Stephan Krähenbühl - Publications, H-index & Citations

Stephan Krähenbühl

university hospital basel

57H指数

264论文数

1.1W被引数

收录论文 108

发表时间

Metformin - mechanisms of its glycemia-reducing effect 二甲双胍——其降糖作用的机制

Pharmacological Reviews

IF17.3

2025-11-20

PREAI

Jürgen Drewe; Marc Foretz; Stephan Krähenbühl

Relationship between simvastatin pharmacokinetics and muscle toxicity in male mice 他汀类药物辛伐他汀药代动力学与雄性小鼠肌肉毒性的关系

Food and Chemical Toxicology

IF3.5

2025-08-05

PREAI

Jamal Bouitbir; Gerda M. Sanvee; Miljenko V. Panajatovic; Natasha Bärenzung Fehrenbach; Théo Fréchard; Madhuri Manivannan; Urs Duthaler; Stephan Krähenbühl

Imatinib disturbs lysosomal function and morphology and impairs the activity of mTORC1 in human hepatocyte cell lines

FOOD AND CHEMICAL TOXICOLOGY

IF3.5

2022-04-01

OAAI

Roos, Noemi Johanna; Mancuso, Riccardo Vincenzo; Sanvee, Gerda Mawududzi; Bouitbir, Jamal; Krahenbuhl, Stephan

Cytochrome P450 1A2 is the most important enzyme for hepatic metabolism of the metamizole metabolite 4-methylaminoantipyrine

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

IF3

2021-11-07

OAAI

Bachmann, Fabio; Zu Schwabedissen, Henriette E. Meyer; Duthaler, Urs; Kraehenbuehl, Stephan

mTORC2 is an important target for simvastatin-associated toxicity in C2C12 cells and mouse skeletal muscle - Roles of Rap1 geranylgeranylation and mitochondrial dysfunction mTORC2是C2C12细胞和小鼠骨骼肌中辛伐他汀相关毒性的重要靶标-Rap1香耳根化和线粒体功能障碍的作用

BIOCHEMICAL PHARMACOLOGY

IF5.6

2021-10-01

OAAI

Sanvee, Gerda M.; Hitzfeld, Leonie; Bouitbir, Jamal; Krahenbuhl, Stephan

C2C12 myoblasts are more sensitive to the toxic effects of simvastatin than myotubes and show impaired proliferation and myotube formation

BIOCHEMICAL PHARMACOLOGY

IF5.6

2021-08-01

OAAI

Sanvee, Gerda M.; Bouitbir, Jamal; Krahenbuhl, Stephan

Effect of deglucuronidation on the results of the Basel phenotyping cocktail 去葡萄糖醛酸化对巴塞尔表型鸡尾酒结果的影响

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

IF3

2021-05-07

OAAI

Bachmann, Fabio; Duthaler, Urs; Krahenbuhl, Stephan

The pharmacokinetics and drug-drug interactions of ivermectin in Aedes aegypti mosquitoes

PLOS PATHOGENS

IF4.9

2021-03-17

OAAI

Duthaler, Urs; Weber, Michael; Hofer, Lorenz; Chaccour, Carlos; Maia, Marta; Muller, Pie; Krahenbuhl, Stephan; Hammann, Felix

Particle Forming Amorphous Solid Dispersions: A Mechanistic Randomized Pharmacokinetic Study in Humans 形成颗粒的无定形固体分散体: 在人类中的机械随机药代动力学研究

PHARMACEUTICS

IF5.5

2021-03-17

OAAI

Schittny, Andreas; Waldner, Samuel; Duthaler, Urs; Vorobyev, Alexander; Abramovich, Rimma; Krahenbuhl, Stephan; Puchkov, Maxim; Huwyler, Jorg

The Risk of Muscular Events Among New Users of Hydrophilic and Lipophilic Statins: an Observational Cohort Study

JOURNAL OF GENERAL INTERNAL MEDICINE

IF4.2

2021-03-09

OAAI

Mueller, Alexandra M.; Liakoni, Evangelia; Schneider, Cornelia; Burkard, Theresa; Jick, Susan S.; Kraehenbuehl, Stephan; Meier, Christoph R.; Spoendlin, Julia

Influence of Antihypertensive Treatment on RAAS Peptides in Newly Diagnosed Hypertensive Patients

CELLS

IF5.2

2021-03-03

OAAI

Vischer, Annina S.; Kuster, Gabriela M.; Twerenbold, Raphael; Pfister, Otmar; Zhou, Qian; Villiger, Andrea; Poglitsch, Marko; Krahenbuhl, Stephan; Mayr, Michael; Osswald, Stefan; Haschke, Manuel; Burkard, Thilo

Effects of Hypericum perforatum (St John's wort) on the pharmacokinetics and pharmacodynamics of rivaroxaban in humans

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

IF3

2020-10-25

OAAI

Scholz, Irene; Liakoni, Evangelia; Hammann, Felix; Grafinger, Katharina Elisabeth; Duthaler, Urs; Nagler, Michael; Kraehenbuhl, Stephan; Haschke, Manuel

In VitrotoIn VivoExtrapolation of Metabolic Clearance for UGT Substrates Using Short-Term Suspension and Long-Term Co-cultured Human Hepatocytes

AAPS JOURNAL

IF3.7

2020-10-13

PREAI

Docci, Luca; Klammers, Florian; Ekiciler, Aynur; Molitor, Birgit; Umehara, Kenichi; Walter, Isabelle; Kraehenbuehl, Stephan; Parrott, Neil; Fowler, Stephen

Construction and Verification of Physiologically Based Pharmacokinetic Models for Four Drugs Majorly Cleared by Glucuronidation: Lorazepam, Oxazepam, Naloxone, and Zidovudine

AAPS JOURNAL

IF3.7

2020-10-08

PREAI

Docci, Luca; Umehara, Kenichi; Kraehenbuehl, Stephan; Fowler, Stephen; Parrott, Neil

Simvastatin Impairs Glucose Homeostasis in Mice Depending on PGC-1α Skeletal Muscle Expression

BIOMEDICINES

IF3.9

2020-09-15

OAAI

Panajatovic, Miljenko Valentin; Singh, Francois; Krahenbuhl, Stephan; Bouitbir, Jamal