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S

Stanislav Gobec

University of Porto

51H指数
500论文数
9.4K被引数
收录论文 190
发表时间
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Development of a 3-Amino-1-carboxymethyl-β-lactam-Based Monocyclic Ceftobiprole Analog基于3-氨基-1-羧甲基-β-内酰胺的单环头孢吡普类似物的开发
errChemistry-An Asian Journal
IF3.3
err2026-09-08
err0
PREAI
errKato Bredael; Martina Hrast Rambaher; Lena Decuyper; Katarina Magdalenic; Stanislav Gobec; Matthias D'hooghe
err分享
err收藏
Fragment-Based Design of Targeted Covalent Inhibitors: The Scope and Limitation of Linking Approaches靶向共价抑制剂的片段基设计：连接策略的适用范围与局限性
errChemMedChem
IF3.4
err2026-05-22
err0
errOAAI
errLevente Kollár; Levente M. Mihalovits; Dávid Bajusz; Damijan Knez; József Simon; Blake H. Balcomb; Daren Fearon; Stanislav Gobec; György M. Keserű
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Structure–Activity Relationship and Crystallographic Study of New Monobactams新型单生物的构效关系和晶体学研究
errJournal of Medicinal Chemistry
IF6.8
err2026-02-03
err0
errOAAI
errVid Kavaš; Carlos Contreras-Martel; Stane Pajk; Damijan Knez; Alexandre Martins; Thomas A. Gould; David I. Roper; Irena Zdovc; Andréa Dessen; Martina Hrast Rambaher; Stanislav Gobec
err分享
err收藏
α-Aminoboronic Acid Moieties in Boro Dipeptides Modulate Proteasome Subunit Selectivity and Provide Access to Compounds with Potent Anticancer and Anti-Inflammatory Activity
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2025-12-01
err0
PREAI
errStrasek Benedik, Nika; Sterman, Andrej; Smrdel, Lara; Pajk, Stane; Gobec, Stanislav; Casar, Zdenko; Gobec, Martina; Sosic, Izidor
err分享
err收藏
Expanding the reactive chemistry toolbox – warhead screening for covalent butyrylcholinesterase inhibitors拓展反应化学工具箱——用于共价丁酰胆碱酯酶抑制剂的战争头筛选
errChemico-Biological Interactions
IF5.4
err2025-11-21
err0
errOAAI
errAnže Meden; Xavier Brazzolotto; José Dias; Jure Stojan; Damijan Knez; Stanislav Gobec
err分享
err收藏
Dual Cholinergic Modulation in Dementia: Quinuclidine Carbamates Targeting Butyrylcholinesterase and α7 Nicotinic Receptor痴呆症的双胆碱能调节：靶向丁酰胆碱酯酶和α7烟碱型受体喹啉环碳酸酯类化合物
errChemico-Biological Interactions
IF5.4
err2025-11-15
err0
PREAI
errPeter Mastnak-Sokolov; Damijan Knez; Anže Meden; Nika Strašek Benedik; Svit Ferjančič Benetik; Martina Hrast Rambaher; Maša Zorman; Florian Nachon; Xavier Brazzolotto; Kent Jardemark; Oscar Jungholm; Joseph Bruton; Emilia Strandback; Tomas Nyman; Mohammed Shahid; Stanislav Gobec
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Targeting cystatin F activation enhances NK cell cytotoxicity in glioblastoma models靶向cystatin F激活可增强NK细胞在胶质母细胞瘤模型中的细胞毒性。
errFrontiers in Immunology
IF5.9
err2025-10-28
err0
errOAAI
errEmanuela Senjor; Anamarija Habič; Urban Švajger; Ana Mitrović; Matic Proj; Andrej Porčnik; Borut Prestor; Miha Jerala; Matic Bošnjak; Stanislav Gobec; Barbara Breznik; Janko Kos; Milica Perišić Nanut
err分享
err收藏
N-Methyl-N-((1-methyl-5-(3-(piperidin-1-yl)propoxy)-1H-benzo[d]imidazol-2-yl)methyl)prop-2-yn-1-amine (MBA-159), a new multitarget small molecule for the therapy of Alzheimer’s diseaseN-Methyl-N-((1-甲基-5-(3-(哌啶-1-基)丙氧基)-1H-苯并[d]咪唑-2-基)甲基)丙-2-炔-1-胺 (MBA-159)，一种用于阿尔茨海默病治疗的新型多靶点小分子
errBiomedicine & Pharmacotherapy
IF7.5
err2025-09-27
err0
errOAAI
errÓscar M. Bautista-Aguilera; Aleksandra Manik; Daniel Diez-Iriepa; Natalia Szałaj; Paula Zaręba; Anna Więckowska; Paweł Żmudzki; Ewelina Honkisz-Orzechowska; Damijan Knez; Stanislav Gobec; Kinga Sałat; Borja Martínez-Alonso; Víctor Guarnizo-Herrero; Guillermo Torrado Durán; Carlos Torrado-Salmerón; Aina Bellver-Sanchis; Inaya Nsiona-Defise; Marta Ribalta-Vilella; Mercè Pallàs; Francisco López-Muñoz; Christian Griñán-Ferré; José Marco-Contelles; Isabel Iriepa
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Transforming Ureas into carbamates: From allosteric p38α MAPK ligands to dual BChE/p38α MAPK inhibitors将脲类转化为氨基甲酸酯：从别构p38α MAPK配体到双重BChE/p38α MAPK抑制剂
errBioorganic Chemistry
IF4.7
err2025-09-16
err0
errOAAI
errSvit Ferjančič Benetik; Anže Meden; Damijan Knez; Peter Mastnak-Sokolov; Urban Košak; Selena Horvat; Anja Pišlar; Rudolf Andrys; Kamil Musílek; Jan Detka; Kinga Sałat; Aleš Obreza; Stanislav Gobec
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N-Propargylpyrrolidine-based butyrylcholinesterase and monoamine oxidase inhibitorsN-丙炔基吡咯烷基类丁酰胆碱酯酶和单胺氧化酶抑制剂
errChemico-Biological Interactions
IF5.4
err2025-07-30
err0
errOAAI
errUrban Košak; Damijan Knez; Anja Pišlar; Selena Horvat; Simon Žakelj; Alexandre Igert; José Dias; Florian Nachon; Xavier Brazzolotto; Stanislav Gobec
err分享
err收藏
Chiral switch of a butyrylcholinesterase inhibitor for the treatment of Alzheimer's disease丁酰胆碱酯酶抑制剂治疗阿尔茨海默病的对映异构体转换
errChemico-Biological Interactions
IF5.4
err2025-07-23
err0
PREAI
errUrban Košak; Damijan Knez; Svit Ferjančič Benetik; Peter Mastnak Sokolov; Anja Pišlar; Selena Horvat; Jure Stojan; Bingbing Lv; Weiting Zhang; Yuanyuan Wang; Qinjie Wang; Alexandre Igert; José Dias; Florian Nachon; Xavier Brazzolotto; Haopeng Sun; Stanislav Gobec
err分享
err收藏
Pleiotropic prodrugs for both symptomatic and disease-modifying treatment of Alzheimer’s disease多效性前药，用于治疗阿尔茨海默病的对症治疗和疾病修正治疗
errActa Pharmaceutica Sinica B
IF14.6
err2025-07-07
err0
errOAAI
errAnže Meden; Neža Žnidaršič; Damijan Knez; Yuanyuan Wang; Ziwei Xu; Huajing Yang; Weiting Zhang; Anja Pišlar; Andrej Perdih; Simona Kranjc Brezar; Neža Grgurevič; Stane Pajk; Haopeng Sun; Stanislav Gobec
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Repurposing of compound libraries yields new inhibitors of NDM-1 metallo-β-lactamase with diverse zinc-binding moieties化合物库的重新利用产生了针对NDM-1金属β-内酰胺酶的新型抑制剂，其锌结合基团具有多样性。
errEuropean Journal of Medicinal Chemistry Reports
IF4.1
err2025-06-19
err0
errOAAI
errVid Kavaš; Philip Hinchliffe; Maša Zorman; Alen Krajnc; Matic Proj; Majda Golob; Martina Hrast Rambaher; James Spencer; Stanislav Gobec
err分享
err收藏
Facile Synthesis of Carbamoyl Fluorides via N-Carbamoylimidazole Activation
errACS OMEGA
IF4.3
err2025-02-14
err0
errOAAI
errMeden, Anze; Knez, Damijan; Gobec, Stanislav
err分享
err收藏
Synthesis and Antibacterial Properties of 3-Amino-β-Lactams Bearing a Heteroatom-Containing C4 Substituent
errCHEMMEDCHEM
IF3.4
err2025-02-05
err0
PREAI
errBredael, Kato; Vanhecke, Fien; Vandenheede, Emma; Stevens, Christian V.; Gobec, Stanislav; D'hooghe, Matthias
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Dual inhibition of butyrylcholinesterase and p38α mitogen-activated protein kinase: A new approach for the treatment of Alzheimer's disea se
errPHARMACOLOGY & THERAPEUTICS
IF12.5
err2024-12-01
err0
errOAAI
errBenetik, Svit Ferjancic; Knez, Damijan; Obreza, Ales; Kosak, Urban; Gobec, Stanislav
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Contribution of direct InhA inhibitors to novel drug regimens in a mouse model of tuberculosis
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2024-11-06
err1
errOAAI
errEncinas, Lourdes; Li, Si-Yang; Rullas-Trincado, Joaquin; Tasneen, Rokeya; Tyagi, Sandeep; Soni, Heena; Garcia-Perez, Adolfo; Lee, Jin; del Rio, Ruben Gonzalez; De Mercado, Jaime; Sousa, Veronica; Sosic, Izidor; Gobec, Stanislav; Mendoza-Losana, Alfonso; Converse, Paul J.; Mdluli, Khisi; Fotouhi, Nader; Barros-Aguirre, David; Nuermberger, Eric L.
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Contilisant plus Tubastatin A Hybrids: Polyfunctionalized Indole Derivatives as New HDAC Inhibitor-Based Multitarget Small Molecules with In Vitro and In Vivo Activity in Neurodegenerative Diseases
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-09-10
err0
PREAI
errToledano-Pinedo, Mireia; Porro-Perez, Alicia; Schaeker-Huebner, Linda; Romero, Fernando; Dong, Min; Samadi, Abdelouahid; Almendros, Pedro; Iriepa, Isabel; Bautista-Aguilera, Oscar M.; Rodriguez-Fernandez, M. Mercedes; Solana-Manrique, Cristina; Sanchis, Inmaculada; Mora-Morell, Alba; Rodriguez, Ania Canseco; Sanchez-Perez, Ana M.; Knez, Damijan; Gobec, Stanislav; Bellver-Sanchis, Aina; Perez, Belen; Dobrydnev, Alexey V.; Artetxe-Zurutuza, Aizpea; Matheu, Ander; Siwek, Agata; Wolak, Malgorzata; Satala, Grzegorz; Bojarski, Andrzej J.; Doroz-Plonka, Agata; Handzlik, Jadwiga; Godyn, Justyna; Wieckowska, Anna; Paricio, Nuria; Grinan-Ferre, Christian; Hansen, Finn K.; Marco-Contelles, Jose
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Probing Alzheimer's pathology: Exploring the next generation of FDDNP analogues for amyloid β detection
errBIOMEDICINE & PHARMACOTHERAPY
IF7.5
err2024-06-01
err1
errOAAI
errRejc, Luka; Knez, Damijan; Molina-Aguirre, Gabriela; Espargaro, Alba; Kladnik, Jerneja; Meden, Anze; Blinc, Lana; Lozins, Matic; Vuuren, Ross D. Jansen -van; Rogan, Matic; Martek, Bruno Aleksander; Mlakar, Jernej; Dremelj, Ana; Petric, Andrej; Gobec, Stanislav; Sabate, Raimon; Bresjanac, Mara; Pinter, Balazs; Kosmrlj, Janez
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The search for novel proline analogs for viscosity reduction and stabilization of highly concentrated monoclonal antibody solutions
errINTERNATIONAL JOURNAL OF PHARMACEUTICS
IF5.2
err2024-04-01
err4
errOAAI
errPrasnikar, Monika; Proj, Matic; Ziberna, Maja Bjelosevic; Lebar, Blaz; Knez, Benjamin; Krzisnik, Nika; Roskar, Robert; Gobec, Stanislav; Grabnar, Iztok; Zula, Ales; Grabnar, Pegi Ahlin
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研究方向

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