易受抗疟机制 Kumari, Geeta; Gupta, Pragya; Goswami, Sangam G.; Jain, Ravi; Anand, Sakshi; Biswas, Shreeja; Garg, Swati; Thakur, Priya; Saravanakumar, Vinodh; Arvinden, V. R.; Goswami, Bidhan; Bhowmick, Ipsita Pal; Mohandas, Narla; Burrows, Jeremy; Ramalingam, Sivaprakash; Singh, Shailja 分享 收藏
Anopheles mosquito survival and pharmacokinetic modeling show the mosquitocidal activity of nitisinone 按蚊生存及药代动力学模型显示，nitisinone具有杀蚊活性。 Haines, Lee R.; Trett, Anna; Rose, Clair; Garcia, Natalia; Sterkel, Marcos; Mcguinness, Dagmara; Regnault, Clement; Barrett, Michael P.; Leroy, Didier; Burrows, Jeremy N.; Biagini, Giancarlo; Ranganath, Lakshminarayan R.; Aljayyoussi, Ghaith; Acosta-Serrano, Alvaro 分享 收藏
Inhibitors of malaria parasite cyclic nucleotide phosphodiesterases block asexual blood-stage development and mosquito transmission Gomez-Gonzalez, Paula-Josefina; Gupta, Antima; Drought, Laura G.; Patel, Avnish; Okombo, John; van der Watt, Mariette; Walker-Gray, Ryan; Schindler, Kyra A.; Burkhard, Anna Y.; Yeo, Tomas; Narwal, Sunil K.; Bloxham, Talia S.; Flueck, Christian; Walker, Eloise M.; Rey, Joshua A.; Fairhurst, Kate J.; Reader, Janette; Park, Heekuk; Pollard, Harry G.; Stewart, Lindsay B.; Brandner-Garrod, Luke; Kristan, Mojca; Sterk, Geert-Jan; van Nuland, Youri M.; Manko, Emilia; van Schalkwyk, Donelly A.; Zheng, Yang; Leurs, Rob; Dechering, Koen J.; Aguiar, Anna Caroline C.; Guido, Rafael V. C.; Pereira, Dhelio B.; Tumwebaze, Patrick K.; Nosbya, Samuel L.; Rosenthal, Philip J.; Cooper, Roland A.; Palmer, Mike; Parkinson, Tanya; Burrows, Jeremy N.; Uhlemann, Anne-Catrin; Birkholtz, Lyn-Marie; Small-Saunders, Jennifer L.; Duffy, James; Fidock, David A.; Brown, Alan; Gardner, Mark; Baker, David A. 分享 收藏
Tambjamines as Fast-Acting Multistage Antimalarials Kumar, Amrendra; Li, Yuexin; Dodean, Rozalia A.; Roth, Alison; Caridha, Diana; Madejczyk, Michael S.; Jin, Xiannu; Dennis, William E.; Lee, Patricia J.; Pybus, Brandon S.; Martin, Monica; Pannone, Kristina; Dinh, Hieu T.; Blount, Cameron; Chetree, Ravi; Deluca, Jesse; Evans, Martin; Nadeau, Robert; Vuong, Chau; Leed, Susan; Black, Chad; Sousa, Jason; Nolan, Christina; Ceja, Frida G.; Rasmussen, Stephanie A.; Tumwebaze, Patrick K.; Rosenthal, Philip J.; Cooper, Roland A.; Rottmann, Matthias; Orjuela-Sanchez, Pamela; Meister, Stephan; Winzeler, Elizabeth A.; Delves, Michael J.; Matthews, Holly; Baum, Jake; Kirby, Robert W.; Burrows, Jeremy N.; Duffy, James; Peyton, David H.; Reynolds, Kevin A.; Kelly, Jane X.; Kancharla, Papireddy 分享 收藏
Global Health Priority Box-Proactive Pandemic Preparedness Adam, Anna; Besson, Dominique; Bryant, Rob; Rees, Sarah; Willis, Paul A.; Burrows, Jeremy N.; van Huisjduijnen, Rob Hooft; Laleu, Benoit; Norton, Larry; Canan, Stacie; Hawryluk, Natalie; Robinson, Dale; Palmer, Mike; Samby, Kirandeep Kaur 分享 收藏
Discovery of 1,3,4-oxadiazoles with slow-action activity against Plasmodium falciparum malaria parasites Andrews, Katherine T.; Fisher, Gillian M.; Firmin, Meaghan; Liepa, Andris J.; Wilson, Tony; Gardiner, James; Mohri, Yacine; Debele, Emmanuel; Rai, Anjana; Davey, Andrew K.; Masurier, Antoine; Delion, Alix; Mouratidis, Alexandros A.; Hutt, Oliver E.; Forsyth, Craig M.; Burrows, Jeremy N.; Ryan, John H.; Riches, Andrew G.; Skinner-Adams, Tina S. 分享 收藏
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Protein target similarity is positive predictor of in vitro antipathogenic activity: a drug repurposing strategy for Plasmodium falciparum Mogire, Reagan M.; Miruka, Silviane A.; Juma, Dennis W.; McNamara, Case W.; Andagalu, Ben; Burrows, Jeremy N.; Chenu, Elodie; Duffy, James; Ogutu, Bernhards R.; Akala, Hoseah M. 分享 收藏
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Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase Xie, Stanley C.; Wang, Yinuo; Morton, Craig J.; Metcalfe, Riley D.; Dogovski, Con; Pasaje, Charisse Flerida A.; Dunn, Elyse; Luth, Madeline R.; Kumpornsin, Krittikorn; Istvan, Eva S.; Park, Joon Sung; Fairhurst, Kate J.; Ketprasit, Nutpakal; Yeo, Tomas; Yildirim, Okan; Bhebhe, Mathamsanqa N.; Klug, Dana M.; Rutledge, Peter J.; Godoy, Luiz C.; Dey, Sumanta; De Souza, Mariana Laureano; Siqueira-Neto, Jair L.; Du, Yawei; Puhalovich, Tanya; Amini, Mona; Shami, Gerry; Loesbanluechai, Duangkamon; Nie, Shuai; Williamson, Nicholas; Jana, Gouranga P.; Maity, Bikash C.; Thomson, Patrick; Foley, Thomas; Tan, Derek S.; Niles, Jacquin C.; Han, Byung Woo; Goldberg, Daniel E.; Burrows, Jeremy; Fidock, David A.; Lee, Marcus C. S.; Winzeler, Elizabeth A.; Griffin, Michael D. W.; Todd, Matthew H.; Tilley, Leann 分享 收藏
MAIP: An Open-Source Tool to Enrich High-Throughput Screening Output and Identify Novel, Druglike Molecules with Antimalarial Activity Bosc, Nicolas; Felix, Eloy; Gardner, J. Mark F.; Mills, James; Timmerman, Martijn; Asveld, Dennis; Rensen, Kim; Mukherjee, Partha; Das, Rishi; Chenu, Elodie; Besson, Dominique; Burrows, Jeremy N.; Duffy, James; Laleu, Benoit; Guantai, Eric M.; Leach, Andrew R. 分享 收藏
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Development and application of a PBPK modeling strategy to support antimalarial drug development Abla, Nada; Howgate, Eleanor; Rowland-Yeo, Karen; Dickins, Maurice; Bergagnini-Kolev, Mackenzie C. C.; Chen, Kuan-Fu; McFeely, Savannah; Bonner, Jennifer J. J.; Santos, Laura G. A.; Gobeau, Nathalie; Burt, Howard; Barter, Zoe; Jones, Hannah M. M.; Wesche, David; Charman, Susan A. A.; Moehrle, Jorg J.; Burrows, Jeremy N. N.; Almond, Lisa M. M. 分享 收藏
The Parasite Reduction Ratio (PRR) Assay Version 2: Standardized Assessment of Plasmodium falciparum Viability after Antimalarial Treatment In Vitro Walz, Annabelle; Duffey, Maelle; Aljayyoussi, Ghaith; Sax, Sibylle; Leroy, Didier; Besson, Dominique; Burrows, Jeremy N.; Cherkaoui-Rbati, Mohammed H.; Gobeau, Nathalie; Westwood, Marie-Anne; Siethoff, Christoph; Gamo, Francisco-Javier; Maser, Pascal; Wittlin, Sergio 分享 收藏
'Erythritol', a safe natural sweetener exhibits multi-stage anti-malarial activity by permeating into Plasmodium falciparum through aquaglyceroporin channel Kumari, Jyoti; Kumar, Vikash; Behl, Ankita; Sah, Raj Kumar; Kumari, Geeta; Garg, Swati; Gupta, Aashima; Mohaideen, S. Nazar Mohomed; Shafi, Sadat; Pati, Soumya; Samby, Kirandeep; Burrows, Jeremy; Mohandas, Narla; Singh, Shailja 分享 收藏
Discovery and Characterization of Potent, Efficacious, Orally Available Antimalarial Plasmepsin X Inhibitors and Preclinical Safety Assessment of UCB7362 有效，有效，口服可用的抗疟血浆蛋白酶X抑制剂的发现和表征以及UCB7362的临床前安全性评估 Lowe, Martin A. .; Cardenas, Alvaro; Valentin, Jean-Pierre; Zhu, Zhaoning; Abendroth, Jan; Castro, Jose L.; Class, Reiner; Delaunois, Annie; Fleurance, Renaud; Gerets, Helga; Gryshkova, Vitalina; King, Lloyd; Lorimer, Donald D.; MacCoss, Malcolm; Rowley, Julian H.; Rosseels, Marie-Luce; Royer, Leandro; Taylor, Richard D.; Wong, Melanie; Zaccheo, Oliver; Chavan, Vishal P.; Ghule, Gokul A. .; Tapkir, Bapusaheb K.; Burrows, Jeremy N.; Duffey, Maelle; Rottmann, Matthias; Wittlin, Sergio; Angulo-Barturen, Inigo; Belen Jimenez-Diaz, Maria; Striepen, Josefine; Fairhurst, Kate J.; Yeo, Tomas; Fidock, David A. .; Cowman, Alan F.; Favuzza, Paola; Crespo-Fernandez, Benigno; Javier Gamo, Francisco; Goldberg, Daniel E.; Soldati-Favre, Dominique; Laleu, Benoit; de Haro, Teresa 分享 收藏
Multistage and transmission-blocking tubulin targeting potent antimalarial discovered from the open access MMV pathogen box Kumari, Geeta; Jain, Ravi; Sah, Kumar; Kalia, Inderjeet; Vashistha, Manu; Singh, Pooja; Singh, Agam Prasad; Samby, Kirandeep; Burrows, Jeremy; Singh, Shailja 分享 收藏
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