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D

David F. Vincent

Université Claude Bernard Lyon 1
H指数:23
被引数:2,205

个人简介

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Epithelial TGFβ engages growth-factor signalling to circumvent apoptosis and drive intestinal tumourigenesis with aggressive features

上皮tgf β 参与生长因子信号传导以避免细胞凋亡并以侵袭性特征驱动肠道肿瘤发生

NATURE COMMUNICATIONS
IF15.7
2022-12-074
OAAI
Flanagan, Dustin J.; Amirkhah, Raheleh; Vincent, David F.; Gunduz, Nuray; Gentaz, Pauline; Cammareri, Patrizia; McCooey, Aoife J.; McCorry, Amy M. B.; Fisher, Natalie C.; Davis, Hayley L.; Ridgway, Rachel A.; Lohuis, Jeroen; Leach, Joshua D. G.; Jackstadt, Rene; Gilroy, Kathryn; Mariella, Elisa; Nixon, Colin; Clark, William; Hedley, Ann; Markert, Elke K.; Strathdee, Douglas; Bartholin, Laurent; Redmond, Keara L.; Kerr, Emma M.; Longley, Daniel B.; Ginty, Fiona; Cho, Sanghee; Coleman, Helen G.; Loughrey, Maurice B.; Bardelli, Alberto; Maughan, Timothy S.; Campbell, Andrew D.; Lawler, Mark; Leedham, Simon J.; Barry, Simon T.; Inman, Gareth J.; van Rheenen, Jacco; Dunne, Philip D.; Sansom, Owen J.
Aberrant Expression and Subcellular Localization of ECT2 Drives Colorectal Cancer Progression and Growth

ECT2的异常表达和亚细胞定位驱动结直肠癌的进展和生长

CANCER RESEARCH
IF16.6
2022-01-0423
OA
Cook, Danielle R.; Kang, Melissa; Martin, Timothy D.; Galanko, Joseph A.; Loeza, Gabriela H.; Trembath, Dimitri G.; Justilien, Verline; Pickering, Karen A.; Vincent, David F.; Jarosch, Armin; Jurmeister, Philipp; Waters, Andrew M.; Hibshman, Priya S.; Campbell, Andrew D.; Ford, Catriona A.; Keku, Temitope O.; Yeh, Jen Jen; Lee, Michael S.; Cox, Adrienne D.; Fields, Alan P.; Sandler, Robert S.; Sansom, Owen J.; Sers, Christine; Schaefer, Antje; Der, Channing J.
Oncogenic BRAF, unrestrained by TGFβ-receptor signalling, drives right-sided colonic tumorigenesis
NATURE COMMUNICATIONS
IF15.7
2021-06-0842
OAAI
Leach, Joshua D. G.; Vlahov, Nikola; Tsantoulis, Petros; Ridgway, Rachel A.; Flanagan, Dustin J.; Gilroy, Kathryn; Sphyris, Nathalie; Vazquez, Ester G.; Vincent, David F.; Faller, William J.; Hodder, Michael C.; Raven, Alexander; Fey, Sigrid; Najumudeen, Arafath K.; Strathdee, Douglas; Nixon, Colin; Hughes, Mark; Clark, William; Shaw, Robin; van Hooff, Sander R.; Huels, David J.; Medema, Jan Paul; Barry, Simon T.; Frame, Margaret C.; Unciti-Broceta, Asier; Leedham, Simon J.; Inman, Gareth J.; Jackstadt, Rene; Thompson, Barry J.; Campbell, Andrew D.; Tejpar, Sabine; Sansom, Owen J.
A RAC-GEF network critical for early intestinal tumourigenesis
NATURE COMMUNICATIONS
IF15.7
2021-01-0411
OAAI
Pickering, K. A.; Gilroy, K.; Cassidy, J. W.; Fey, S. K.; Najumudeen, A. K.; Zeiger, L. B.; Vincent, D. F.; Gay, D. M.; Johansson, J.; Fordham, R. P.; Miller, B.; Clark, W.; Hedley, A.; Unal, E. B.; Kiel, C.; McGhee, E.; Machesky, L. M.; Nixon, C.; Johnsson, A. E.; Bain, M.; Strathdee, D.; van Hoof, S. R.; Medema, J. P.; Anderson, K., I; Brachmann, S. M.; Stucke, V. M.; Malliri, A.; Drysdale, M.; Turner, M.; Serrano, L.; Myant, K.; Campbell, A. D.; Sansom, O. J.
TGFβ inhibition restores a regenerative response in acute liver injury by suppressing paracrine senescence

Tgf β 抑制通过抑制旁分泌衰老恢复急性肝损伤的再生反应

SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2018-08-15188
OAAI
Bird, Thomas G.; Mueller, Miryam; Boulter, Luke; Vincent, David F.; Ridgway, Rachel A.; Lopez-Guadamillas, Elena; Lu, Wei-Yu; Jamieson, Thomas; Govaere, Olivier; Campbell, Andrew D.; Ferreira-Gonzalez, Sofia; Cole, Alicia M.; Hay, Trevor; Simpson, Kenneth J.; Clark, William; Hedley, Ann; Clarke, Mairi; Gentaz, Pauline; Nixon, Colin; Bryce, Steven; Kiourtis, Christos; Sprangers, Joep; Nibbs, Robert J. B.; Van Rooijen, Nico; Bartholin, Laurent; McGreal, Steven R.; Apte, Udayan; Barry, Simon T.; Iredale, John P.; Clarke, Alan R.; Serrano, Manuel; Roskams, Tania A.; Sansom, Owen J.; Forbes, Stuart J.
Acinar-to-Ductal Metaplasia Induced by Transforming Growth Factor Beta Facilitates KRASG12D-driven Pancreatic Tumorigenesis
CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY
IF7.4
2017-09-0154
OAAI
Chuvin, Nicolas; Vincent, David F.; Pommier, Roxane M.; Alcaraz, Lindsay B.; Gout, Johann; Caligaris, Cassandre; Yacoub, Karam; Cardot, Victoire; Roger, Elodie; Kaniewski, Bastien; Martel, Sylvie; Cintas, Celia; Goddard-Leon, Sophie; Colombe, Amelie; Valantin, Julie; Gadot, Nicolas; Servoz, Emilie; Morton, Jennifer; Goddard, Isabelle; Couvelard, Anne; Rebours, Vinciane; Guillermet, Julie; Sansom, Owen J.; Treilleux, Isabelle; Valcourt, Ulrich; Sentis, Stephanie; Dubus, Pierre; Bartholin, Laurent
Inactivation of TGFβ receptors in stem cells drives cutaneous squamous cell carcinoma
NATURE COMMUNICATIONS
IF15.7
2016-08-2587
OAAI
Cammareri, Patrizia; Rose, Aidan M.; Vincent, David F.; Wang, Jun; Nagano, Ai; Libertini, Silvana; Ridgway, Rachel A.; Athineos, Dimitris; Coates, Philip J.; McHugh, Angela; Pourreyron, Celine; Dayal, Jasbani H. S.; Larsson, Jonas; Weidlich, Simone; Spender, Lindsay C.; Sapkota, Gopal P.; Purdie, Karin J.; Proby, Charlotte M.; Harwood, Catherine A.; Leigh, Irene M.; Clevers, Hans; Barker, Nick; Karlsson, Stefan; Pritchard, Catrin; Marais, Richard; Chelala, Claude; South, Andrew P.; Sansom, Owen J.; Inman, Gareth J.
Frequent loss of function mutations in TGFβR1 and TGFβR2 identify hair follicle bulge stem cells as the cell of origin for cutaneous squamous cell carcinoma
CANCER RESEARCH
IF16.6
2015-08-010
PRE
Cammareri, Patrizia; Rose, Aidan M.; Vincent, David F.; Libertini, Silvana; Ridgway, Rachel A.; Athineos, Dimitris; Coates, Philip; McHugh, Angela; Pourreyron, Celine; Larsson, Jonas; Spender, Lindsay C.; Sapkota, Gopal; Purdie, Karin; Proby, Charlotte; Harwood, Catherine A.; Leigh, Irene M.; Clevers, Hans; Barker, Nicholas; Karlsson, Stefan; Pritchard, Catrin; Marais, Richard; South, Andrew P.; Sansom, Owen J.; Inman, Gareth J.

研究方向

暂未获取到该数据
L
Laurent Bartholin
H 指数:38论文数:97被引数:5,534
O
Owen J. Sansom
H 指数:113论文数:1,190被引数:5.1万
A
Andrew D. Campbell
H 指数:39论文数:325被引数:6,405
R
Rachel A. Ridgway
H 指数:47论文数:254被引数:1.1万
S
Sylvie Martel
H 指数:24论文数:79被引数:1,538
C
Colin Nixon
H 指数:56论文数:400被引数:1.2万
P
Patrizia Cammareri
H 指数:24论文数:87被引数:4,549
G
Gareth J. Inman
H 指数:39论文数:129被引数:8,789
U
Ulrich Valcourt
H 指数:28论文数:61被引数:3,598
R
Roxane M. Pommier
H 指数:18论文数:152被引数:1,231