Dinghai Zheng - Publications, H-index & Citations

Dinghai Zheng

amgen

27H指数

61论文数

3.2K被引数

收录论文 32

发表时间

Optimizing Bispecific Antibody Expression via Multi-Omics Analysis and Vector Redesign 通过多组学分析和载体重设计优化双特异性抗体表达

Biotechnology and Bioengineering

IF3.6

2026-05-01

PREAI

Gam, Jeremy J.; Chang, Michelle M.; Zheng, Dinghai; Stevens, Jennitte; Nielsen, Alec A. K.; Smith, Kevin D.

Decoding the language of messenger RNA 解码信使RNA的语言

Nature Methods

IF32.1

2026-04-17

PREAI

Jun Wang; Dinghai Zheng; Vikram Agarwal

Identification of computationally designed skeletal and cardiac promoters with high specificity across AAV delivery routes 鉴定在腺相关病毒（AAV）递送途径中具有高特异性的计算设计的骨骼肌和心肌启动子

BMC Biotechnology

IF3.4

2026-03-26

OAAI

Nicole Zielinska; Erin L. Howard; Brenna A. Y. Stevens; Melanie M. Goens; Cici Yang; Elena S. B. Campbell; Madison E. Hughes; Yanlong Pei; Dinghai Zheng; D. Benjamin Gordon; Alec A. K. Nielsen; Raja R. Srinivas; Jeff L. Caswell; Luis G. Arroyo; Sarah K. Wootton

Predicting the translation efficiency of messenger RNA in mammalian cells 预测哺乳动物细胞中信使RNA的翻译效率

Nature Biotechnology

IF41.7

2025-07-25

OAAI

Dinghai Zheng; Logan Persyn; Jun Wang; Yue Liu; Fernando Ulloa-Montoya; Can Cenik; Vikram Agarwal

mRNA-LM: full-length integrated SLM for mRNA analysis mRNA-LM：用于mRNA分析的完整长度集成SLM

NUCLEIC ACIDS RESEARCH

IF13.1

2025-02-03

OAAI

Li, Sizhen; Noroozizadeh, Shahriar; Moayedpour, Saeed; Kogler-Anele, Lorenzo; Xue, Zexin; Zheng, Dinghai; Montoya, Fernando Ulloa; Agarwal, Vikram; Jager, Sven

Light regulates widespread plant alternative polyadenylation through the chloroplast 光通过叶绿体调控植物中广泛存在的选择性多聚腺苷酸化。

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-08-16

OAAI

Kubaczka, M. Guillermina; Herz, Micaela A. Godoy; Chen, Wei- Chun; Zheng, Dinghai; Tan, Bin; Kornblihtt, Alberto R.

CodonBERT large language model for mRNA vaccines mRNA疫苗的CodonBERT大语言模型

GENOME RESEARCH

IF5.5

2024-07-01

PREAI

Li, Sizhen; Moayedpour, Saeed; Li, Ruijiang; Bailey, Michael; Riahi, Saleh; Kogler-Anele, Lorenzo; Miladi, Milad; Miner, Jacob; Pertuy, Fabien; Zheng, Dinghai; Wang, Jun; Balsubramani, Akshay; Tran, Khang; Zacharia, Minnie; Wu, Monica; Gu, Xiaobo; Clinton, Ryan; Asquith, Carla; Skaleski, Joseph; Boeglin, Lianne; Chivukula, Sudha; Dias, Anusha; Strugnell, Tod; Montoya, Fernando Ulloa; Agarwal, Vikram; Bar-Joseph, Ziv; Jager, Sven

Human TOB, an antiproliferative transcription factor, is a poly(A)-binding protein-dependent positive regulator of cytoplasmic mRNA deadenylation

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

150

OAAI

Ezzeddine, Nader; Chang, Tsung-Cheng; Zhu, Wenmiao; Yamashita, Akio; Chen, Chyi-Ying A.; Zhong, Zhenping; Yamashita, Yukiko; Zheng, Dinghai; Shyu, Ann-Bin

The androgen receptor couples promoter recruitment of RNA processing factors to regulation of alternative polyadenylation at the 3' end of transcripts

NUCLEIC ACIDS RESEARCH

IF13.1

2022-08-31

OAAI

Caggiano, Cinzia; Pieraccioli, Marco; Pitolli, Consuelo; Babini, Gabriele; Zheng, Dinghai; Tian, Bin; Bielli, Pamela; Sette, Claudio

MAAPER: model-based analysis of alternative polyadenylation using 3′ end-linked reads

GENOME BIOLOGY

IF9.4

2021-08-10

OAAI

Li, Wei Vivian; Zheng, Dinghai; Wang, Ruijia; Tian, Bin

Alternative 3′ UTRs play a widespread role in translation-independent mRNA association with the endoplasmic reticulum

CELL REPORTS

IF6.9

2021-07-01

OAAI

Cheng, Larry C.; Zheng, Dinghai; Zhang, Qiang; Guvenek, Aysegul; Cheng, Hong; Tian, Bin

A CRISPR RNA-binding protein screen reveals regulators of RUNX1 isoform generation

BLOOD ADVANCES

IF7.1

2021-03-03

OAAI

Davis, Amanda G.; Einstein, Jaclyn M.; Zheng, Dinghai; Jayne, Nathan D.; Fu, Xiang-Dong; Tian, Bin; Yeo, Gene W.; Zhang, Dong-Er

3′READS plus RIP defines differential Staufen1 binding to alternative 3′UTR isoforms and reveals structures and sequence motifs influencing binding and polysome association

RNA

IF5

2020-08-12

OAAI

Zheng, Dinghai; Cho, Hana; Wang, Wei; Rambout, Xavier; Tian, Bin; Maquat, Lynne E.

Widespread transcript shortening through alternative polyadenylation in secretory cell differentiation

NATURE COMMUNICATIONS

IF15.7

2020-06-23

OAAI

Cheng, Larry C.; Zheng, Dinghai; Baljinnyam, Erdene; Sun, Fangzheng; Ogami, Koichi; Yeung, Percy Luk; Hoque, Mainul; Lu, Chi-Wei; Manley, James L.; Tian, Bin

The mRNA Export Receptor NXF1 Coordinates Transcriptional Dynamics, Alternative Polyadenylation, and mRNA Export

MOLECULAR CELL

IF16.6

2019-04-01

OAAI

Chen, Suli; Wang, Ruijia; Zheng, Dinghai; Zhang, Heng; Chang, Xingya; Wang, Ke; Li, Wencheng; Fan, Jing; Tian, Bin; Cheng, Hong

ALYREF links 3-end processing to nuclear export of non-polyadenylated mRNAs ALYREF将3端加工与非聚腺苷酸化mrna的核输出联系起来

EMBO JOURNAL

IF8.3

2019-03-12

OAAI

Fan, Jing; Wang, Ke; Du, Xian; Wang, Jianshu; Chen, Suli; Wang, Yimin; Shi, Min; Zhang, Li; Wu, Xudong; Zheng, Dinghai; Wang, Changshou; Wang, Lantian; Tian, Bin; Li, Guohui; Zhou, Yu; Cheng, Hong

Regulation of Intronic Polyadenylation by PCF11 Impacts mRNA Expression of Long Genes

CELL REPORTS

IF6.9

2019-03-01

OAAI

Wang, Ruijia; Zheng, Dinghai; Wei, Lu; Ding, Qingbao; Tian, Bin

A compendium of conserved cleavage and polyadenylation events in mammalian genes

GENOME RESEARCH

IF5.5

2018-08-24

OAAI

Wang, Ruijia; Zheng, Dinghai; Yehia, Ghassan; Tian, Bin

Cellular stress alters 3′UTR landscape through alternative polyadenylation and isoform-specific degradation

NATURE COMMUNICATIONS

IF15.7

2018-06-11

OAAI

Zheng, Dinghai; Wang, Ruijia; Ding, Qingbao; Wang, Tianying; Xie, Bingning; Wei, Lu; Zhong, Zhaohua; Tian, Bin

Activity-Dependent Regulation of Alternative Cleavage and Polyadenylation During Hippocampal Long-Term Potentiation

SCIENTIFIC REPORTS

IF3.9

2017-12-12

OAAI

Fontes, Mariana M.; Guvenek, Aysegul; Kawaguchi, Riki; Zheng, Dinghai; Huang, Alden; Ho, Victoria M.; Chen, Patrick B.; Liu, Xiaochuan; O'Dell, Thomas J.; Coppola, Giovanni; Tian, Bin; Martin, Kelsey C.

研究方向