Rasmus Jansson‐Löfmark - Publications, H-index & Citations

Rasmus Jansson‐Löfmark

astrazeneca

30H指数

105论文数

3.2K被引数

收录论文 46

发表时间

Application of Virtual Twin PBPK Models in Individuals with Obesity via CYP3A4 Phenotyping Using Endogenous Biomarker Data 利用内源性生物标志物数据进行CYP3A4表型分型，在肥胖个体中应用虚拟孪生PBPK模型

CLINICAL PHARMACOLOGY & THERAPEUTICS

IF5.5

2026-06-18

OAAI

Nihan Izat; Haribhau Kangne; Rasmus Jansson-Löfmark; Jens K. Hertel; Amin Rostami-Hodjegan; Ida Robertsen; Aleksandra Galetin

Systemic Pharmacokinetic Principles of Therapeutic Peptides 治疗性肽的系统药代动力学原理

Clinical Pharmacokinetics

IF4

2026-02-09

PREAI

Pär Nordell; Rasmus Jansson-Löfmark; Peter Gennemark

Virtual Twin-PBPK Modelling: A Step Toward Precision Dosing in Patients with Obesity 虚拟孪生-PBPK建模：实现肥胖患者精准给药的一步

The AAPS Journal

IF0

2026-01-08

OAAI

Haribhau Kangne; Nihan Izat; Gong Chen; Kayode Ogungbenro; Rasmus Jansson-Löfmark; Jens K. Hertel; Ida Robertsen; Aleksandra Galetin

Pharmacokinetics of Racemic Eflornithine in Human Plasma and Cerebrospinal Fluid: Clinical Perspectives for L-eflornithine Against Human African Trypanosomiasis (L)-eftornithine在人体血浆和脑脊液中的药代动力学：L-eflornithine治疗人非洲锥虫病的临床视角

aaps journal

IF0

2025-09-04

OAAI

Mikael Boberg; Kesara Na-Bangchang; Michael Ashton; Rasmus Jansson-Löfmark

Translational PK/PD: a retrospective analysis of performance and impact from a drug portfolio 转化药代动力学/药效学：基于药物组合的绩效与影响的回顾性分析

Drug Discovery Today

IF7.5

2025-06-23

OAAI

Rasmus Jansson-Löfmark; Markus Fridén; Lassina Badolo; Christine Ahlström; Ian Gurrell; Menelas N. Pangalos; Rhys DO Jones

A multi-omics microbiome signature is associated with the benefits of gastric bypass surgery and is differentiated from diet induced weight loss through 2 years of follow-up 多组学微生物组特征与胃旁路手术的益处相关，且在为期2年的随访中与饮食诱导的体重减轻存在差异。

Mucosal Immunology

IF7.6

2025-04-11

OAAI

Vancheswaran Gopalakrishnan; Chanchal Kumar; Ida Robertsen; Christopher Morehouse; Ben Sparklin; Shameer Khader; Ian Henry; Line Kristin Johnson; Jens K. Hertel; Hege Christensen; Rune Sandbu; Peter J. Greasley; Bret R. Sellman; Anders Åsberg; Shalini Andersson; Rasmus Jansson Löfmark; Jøran Hjelmesæth; Cecilia Karlsson; Taylor S. Cohen

SGLT2 inhibition improves coronary flow velocity reserve and contractility: role of glucagon signaling

CARDIOVASCULAR DIABETOLOGY

IF10.6

2024-11-15

OAAI

Gopel, Sven O.; Adingupu, Damilola; Wang, Jue; Semenova, Elizaveta; Behrendt, Margareta; Jansson-Lofmark, Rasmus; Ahlstrom, Christine; Jonsson-Rylander, Ann-Cathrine; Gopaul, V. Sashi; Esterline, Russell; Gan, Li-Ming; Xiao, Rui-Ping

Establishing a Relationship between In Vitro Potency in Cell-Based Assays and Clinical Efficacious Concentrations for Approved GLP-1 Receptor Agonists

PHARMACEUTICS

IF5.5

2024-10-08

OAAI

Boianelli, Alessandro; Nordell, Par; Earl, Joseph; Naylor, Jacqueline; Hornigold, David; Lofmark, Rasmus Jansson; Sundqvist, Monika

Gastric Bypass vs Diet and Cardiovascular Risk Factors A Nonrandomized Controlled Trial

JAMA SURGERY

IF14.9

2024-09-01

OAAI

Karlsson, Cecilia; Johnson, Line Kristin; Greasley, Peter J.; Retterstol, Kjetil; Hedberg, Jonatan; Hall, Martin; Hawker, Noele; Robertsen, Ida; Havsol, Jesper; Hertel, Jens Kristoffer; Sandbu, Rune; Skovlund, Eva; Olsen, Thomas; Christensen, Hege; Jansson-Lofmark, Rasmus; Andersson, Shalini; Asberg, Anders; Hjelmesaeth, Joran

Normoglycemia and physiological cortisone level maintain glucose homeostasis in a pancreas-liver microphysiological system

COMMUNICATIONS BIOLOGY

IF5.1

2024-07-18

OAAI

Rigal, Sophie; Casas, Belen; Kanebratt, Kajsa P.; Huldt, Charlotte Wennberg; Magnusson, Lisa U.; Mullers, Erik; Karlsson, Fredrik; Clausen, Maryam; Hansson, Sara F.; Leonard, Louise; Cairns, Jonathan; Lofmark, Rasmus Jansson; Ammala, Carina; Marx, Uwe; Gennemark, Peter; Cedersund, Gunnar; Andersson, Tommy B.; Vilen, Liisa K.

Oral Drug Dosing After Gastric Bypass and Diet-Induced Weight Loss: Simpler Than We Think? Lessons Learned From the COCKTAIL Study

CLINICAL PHARMACOLOGY & THERAPEUTICS

IF5.5

2024-05-21

OAAI

Kvitne, Kine Eide; Hjelmesaeth, Joran; Hovd, Markus; Sandbu, Rune; Johnson, Line Kristin; Andersson, Shalini; Karlsson, Cecilia; Christensen, Hege; Jansson-Lofmark, Rasmus; Asberg, Anders; Robertsen, Ida

A case-study of model-informed drug development of a novel PCSK9 anti sense oligonucleotide. Part 1: First time in man to phase II

CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY

IF3

2022-10-01

OAAI

Knochel, Jane; Nilsson, Catarina; Carlsson, Bjorn; Wernevik, Linda; Hofherr, Alexis; Gennemark, Peter; Jansson-Lofmark, Rasmus; Isaksson, Rikard; Ryden-Bergsten, Tina; Hamren, Bengt; Rekic, Dinko

Impact of type 2 diabetes on in vivo activities and protein expressions of cytochrome P450 in patients with obesity

CTS-CLINICAL AND TRANSLATIONAL SCIENCE

IF2.8

2022-09-08

OAAI

Kvitne, Kine Eide; Asberg, Anders; Johnson, Line K.; Wegler, Christine; Hertel, Jens K.; Artursson, Per; Karlsson, Cecilia; Andersson, Shalini; Sandbu, Rune; Skovlund, Eva; Christensen, Hege; Jansson-Lofmark, Rasmus; Hjelmesaeth, Joran; Robertsen, Ida

Short- and long-term effects of body weight, calorie restriction and gastric bypass on CYP1A2, CYP2C19 and CYP2C9 activity

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

IF3

2022-04-25

OAAI

Kvitne, Kine Eide; Krogstad, Veronica; Wegler, Christine; Johnson, Line Kristin; Kringen, Marianne K.; Hovd, Markus Herberg; Hertel, Jens K.; Heijer, Maria; Sandbu, Rune; Skovlund, Eva; Artursson, Per; Karlsson, Cecilia; Andersson, Shalini; Andersson, Tommy B.; Hjelmesaeth, Joran; Asberg, Anders; Jansson-Lofmark, Rasmus; Christensen, Hege; Robertsen, Ida

Population Pharmacodynamic Modeling of Eflornithine-Based Treatments Against Late-Stage Gambiense Human African Trypanosomiasis and Efficacy Predictions of L-eflornithine-Based Therapy

AAPS JOURNAL

IF3.7

2022-03-25

OAAI

Amilon, Carl; Boberg, Mikael; Tarning, Joel; Abelo, Angela; Ashton, Michael; Jansson-Lofmark, Rasmus

Drug Disposition Protein Quantification in Matched Human Jejunum and Liver From Donors With Obesity

CLINICAL PHARMACOLOGY & THERAPEUTICS

IF5.5

2022-03-06

OAAI

Wegler, Christine; Wisniewski, Jacek R.; Robertsen, Ida; Christensen, Hege; Hertel, Jens Kristoffer; Hjelmesaeth, Joran; Jansson-Lofmark, Rasmus; Asberg, Anders; Andersson, Tommy B.; Artursson, Per

Short- and long-term effects of body weight loss following calorie restriction and gastric bypass on CYP3A-activity - a non-randomized three-armed controlled trial

CTS-CLINICAL AND TRANSLATIONAL SCIENCE

IF2.8

2021-08-26

OAAI

Kvitne, Kine Eide; Robertsen, Ida; Skovlund, Eva; Christensen, Hege; Krogstad, Veronica; Wegler, Christine; Angeles, Philip Carlo; Wollmann, Birgit Malene; Hole, Kristine; Johnson, Line Kristin; Sandbu, Rune; Artursson, Per; Karlsson, Cecilia; Andersson, Shalini; Andersson, Tommy B.; Hjelmesaeth, Joran; Jansson-Lofmark, Rasmus; Asberg, Anders

Enantiospecific antitrypanosomal in vitro activity of eflornithine

PLOS NEGLECTED TROPICAL DISEASES

IF3.4

2021-07-12

OAAI

Boberg, Mikael; Cal, Monica; Kaiser, Marcel; Jansson-Lofmark, Rasmus; Maser, Pascal; Ashton, Michael

Comparisons of basic target-mediated drug disposition (TMDD) and ligand facilitated target removal (LFTR)

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

IF4.7

2021-07-01

OAAI

Peletier, Lambertus A.; Jansson-Lofmark, Rasmus; Gabrielsson, Johan

Effects of mineral oil administration on the pharmacokinetics, metabolism and pharmacodynamics of atorvastatin and pravastatin in mice and dogs

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

IF4.7

2021-06-01

OAAI

Gopaul, V. Sashi; Pieterman, Elsbet J.; Princen, Hans M. G.; Bergenholm, Linnea; Lundborg, Eva; Cavallin, Anders; Johansson, Magnus J.; Hawthorne, Glen; Bjorkbom, Anders; Hammarberg, Maria; Li, XueQing; Jarke, Annica; Bright, Jonathan; Svensson, Lena; Jansson-Lofmark, Rasmus; Abrahamsson, Bertil; Agrawal, Rahul; Hurt-Camejo, Eva

研究方向