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D

Dalia Baršytė-Lovejoy

University of Toronto
H指数:53
被引数:1.2万

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PRMT7 restricts CD8+ T cells expansion via the NF-ΚB pathway

PRMT7通过NF-ΚB通路限制CD8+ T细胞扩增

Nature Communications
IF15.7
2026-09-060
OA
Nivine Srour; Kaixiu Luo; David Allard; Yan Xiong; Zhenbao Yu; Theodore Papadopoulos; François Santinon; Cheng-Hsun Hsieh; Anthony Parent; John Stagg; Simon Turcotte; Dalia Barsyte-Lovejoy; Stéphanie Lehoux; Sonia V. del Rincón; Jian Jin; Stéphane Richard
ABHD2 activity is not required for the non-genomic action of progesterone on human sperm

ABHD2活性并非孕酮对人类精子非基因组作用所必需

Human Reproduction
IF6.1
2026-05-290
OA
Madison Edwards; Alexandra Amaral; Eve M Carter; Oliver Arnolds; Karen Vester; Anna Thrun; Edvard Wigren; Evert Homan; Pauline Ribera; Kirsty Bentley; Martin Haraldsson; Nmesoma Theo-Emegano; Peter Loppnau; Magdalena M Szewczyk; Michelle A Cao; Dalia Barsyte-Lovejoy; Nicole Dittmar; Anika Hans; Mandy Weber; Jens Münchow; W Felix Zhu; Louisa Temme; Christoph Brenker; Timo Strünker; Michael Sundström; Matthew H Todd; Aled M Edwards; Ralf Lesche; Opher Gileadi; Claudia Tredup; null
OICR-41103 as a chemical probe for the DCAF1 WD40 domain

OICR-41103 作为 DCAF1 WD40 结构域的化学探针

Communications Biology
IF5.1
2025-07-190
OAAI
Serah W. Kimani; Mahmoud Noureldin; Brian Wilson; Laurent Hoffer; Stuart R. Green; Magdalena M. Szewczyk; Héctor González-Álvarez; Mohammed Mohammed; Manuel Chan; Chiara Krausser; Alice Shi Ming Li; Taraneh Hajian; Sarah Tucker; Dhananjay Joshi; Punit Saraon; Brigitte Thériault; Ji Sup Kim; Vijayaratnam Santhakumar; Peter Loppnau; Yanjun Li; Almagul Seitova; Aiping Dong; Taira Kiyota; Tobias Hammann; Paul Gehrtz; Bhashant Patel; Vaibhavi Rathod; Anand Vala; Bhimsen Rout; Paras Jagodra; Peter J. Brown; Ahmed Aman; Jailall Ramnauth; Gennady Poda; David Uehling; Cheryl H. Arrowsmith; Dalia Barsyte-Lovejoy; Richard Marcellus; Suzanne Ackloo; Ahmed Mamai; Rima Al-awar; Levon Halabelian
PRMT5 promotes full-length HTT expression by repressing multiple proximal intronic polyadenylation sites

PRMT5通过抑制多个近端内含子多聚腺苷酸化位点来促进全长HTT的表达。

NUCLEIC ACIDS RESEARCH
IF13.1
2025-04-300
OA
Yadav, Manisha; AlQazzaz, Mona A.; Ciamponi, Felipe E.; Ho, Jolene C.; Maron, Maxim, I; Sababi, Aiden M.; MacLeod, Graham; Ahmadi, Moloud; Bullivant, Garrett; Tano, Vincent; Langley, Sarah R.; Sanchez-Osuna, Maria; Sachamitr, Patty; Kushida, Michelle; Bardile, Costanza Ferrari; Pouladi, Mahmoud A.; Kurtz, Rebecca; Richards, Laura; Pugh, Trevor; Tyers, Mike; Angers, Stephane; Dirks, Peter B.; Bader, Gary D.; Truant, Ray; Massirer, Katlin B.; Barsyte-Lovejoy, Dalia; Shechter, David; Harding, Rachel J.; Arrowsmith, Cheryl H.; Prinos, Panagiotis
Recruitment of FBXO22 for targeted degradation of NSD2

招募FBXO22靶向降解NSD2

NATURE CHEMICAL BIOLOGY
IF13.7
2024-07-047
PRE
Nie, David Y.; Tabor, John R.; Li, Jianping; Kutera, Maria; St-Germain, Jonathan; Hanley, Ronan P.; Wolf, Esther; Paulakonis, Ethan; Kenney, Tristan M. G.; Duan, Shili; Shrestha, Suman; Owens, Dominic D. G.; Maitland, Matthew E. R.; Pon, Ailing; Szewczyk, Magdalena; Lamberto, Anthony Joseph; Menes, Michael; Li, Fengling; Penn, Linda Z.; Barsyte-Lovejoy, Dalia; Brown, Nicholas G.; Barsotti, Anthony M.; Stamford, Andrew W.; Collins, Jon L.; Wilson, Derek J.; Raught, Brian; Licht, Jonathan D.; James, Lindsey I.; Arrowsmith, Cheryl H.
A chemical probe to modulate human GID4 Pro/N-degron interactions
NATURE CHEMICAL BIOLOGY
IF13.7
2024-05-214
PRE
Owens, Dominic D. G.; Maitland, Matthew E. R.; Yazdi, Aliakbar Khalili; Song, Xiaosheng; Reber, Viviane; Schwalm, Martin P.; Machado, Raquel A. C.; Bauer, Nicolas; Wang, Xu; Szewczyk, Magdalena M.; Dong, Cheng; Dong, Aiping; Loppnau, Peter; Calabrese, Matthew F.; Dowling, Matthew S.; Lee, Jisun; Montgomery, Justin I.; O'Connell, Thomas N.; Subramanyam, Chakrapani; Wang, Feng; Adamson, Ella C.; Schapira, Matthieu; Gstaiger, Matthias; Knapp, Stefan; Vedadi, Masoud; Min, Jinrong; Lajoie, Gilles A.; Barsyte-Lovejoy, Dalia; Owen, Dafydd R.; Schild-Poulter, Caroline; Arrowsmith, Cheryl H.
Chemical tools for the Gid4 subunit of the human E3 ligase C-terminal to LisH (CTLH) degradation complex
RSC MEDICINAL CHEMISTRY
IF3.6
2024-01-013
OA
Yazdi, Aliakbar Khalili; Perveen, Sumera; Dong, Cheng; Song, Xiaosheng; Dong, Aiping; Szewczyk, Magdalena M.; Calabrese, Matthew F.; Casimiro-Garcia, Agustin; Chakrapani, Subramanyam; Dowling, Matthew S.; Ficici, Emel; Lee, Jisun; Montgomery, Justin I.; O'Connell, Thomas N.; Skrzypek, Grzegorz J.; Tran, Tuan P.; Troutman, Matthew D.; Wang, Feng; Young, Jennifer A.; Min, Jinrong; Barsyte-Lovejoy, Dalia; Brown, Peter J.; Santhakumar, Vijayaratnam; Arrowsmith, Cheryl H.; Vedadi, Masoud; Owen, Dafydd R.
Development of HC-258, a Covalent Acrylamide TEAD Inhibitor That Reduces Gene Expression and Cell Migration

HC-258的开发，一种共价丙烯酰胺TEAD抑制剂，可减少基因表达和细胞迁移

ACS MEDICINAL CHEMISTRY LETTERS
IF4
2023-11-306
PRE
Fnaiche, Ahmed; Chan, Hwai-Chien; Paquin, Alexis; Suarez, Narjara Gonzalez; Vu, Victoria; Li, Fengling; Allali-Hassani, Abdellah; Cao, Michelle Ada; Szewczyk, Magdalena M.; Bolotokova, Albina; Allemand, Frederic; Gelin, Muriel; Barsyte-Lovejoy, Dalia; Santhakumar, Vijayaratnam; Vedadi, Masoud; Guichou, Jean-Francois; Annabi, Borhane; Gagnon, Alexandre
Discovery and Characterization of a Chemical Probe Targeting the Zinc-Finger Ubiquitin-Binding Domain of HDAC6
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2023-07-273
OAAI
Harding, Rachel J.; Franzoni, Ivan; Mann, Mandeep K.; Szewczyk, Magdalena M.; Mirabi, Bijan; de Freitas, Renato Ferreira; Owens, Dominic D. G.; Ackloo, Suzanne; Scheremetjew, Alexej; Juarez-Ornelas, Kevin A.; Sanichar, Randy; Baker, Rachel J.; Dank, Christian; Brown, Peter J.; Barsyte-Lovejoy, Dalia; Santhakumar, Vijayaratnam; Schapira, Matthieu; Lautens, Mark; Arrowsmith, Cheryl H.
Discovery of a Potent and Selective Targeted NSD2 Degrader for the Reduction of H3K36me2

发现一种有效且选择性的靶向NSD2降解剂，用于还原H3K36me2

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
2023-03-2825
PRE
Hanley, Ronan P.; Nie, David Y.; Tabor, John R.; Li, Fengling; Sobh, Amin; Xu, Chenxi; Barker, Natalie K.; Dilworth, David; Hajian, Taraneh; Gibson, Elisa; Szewczyk, Magdalena M.; Brown, Peter J.; Barsyte-Lovejoy, Dalia; Herring, Laura E.; Wang, Gang Greg; Licht, Jonathan D.; Vedadi, Masoud; Arrowsmith, Cheryl H.; James, Lindsey I.
Discovery of Nanomolar DCAF1 Small Molecule Ligands
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2023-03-2220
OAAI
Li, Alice Shi Ming; Kimani, Serah; Wilson, Brian; Noureldin, Mahmoud; Gonzalez-Alvarez, Hector; Mamai, Ahmed; Hoffer, Laurent; Guilinger, John P.; Zhang, Ying; von Rechenberg, Moritz; Disch, Jeremy S.; Mulhern, Christopher J.; Slakman, Belinda L.; Cuozzo, John W.; Dong, Aiping; Poda, Gennady; Mohammed, Mohammed; Saraon, Punit; Mittal, Manish; Modh, Prati k; Rathod, Vaibhavi; Patel, Bhashant; Ackloo, Suzanne; Santhakumar, Vijayaratnam; Szewczyk, Magdalena M.; Barsyte-Lovejoy, Dalia; Arrowsmith, Cheryl H.; Marcellus, Richard; Guie, Marie-Aude; Keefe, Anthony D.; Brown, Peter J.; Halabelian, Levon; Al-awar, Rima; Vedadi, Masoud
Reference compounds for characterizing cellular injury in high-content cellular morphology assays
NATURE COMMUNICATIONS
IF15.7
2023-03-1310
OAAI
Dahlin, Jayme L.; Hua, Bruce K.; Zucconi, Beth E.; Nelson, Shawn D.; Singh, Shantanu; Carpenter, Anne E.; Shrimp, Jonathan H.; Lima-Fernandes, Evelyne; Wawer, Mathias J.; Chung, Lawrence P. W.; Agrawal, Ayushi; O'Reilly, Mary; Barsyte-Lovejoy, Dalia; Szewczyk, Magdalena; Li, Fengling; Lak, Parnian; Cuellar, Matthew; Cole, Philip A.; Meier, Jordan L.; Thomas, Tim; Baell, Jonathan B.; Brown, Peter J.; Walters, Michael A.; Clemons, Paul A.; Schreiber, Stuart L.; Wagner, Bridget K.
Discovery and Characterization of BAY-805, a Potent and Selective Inhibitor of Ubiquitin-Specific Protease USP21
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2023-02-207
OAAI
Goericke, Fabian; Vu, Victoria; Smith, Leanna; Scheib, Ulrike; Boehm, Raphael; Akkilic, Namik; Wohlfahrt, Gerd; Weiske, Joerg; Boemer, Ulf; Brzezinka, Krzysztof; Lindner, Niels; Lienau, Philip; Gradl, Stefan; Beck, Hartmut; Brown, Peter J.; Santhakumar, Vijayaratnam; Vedadi, Masoud; Barsyte-Lovejoy, Dalia; Arrowsmith, Cheryl H.; Schmees, Norbert; Petersen, Kirstin

研究方向

暂未获取到该数据
C
C.H. Arrowsmith
H 指数:112论文数:3,098被引数:4.2万
M
Masoud Vedadi
H 指数:70论文数:400被引数:1.8万
P
Peter J. Brown
H 指数:66论文数:347被引数:1.8万
F
Fengling Li
H 指数:56论文数:258被引数:1.0万
M
Magdalena M. Szewczyk
H 指数:33论文数:110被引数:3,843
M
Matthieu Schapira
H 指数:60论文数:414被引数:1.7万
J
Jian Jin
H 指数:74论文数:494被引数:2.1万
A
Aiping Dong
H 指数:49论文数:218被引数:7,741
M
Mohammad S. Eram
H 指数:23论文数:43被引数:2,051
A
Abdellah Allali‐Hassani
H 指数:44论文数:160被引数:7,330