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L

Lúcio H. Freitas-Júnior

University of São Paulo
H指数:34
被引数:5,188

个人简介

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荣誉奖项

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Antibacterial activity of recombinant endolysin LysNOVA-I against growing/non-growing and planktonic/biofilm cultures of Staphylococcus aureus strains

重组裂解酶LysNOVA-I对金黄色葡萄球菌菌株的生长期/非生长期及浮游/生物膜培养物的抗菌活性

Journal of Global Antimicrobial Resistance
IF3.2
2025-11-220
OAAI
Carla Rivero; Melina M.B. Martínez; Nicole G. Picinin; Eduardo G. Martins; Claudio Paolazzi; Alejandra Capozzo; Denise da Silva Oliveira; Johana Becerra; Benedito M. dos Santos; Lucio H.G. de Freitas-Junior; Andrea Balan; Nilton Lincopan; Rita de Cassia Café Ferreira; Luis Carlos de Souza Ferreira; Leticia Verónica Bentancor
Antiviral Action against SARS-CoV-2 of a Synthetic Peptide Based on a Novel Defensin Present in the Transcriptome of the Fire Salamander (Salamandra salamandra)

针对基于火sal (Salamandra salamandra) 转录组中存在的新型防御素的合成肽的SARS-CoV-2的抗病毒作用

PHARMACEUTICS
IF5.5
2024-01-292
OAAI
Barros, Ana Luisa A. N.; Silva, Vladimir C.; Ribeiro-Junior, Atvaldo F.; Cardoso, Miguel G.; Costa, Samuel R.; Moraes, Carolina B.; Barbosa, Cecilia G.; Coleone, Alex P.; Simoes, Rafael P.; Cabral, Wanessa F.; Falcao, Raul M.; Vasconcelos, Andreanne G.; Rocha, Jefferson A.; Arcanjo, Daniel D. R.; Batagin-Neto, Augusto; Borges, Tatiana Karla S.; Goncalves, Joao; Brand, Guilherme D.; Freitas-Junior, Lucio H. G.; Eaton, Peter; Marani, Mariela; Kato, Massuo J.; Placido, Alexandra; Leite, Jose Roberto S. A.
High-Throughput Phenotypic Screening and Machine Learning Methods Enabled the Selection of Broad-Spectrum Low-Toxicity Antitrypanosomatidic Agents
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2023-11-033
OAAI
Linciano, Pasquale; Quotadamo, Antonio; Luciani, Rosaria; Santucci, Matteo; Zorn, Kimberley M.; Foil, Daniel H.; Lane, Thomas R.; da Silva, Anabela Cordeiro; Santarem, Nuno; Moraes, Carolina B.; Freitas-Junior, Lucio; Wittig, Ulrike; Mueller, Wolfgang; Tonelli, Michele; Ferrari, Stefania; Venturelli, Alberto; Gul, Sheraz; Kuzikov, Maria; Ellinger, Bernhard; Reinshagen, Jeanette; Ekins, Sean; Costi, Maria Paola
SARS-CoV-2 Spike protein peptides displayed in the Pyrococcus furiosus RAD system preserve epitopes antigenicity, immunogenicity, and virus-neutralizing activity of antibodies
SCIENTIFIC REPORTS
IF3.9
2023-10-052
OAAI
Cioffi, Victor Bolsanelli; de Castro-Amarante, Maria Fernanda; Lulla, Aleksei; Andreata-Santos, Robert; Cruz, Mario Costa; Ramos Moreno, Ana Carolina; Silva, Mariangela de Oliveira; Peres, Bianca de Miranda; Gondim de Freitas Junior, Lucio Holanda; Moraes, Carolina Borsoi; Durigon, Edison Luiz; Gordon, Nicola Coker; Hyvoenen, Marko; de Souza Ferreira, Luis Carlos; Balan, Andrea
Drug Repurposing in Chagas Disease: Chloroquine Potentiates Benznidazole Activity against Trypanosoma cruzi In Vitro and In Vivo

查加斯病的药物再利用: 氯喹在体外和体内增强了对克氏锥虫的苯并硝唑活性

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
2022-11-1513
OA
Pandey, Ramendra P.; Nascimento, Marilda Savoia; Franco, Caio Haddad; Bortoluci, Karina; Silva, Marcelo Nunes; Zingales, Bianca; Gibaldi, Daniel; Barrios, Leda Castano; Lannes-Vieira, Joseli; Cariste, Leonardo Moro; Vasconcelos, Jose Ronnie; Moraes, Carolina Borsoi; Freitas-Junior, Lucio H.; Kalil, Jorge; Alcantara, Laura; Cunha-Neto, Edecio
Non-Toxic Dimeric Peptides Derived from the Bothropstoxin-I Are Potent SARS-CoV-2 and Papain-like Protease Inhibitors
MOLECULES
IF4.6
2021-08-1223
OAAI
Freire, Marjorie C. L. C.; Noske, Gabriela D.; Bitencourt, Natalia V.; Sanches, Paulo R. S.; Santos-Filho, Norival A.; Gawriljuk, Victor O.; de Souza, Eduardo P.; Nogueira, Victor H. R.; de Godoy, Mariana O.; Nakamura, Aline M.; Fernandes, Rafaela S.; Godoy, Andre S.; Juliano, Maria A.; Peres, Bianca M.; Barbosa, Cecilia G.; Moraes, Carolina B.; Freitas-Junior, Lucio H. G.; Cilli, Eduardo M.; Guido, Rafael V. C.; Oliva, Glaucius
Novel structural CYP51 mutation in Trypanosoma cruzi associated with multidrug resistance to CYP51 inhibitors and reduced infectivity
INTERNATIONAL JOURNAL FOR PARASITOLOGY-DRUGS AND DRUG RESISTANCE
IF3.4
2020-08-019
OAAI
Franco, Caio H.; Warhurst, David C.; Bhattacharyya, Tapan; Au, Ho Y. A.; Le, Hai; Giardini, Miriam A.; Pascoalino, Bruno S.; Torrecilhas, Ana Claudia; Romera, Lavinia M. D.; Madeira, Rafael Pedro; Schenkman, Sergio; Freitas-Junior, Lucio H.; Chatelain, Eric; Miles, Michael A.; Moraes, Carolina B.
Synthesis and structure-activity relationship of nitrile-based cruzain inhibitors incorporating a trifluoroethylamine-based P2 amide replacement
BIOORGANIC & MEDICINAL CHEMISTRY
IF3
2019-11-0118
PREAI
Gomes, Juliana C.; Cianni, Lorenzo; Ribeiro, Jean; Rocho, Fernanda dos Reis; Martins Silva, Samelyn da Costa; Jatai Batista, Pedro Henrique; Moraes, Carolina Borsoi; Franco, Caio Haddad; Freitas-Junior, Lucio H. G.; Kenny, Peter W.; Leitao, Andrei; Burtoloso, Antonio C. B.; de Vita, Daniela; Montanari, Carlos A.
Aryl thiosemicarbazones for the treatment of trypanosomatidic infections

用于治疗锥虫感染的芳基硫代氨基脲

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
2018-02-0132
OAAI
Linciano, Pasquale; Moraes, Carolina B.; Alcantara, Laura M.; Franco, Caio H.; Pascoalino, Bruno; Freitas-Junior, Lucio H.; Macedo, Sara; Santarem, Nuno; Cordeiro-da-Silva, Anabela; Gul, Sheraz; Witt, Gesa; Kuzikov, Maria; Ellinger, Bernhard; Ferrari, Stefania; Luciani, Rosaria; Quotadamo, Antonio; Costantino, Luca; Costi, Maria Paola
Crassiflorone derivatives that inhibit Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase (TbGAPDH) and Trypanosoma cruzi trypanothione reductase (TcTR) and display trypanocidal activity
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
2017-12-0130
OAAI
Uliassi, Elisa; Fiorani, Giulia; Krauth-Siegel, R. Luise; Bergamini, Christian; Fato, Romana; Bianchini, Giulia; Carlos Menendez, J.; Teresa Molina, Maria; Lopez-Montero, Eulogio; Faichi, Federico; Cavalli, Andrea; Gul, Sheraz; Kuzikov, Maria; Ellinger, Bernhard; Witt, Gesa; Moraes, Carolina B.; Freitas-Junior, Lucio H.; Borsari, Chiara; Costi, Maria Paola; Bolognesi, Maria Laura
Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery

利用2-氨基-1，3，4-噻二唑支架抑制布氏锥虫蝶啶还原酶以支持早期药物发现

ACS OMEGA
IF4.3
2017-09-1129
OAAI
Linciano, Pasquale; Dawson, Alice; Poehner, Ina; Costa, David M.; Sa, Monica S.; Cordeiro-da-Silva, Anabela; Luciani, Rosaria; Gul, Sheraz; Witt, Gesa; Ellinger, Bernhard; Kuzikov, Maria; Gribbon, Philip; Reinshagen, Jeanette; Wolf, Markus; Behrens, Birte; Hannaert, Veronique; Michels, Paul A. M.; Nerini, Erika; Pozzi, Cecilia; di Pisa, Flavio; Landi, Giacomo; Santarem, Nuno; Ferrari, Stefania; Saxena, Puneet; Lazzari, Sandra; Cannazza, Giuseppe; Freitas-Junior, Lucio H.; Moraes, Carolina B.; Pascoalino, Bruno S.; Alcantara, Laura M.; Bertolacini, Claudia P.; Fontana, Vanessa; Wittig, Ulrike; Muller, Wolfgang; Wade, Rebecca C.; Hunter, William N.; Mangani, Stefano; Costantino, Luca; Costi, Maria P.

研究方向

暂未获取到该数据
C
Carolina Borsoi Moraes
H 指数:25论文数:90被引数:1,839
C
Caio Haddad Franco
H 指数:16论文数:42被引数:822
M
Maria Paola Costi
H 指数:36论文数:378被引数:4,608
A
Anabela Cordeiro‐da‐Silva
H 指数:46论文数:237被引数:2.3万
E
Eric Chatelain
H 指数:39论文数:105被引数:5,474
M
Maria Kuzikov
H 指数:19论文数:92被引数:1,604
S
Sheraz Gul
H 指数:25论文数:168被引数:2,070
J
Jair L. Siqueira-Neto
H 指数:36论文数:183被引数:3,971
B
Bernhard Ellinger
H 指数:25论文数:114被引数:2,744
L
Laura Maria Alcântara
H 指数:12论文数:24被引数:495