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M

Mikael Marttinen

European Molecular Biology Laboratory
H指数:19
被引数:1,397

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荣誉奖项

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Functional phenotyping of genomic variants using joint multiomic single-cell DNA–RNA sequencing

利用联合多组学单细胞DNA–RNA测序对基因组变体进行功能表型分析。Nat. Methods 22, 1–10

Nature Methods
IF32.1
2025-09-010
OAAI
Dominik Lindenhofer; Julia R. Bauman; John A. Hawkins; Donnacha Fitzgerald; Umut Yildiz; Haeyeon Jung; Anastasiia Korosteleva; Mikael Marttinen; Moritz Kueblbeck; Judith B. Zaugg; Kyung-Min Noh; Sascha Dietrich; Wolfgang Huber; Oliver Stegle; Lars M. Steinmetz
Single-cell ultra-high-throughput multiplexed chromatin and RNA profiling reveals gene regulatory dynamics

单细胞超高 throughput 多重染色质和 RNA 定制分析揭示了基因调控动态

NATURE METHODS
IF32.1
2025-05-261
OA
Lobato-Moreno, Sara; Yildiz, Umut; Claringbould, Annique; Servaas, Nila H.; Vlachou, Evi P.; Arnold, Christian; Bauersachs, Hanke Gwendolyn; Campos-Fornes, Victor; Kim, Minyoung; Berest, Ivan; Prummel, Karin D.; Noh, Kyung-Min; Marttinen, Mikael; Zaugg, Judith B.
A small TAT-TrkB peptide prevents BDNF receptor cleavage and restores synaptic physiology in Alzheimer's disease (Vol 32, pg 3372, 2024)

一种小分子TAT-TrkB多肽可防止BDNF受体裂解，并恢复阿尔茨海默病中的突触生理学（卷32，页3372，2024）

MOLECULAR THERAPY
IF12
2025-01-011
OAAI
Fonseca-Gomes, Joao; Costa-Coelho, Tiago; Ferreira-Manso, Mafalda; Inteiro-Oliveira, Sara; Vaz, Sandra H.; Aleman-Serrano, Nuno; Atalaia-Barbacena, Henrique; Ribeiro-Rodrigues, Leonor; Ramalho, Rita M.; Pinto, Rui; Miranda, Hugo Vicente; Tanqueiro, Sara R.; de Almeida-Borlido, Carolina; Ramalho, Maria Joao; Miranda-Lourenco, Catarina; Belo, Rita F.; Ferreira, Catarina B.; Neves, Vera; Rombo, Diogo M.; Viais, Ricardo; Umemori, Juzoh; Martins, Ivo C.; Jeronimo-Santos, Andre; Caetano, Antonio; Manso, Nuno; Makinen, Petra; Marttinen, Mikael; Takalo, Mari; Bremang, Michael; Pike, Ian; Haapasalo, Annakaisa; Loureiro, Joana A.; Pereira, Maria Carmo; Santos, Nuno C.; Outeiro, Tiago F.; Castanho, Miguel A. R. B.; Fernandes, Adelaide; Hiltunen, Mikko; Duarte, Carlos B.; Castren, Eero; de Mendonca, Alexandre; Sebastiao, Ana M.; Rodrigues, Tiago M.; Diogenes, Maria Jose
Single cell and spatial transcriptomics highlight the interaction of club-like cells with immunosuppressive myeloid cells in prostate cancer
NATURE COMMUNICATIONS
IF15.7
2024-11-160
OAAI
Kiviaho, Antti; Eerola, Sini K.; Kallio, Heini M. L.; Andersen, Maria K.; Hoikka, Miina; Tiihonen, Aliisa M.; Salonen, Iida; Spotbeen, Xander; Giesen, Alexander; Parker, Charles T. A.; Taavitsainen, Sinja; Hantula, Olli; Marttinen, Mikael; Hermelo, Ismail; Ismail, Mazlina; Midtbust, Elise; Wess, Maximilian; Devlies, Wout; Sharma, Abhibhav; Krossa, Sebastian; Hakkinen, Tomi; Afyounian, Ebrahim; Vandereyken, Katy; Kint, Sam; Kesseli, Juha; Tolonen, Teemu; Tammela, Teuvo L. J.; Viset, Trond; Storkersen, Oystein; Giskeodegard, Guro F.; Rye, Morten B.; Murtola, Teemu; Erickson, Andrew; Latonen, Leena; Bova, G. Steven; Mills, Ian G.; Joniau, Steven; Swinnen, Johannes V.; Voet, Thierry; Mirtti, Tuomas; Attard, Gerhardt; Claessens, Frank; Visakorpi, Tapio; Rautajoki, Kirsi J.; Tessem, May-Britt; Urbanucci, Alfonso; Nykter, Matti
Protective Alzheimer's disease-associated APP A673T variant predominantly decreases sAPPβ levels in cerebrospinal fluid and 2D/3D cell culture models
NEUROBIOLOGY OF DISEASE
IF5.6
2023-06-017
OAAI
Wittrahm, Rebekka; Takalo, Mari; Kuulasmaa, Teemu; Maekinen, Petra M.; Maekinen, Petri; Koncarevic, Sasa; Fartzdinov, Vadim; Selzer, Stefan; Kokkola, Tarja; Antikainen, Leila; Martiskainen, Henna; Kemppainen, Susanna; Marttinen, Mikael; Jeskanen, Heli; Rostalski, Hannah; Rahunen, Eija; Kivipelto, Miia; Ngandu, Tiia; Natunen, Teemu; Lambert, Jean-Charles; Tanzi, Rudolph E.; Kim, Doo Yeon; Rauramaa, Tuomas; Herukka, Sanna-Kaisa; Soininen, Hilkka; Laakso, Markku; Pike, Ian; Leinonen, Ville; Haapasalo, Annakaisa; Hiltunen, Mikko
S327 phosphorylation of the presynaptic protein SEPTIN5 increases in the early stages of neurofibrillary pathology and alters the functionality of SEPTIN5
NEUROBIOLOGY OF DISEASE
IF5.6
2022-02-0110
OAAI
Ferreira, Catarina B.; Marttinen, Mikael; Coelho, Joana E.; Paldanius, Kaisa M. A.; Takalo, Mari; Makinen, Petra; Leppanen, Luukas; Miranda-Lourenco, Catarina; Fonseca-Gomes, Joao; Tanqueiro, Sara R.; Vaz, Sandra H.; Belo, Rita F.; Sebastiao, Ana Maria; Leinonen, Ville; Soininen, Hilkka; Pike, Ian; Haapasalo, Annakaisa; Lopes, Luisa V.; de Mendonca, Alexandre; Diogenes, Maria Jose; Hiltunen, Mikko
Alzheimer's genetic risk factor FERMT2 (Kindlin-2) controls axonal growth and synaptic plasticity in an APP-dependent manner (Nov, 10.1038/s41380-020-00926-w, 2020)
MOLECULAR PSYCHIATRY
IF10.1
2021-01-042
OAAI
Eysert, Fanny; Coulon, Audrey; Boscher, Emmanuelle; Vreulx, Anais-Camille; Flaig, Amandine; Mendes, Tiago; Hughes, Sandrine; Grenier-Boley, Benjamin; Hanoulle, Xavier; Demiautte, Florie; Bauer, Charlotte; Marttinen, Mikael; Takalo, Mari; Amouyel, Philippe; Desai, Shruti; Pike, Ian; Hiltunen, Mikko; Checler, Frederic; Farinelli, Melissa; Delay, Charlotte; Malmanche, Nicolas; Hebert, Sebastien S.; Dumont, Julie; Kilinc, Devrim; Lambert, Jean-Charles; Chapuis, Julien
Diabetic phenotype in mouse and humans reduces the number of microglia around β-amyloid plaques
MOLECULAR NEURODEGENERATION
IF17.5
2020-11-1026
OAAI
Natunen, Teemu; Martiskainen, Henna; Marttinen, Mikael; Gabbouj, Sami; Koivisto, Hennariikka; Kemppainen, Susanna; Kaipainen, Satu; Takalo, Mari; Svobodova, Helena; Leppanen, Luukas; Kemilainen, Benjam; Ryhanen, Simo; Kuulasmaa, Teemu; Rahunen, Eija; Juutinen, Sisko; Makinen, Petra; Miettinen, Pasi; Rauramaa, Tuomas; Pihlajamaki, Jussi; Haapasalo, Annakaisa; Leinonen, Ville; Tanila, Heikki; Hiltunen, Mikko
Alzheimer's genetic risk factor FERMT2 (Kindlin-2) controls axonal growth and synaptic plasticity in an APP-dependent manner

阿尔茨海默氏症的遗传危险因子FERMT2 (Kindlin-2) 以APP依赖性方式控制轴突生长和突触可塑性

MOLECULAR PSYCHIATRY
IF10.1
2020-11-0330
OAAI
Eysert, Fanny; Coulon, Audrey; Boscher, Emmanuelle; Flaig, Amandine; Mendes, Tiago; Hughes, Sandrine; Grenier-Boley, Benjamin; Hanoulle, Xavier; Demiautte, Florie; Bauer, Charlotte; Marttinen, Mikael; Takalo, Mari; Amouyel, Philippe; Desai, Shruti; Pike, Ian; Hiltunen, Mikko; Checler, Frederic; Farinelli, Melissa; Delay, Charlotte; Malmanche, Nicolas; Hebert, Sebastien S.; Dumont, Julie; Kilinc, Devrim; Lambert, Jean-Charles; Chapuis, Julien
BIN1 recovers tauopathy-induced long-term memory deficits in mice and interacts with Tau through Thr348 phosphorylation
ACTA NEUROPATHOLOGICA
IF9.3
2019-05-0738
OAAI
Sartori, Maxime; Mendes, Tiago; Desai, Shruti; Lasorsa, Alessia; Herledan, Adrien; Malmanche, Nicolas; Makinen, Petra; Marttinen, Mikael; Malki, Idir; Chapuis, Julien; Flaig, Amandine; Vreulx, Anais-Camille; Ciancia, Marion; Amouyel, Philippe; Leroux, Florence; Deprez, Benoit; Cantrelle, Francois-Xavier; Marechal, Damien; Pradier, Laurent; Hiltunen, Mikko; Landrieu, Isabelle; Kilinc, Devrim; Herault, Yann; Laporte, Jocelyn; Lambert, Jean-Charles

研究方向

暂未获取到该数据
A
Annakaisa Haapasalo
H 指数:48论文数:184被引数:1.7万
M
Mari Takalo
H 指数:19论文数:65被引数:4,111
M
Mikko Hiltunen
H 指数:59论文数:294被引数:3.2万
P
Petra Mäkinen
H 指数:21论文数:88被引数:1,304
T
Teemu Natunen
H 指数:21论文数:69被引数:1,642
V
Ville Leinonen
H 指数:47论文数:277被引数:7,900
H
Hilkka Soininen
H 指数:144论文数:1,229被引数:10.9万
I
Ian Pike
H 指数:36论文数:124被引数:4,522
T
Tuomas Rauramaa
H 指数:28论文数:137被引数:3,595
S
Susanna Kemppainen
H 指数:16论文数:45被引数:1,188