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黄

黄志纾 (Zhi‐Shu Huang)

sun yat sen university

53H指数
302论文数
9.6K被引数
收录论文 162
发表时间
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Discovery of a borylated aza-arene chemotype as a direct HSF1 inhibitor targeting the DNA-binding domain硼化氮杂芳烃化学骨架的发现及其作为靶向DNA结合域的直接HSF1抑制剂的用途
errEuropean Journal of Medicinal Chemistry
IF5.9
err2026-09-29
err0
PREAI
errPan, Xin; Huang, Wei-Hao; Liu, Yao; Zhang, Zhan-Peng; Ye, Jian-Mei; Wu, Yi-Fan; Huang, Zhi-Shu; Wang, Hong-Gen; Huang, Shi-Liang
err分享
err收藏
MitoGPS: A Mitochondrial DNA G-Quadruplex-Targeting Strategy for Tumor-Preferential Type I Photodynamic TherapyMitoGPS：一种靶向线粒体DNA G-四链体的肿瘤选择性I型光动力疗法策略
errAngewandte Chemie-International Edition
IF16.9
err2026-08-28
err0
PREAI
errYu-Hui Guo; Yao-Hui Shi; Pei-Min Huang; Gui-Xue Tang; Shu-Min Xu; Mao-Lin Li; Jia-Hao Yuan; Xiu-Cai Chen; Zhi-Shu Huang; Yi-Yong Yan; Jia-Heng Tan; Jin-Wu Yan; Shuo-Bin Chen
err分享
err收藏
A novel NAMPT activator ameliorates obesity by repressing ACSL1-dependent lipid synthesis一种新型NAMPT激活剂通过抑制ACSL1依赖性脂质合成来改善肥胖
errActa Pharmaceutica Sinica B
IF14.6
err2026-03-25
err0
errOAAI
errZhi Jiang; Yixian Li; Dandan Zhao; Yutao Hu; Lingzhen Xiao; Yuwei Lin; Shumin Xu; Jiachun Luo; Qingjiang Li; Shiliang Huang; Huihao Zhou; Jiaheng Tan; Shuobin Chen; Zhi-Shu Huang
err分享
err收藏
Design and evaluation of an HSP70-targeting PROTAC in synergy with an HSF1 inhibitor for enhanced antitumor activityHSP70靶向PROTAC与HSF1抑制剂协同作用增强抗肿瘤活性的设计与评价
errRSC Med. Chem.
IF3.6
err2025-11-19
err0
PREAI
errWei-Hao Huang; Teng-Yu Mao; Guo-Yao Dai; Jian-Mei Ye; Jia-Bao Li; Shuo-Bin Chen; Jia-Heng Tan; Zhi-Shu Huang; Shi-Liang Huang
err分享
err收藏
Down-Regulation of Oncogene c-myb Specifically by Carbazole Derivative Through Opposing Effects on Different Quadruplex Structures of Gene Promoter for Cancer Treatment通过针对基因启动子不同四链结构的不同拮抗效应，特异性下调癌基因c-myb的咔唑衍生物用于癌症治疗
errInternational Journal of Molecular Sciences 2025, Vol. 26, Page 8299
IF4.9
err2025-08-27
err0
errOAAI
errSiyi Wang; Jihai Liang; Jiahui Zhang; Dongsheng Ji; Zhi-Shu Huang; Ding Li
err分享
err收藏
Development of a Fluorescent Probe for Specific Visualization of Intracellular DNA i-Motif Participating in Key Biological Function开发一种用于特异性可视化参与关键生物学功能的细胞内DNA i-Motif的荧光探针
errACS SENSORS
IF9.1
err2025-04-28
err0
PREAI
errZhang, JH; Liang, JH; Ji, DS; Shu, B; Huang, ZS; Li, D
err分享
err收藏
Recent Progress and Potential of G4 Ligands in Cancer ImmunotherapyG4配体在肿瘤免疫治疗中的研究进展及潜力
errMOLECULES
IF4.6
err2025-04-17
err0
errOAAI
errLin, Jiahui; Gong, Zhu; Lu, Yingyue; Cai, Jiongheng; Zhang, Junjie; Tan, Jiaheng; Huang, Zhishu; Chen, Shuobin
err分享
err收藏
Synergistic anticancer activity of HSP70 and HSF1 inhibitors in colorectal cancer cells: A new strategy for combination therapyHSP70和HSF1抑制剂的协同抗癌活性在结直肠癌细胞中：一种新的联合治疗策略
errBIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
IF4.2
err2025-03-01
err0
PREAI
errXu, Shu-Min; Liu, Xing-Zi; Wang, Lu; Huang, Wei-Hao; Hu, Yu-Tao; Chen, Shuo-Bin; Huang, Zhi-Shu; Huang, Shi-Liang
err分享
err收藏
Selective Up-Regulation of Tumor Suppressor Gene Retinoblastoma by Bisacridine Derivative Through Gene Promoter Quadruplex Structures for Cancer Treatment通过双吖啶衍生物经由基因启动子四链体结构选择性上调视网膜母细胞瘤肿瘤抑制基因，用于癌症治疗
errINTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
IF4.9
err2025-02-07
err0
errOAAI
errLin, Xiaomin; Zhang, Jiahui; Liang, Jihai; Ji, Dongsheng; Huang, Zhi-Shu
err分享
err收藏
Disrupting the protein-protein interaction network of Hsp72 inhibits adipogenic differentiation and lipid synthesis in adipocytes破坏Hsp72的蛋白质-蛋白质相互作用网络抑制脂肪细胞的成脂分化和脂质合成
errCELLULAR SIGNALLING
IF3.7
err2024-12-01
err0
PREAI
errHu, Yu-Tao; Lin, Yu-Wei; Guo, Shi-Yao; Jiang, Zhi; Xu, Shu-Min; Su, Zheng; Zhang, Jin-Ming; Rao, Yong; Chen, Shuo-Bin; Huang, Zhi-Shu
err分享
err收藏
L-aspartate ameliorates diet-induced obesity by increasing adipocyte energy expenditure
errDIABETES OBESITY & METABOLISM
IF5.7
err2024-11-11
err1
PREAI
errGuo, Shi-Yao; Hu, Yu-Tao; Rao, Yong; Jiang, Zhi; Li, Chan; Lin, Yu-Wei; Xu, Shu-min; Zhao, Dan-Dan; Wei, Li-yuan; Huang, Shi-Liang; Li, Qing-Jiang; Tan, Jia-Heng; Chen, Shuo-Bin; Huang, Zhi-Shu
err分享
err收藏
N-Halosuccinimide enables cascade oxidative trifluorination and halogenative cyclization of tryptamine-derived isocyanides
errNATURE COMMUNICATIONS
IF15.7
err2024-10-16
err0
errOAAI
errWu, Jun-Yunzi; Huang, Long-Ling; Fu, Jia-Luo; Li, Jia-Yi; Lin, Shuang; Yang, Shuang; Huang, Zhi-Shu; Wang, Honggen; Li, Qingjiang
err分享
err收藏
Mitochondrial RelA empowers mtDNA G-quadruplex formation for hypoxia adaptation in cancer cells
errCELL CHEMICAL BIOLOGY
IF7.2
err2024-10-01
err1
PREAI
errTang, Gui-Xue; Li, Mao-Lin; Zhou, Cui; Huang, Zhi-Shu; Chen, Shuo-Bin; Chen, Xiu-Cai; Tan, Jia-Heng
err分享
err收藏
Development of Novel N-Acylhydrazone Derivatives with High Anti-obesity Activity and Improved Safety by Exploring the Pharmaceutical Properties of Aldehyde Group
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-07-12
err1
PREAI
errJiang, Zhi; Hu, Yu-Tao; Guo, Shi-Yao; Li, Yi-Xian; Zhao, Dan-Dan; Wei, Li-Yuan; Lin, Yu-Wei; Xu, Shu-Min; Huang, Shi-Liang; Li, Qingjiang; Tan, Jia-Heng; Rao, Yong; Chen, Shuo-Bin; Huang, Zhi-Shu
err分享
err收藏
Discovery of Novel Coumarin-quinolinium Derivatives as Pan-KRAS Translation Inhibitors by Targeting 5′-UTR RNA G-Quadruplexes
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-01-25
err0
PREAI
errLi, Mao-Lin; Dai, Le-Tian; Gao, Zhuo-Yu; Yan, Jia-Tong; Xu, Shu-Min; Tan, Jia-Heng; Huang, Zhi-Shu; Chen, Shuo-Bin; Chen, Xiu-Cai
err分享
err收藏
Discovery of Ingenane Diterpenoids from Euphorbia hylonoma as Antiadipogenic Agents
errJOURNAL OF NATURAL PRODUCTS
IF3.6
err2023-11-17
err0
PREAI
errWu, Shu-Qi; Zhu, Xinying; Yuan, Tao; Yuan, Fang-Yu; Zhou, Shiyou; Huang, Dong; Wang, Ying; Tang, Gui-Hua; Huang, Zhi-Shu; Chen, Xin; Yin, Sheng
err分享
err收藏
Revealing Mitochondrion-Lysosome Dynamic Interactions and pH Variations in Live Cells with a pH-Sensitive Fluorescent Probe
errANALYTICAL CHEMISTRY
IF6.7
err2023-11-02
err16
PREAI
errWang, Jian; Yan, Jia-Tong; Zeng, Shu-Tang; Shao, Wen; Tang, Gui-Xue; Chen, Shuo-Bin; Huang, Zhi-Shu; Tan, Jia-Heng; Chen, Xiu-Cai
err分享
err收藏
Regioselective Electrophilic Addition to Propargylic B(MIDA)s Enabled by β-Boron Effect
errADVANCED SCIENCE
IF14.1
err2023-08-26
err1
errOAAI
errLi, Yin; Chen, Zhi-Hao; Lin, Shuang; Liu, Yuan; Qian, Jiasheng; Li, Qingjiang; Huang, Zhi-Shu; Wang, Honggen
err分享
err收藏
MSN8C: A Promising Candidate for Antitumor Applications as a Novel Catalytic Inhibitor of Topoisomerase II
errMOLECULES
IF4.6
err2023-07-24
err0
errOAAI
errOu, Jie-Bin; Huang, Wei-Hao; Liu, Xing-Zi; Dai, Guo-Yao; Wang, Lu; Huang, Zhi-Shu; Huang, Shi-Liang
err分享
err收藏
Divergent Fluorinations of Vinylcyclopropanes: Ring-Opening 1,5-Hydrofluorination and Ring-Retaining 1,2-Difluorination乙烯基环丙烷的不同氟化: 开环1，5-氢氟化和环保留1，2-二氟化
errCHEMISTRY-AN ASIAN JOURNAL
IF3.3
err2023-07-17
err0
errOAAI
errYang, Shuang; Wu, Jun-Yunzi; Lin, Shuang; Pu, Meicen; Huang, Zhi-Shu; Wang, Honggen; Li, Qingjiang
err分享
err收藏

研究方向

生物有机化学和有机化学
合作学者
合作期刊
张民 封面图
张民 (Min Zhang)
H 指数: 120 · 论文数: 1.8K
王静 封面图
王静 (Jing Wang)
H 指数: 100 · 论文数: 1.5K
王宁 封面图
王宁 (Ning Wang)
H 指数: 99 · 论文数: 1.8K
王斌 封面图
王斌 (Bin Wang)
H 指数: 95 · 论文数: 1.2K
陈
陈潇 (Xiao Dong Chen)
H 指数: 89 · 论文数: 2.0K
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