Philip A. Cole - Publications, H-index & Citations

Philip A. Cole

Harvard University

89H指数

536论文数

3.2W被引数

收录论文 195

发表时间

Histone modification cross-talk: analytical tools and molecular mechanisms 组蛋白修饰串扰：分析工具与分子机制

Biochemical Journal

IF4.3

2026-05-01

PREAI

Jiang, Jennifer; DuBois-Coyne, Sarah; Nam, Eunju; Whedon, Samuel D.; Lee, Kwangwoon; Cole, Philip A.

Genetic mutations and inhibitors of p300 and CBP p300和CBP的基因突变及抑制剂

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

IF0

2026-04-28

PREAI

Agnieszka Robaszkiewicz; Philip A. Cole

Interaction of NDRG1 and MRE11 Modulates DNA Replication and Repair NDRG1与MRE11的相互作用调控DNA复制与修复

Cancers

IF4.4

2026-04-21

OAAI

Hanna M. Doh; Nina Kozlova; Zhipeng A. Wang; Hwan Bae; Philip A. Cole; Taru Muranen

Cancer-associated fibroblasts regulate DNA repair in pancreatic cancer through NDRG1-mediated R-loop processing 癌症相关成纤维细胞通过NDRG1介导的R环处理调控胰腺癌的DNA修复

Nature Cell Biology

IF19.1

2026-04-01

PREAI

Kozlova, Nina; Cruz, Kayla A.; Ruzette, Antoine A.; Doh, Hanna M.; Willis, Nicholas A.; Hong, Su Min; Gonzalez, Raul S.; Vyas, Monika; Selfors, Laura M.; Dreyer, Stephan; Upstill-Goddard, Rosie; Faia, Kerrie L.; Wenglowsky, Steve; Close, Josh; Beutel, Alica; Jutric, Zeljka; Oliphant, Michael U. J.; Poluben, Larysa; Thapa, Byanjana; Taylor, Martin S.; Mustonen, Venla; Mangalath, Pradeep; Halbrook, Christopher J.; Grossman, Joseph E.; Hwang, Rosa F.; Clohessy, John G.; Ruskamo, Salla; Kursula, Petri; Petrova, Boryana; Kanarek, Naama; Cole, Philip A.; Chang, David K.; Evans, Conor L.; Norrelykke, Simon F.; Scully, Ralph; Muranen, Taru

Structural basis for the recruitment and selective phosphorylation of Akt by mTORC2 mTORC2招募和选择性磷酸化Akt的结构基础

Science

IF45.8

2025-11-27

PREAI

Martin S. Taylor; Maggie Chen; Matthew Hancock; Maximilian Wranik; Bryant D. Miller; Timothy R. O’Meara; Brad A. Palanski; Scott B. Ficarro; Brian J. Groendyke; Yufei Xiang; Kazuma T. Kondo; Karen Y. Linde-Garelli; Michelle J. Lee; Dibyendu Mondal; Daniel Freund; Samantha Congreve; Kaay Matas; Maximiliaan Hennink; Kera Xibinaku; Max L. Valenstein; Trevor van Eeuwen; Jarrod A. Marto; Andrej Sali; Yi Shi; Nathanael S. Gray; David M. Sabatini; Nam Chu; Kacper B. Rogala; Philip A. Cole

OBITUARY A tribute to Richard L. Maas (1954-2025)讣告献给Richard L. Maas（1954-2025）的致敬

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2025-11-17

PREAI

Haghighi, Alireza; Lachke, Salil A.; Frank, Natasha Y.; Goessling, Wolfram; Cole, Philip A.

Hydantion indolinones as AANAT inhibitors 咪唑并吲哚酮作为AANAT抑制剂

Bioorganic & Medicinal Chemistry Letters

IF2.2

2025-10-30

PREAI

Nicole Wandrey; Jake Boley; Dirce Gómez-Galicia; Mackinzi Hill; Mason Bach; Sidney Gawrych; Mackenzie Hagemeister; Philip A. Cole; Michael A. Moxley; Allen A. Thomas

DNA bendability regulates transcription factor binding to nucleosomes DNA的弯曲性调节转录因子与核小体的结合

Nature Structural & Molecular Biology

IF10.1

2025-08-25

PREAI

Luca Mariani; Xiao Liu; Kwangwoon Lee; Stephen S. Gisselbrecht; Philip A. Cole; Martha L. Bulyk

Biochemistry and regulation of histone lysine l-lactylation 组蛋白赖氨酸乳酰化的生物化学及其调控

Nature Reviews Molecular Cell Biology

IF90.2

2025-08-19

PREAI

Xinlei Sheng; Hening Lin; Philip A. Cole; Yingming Zhao

Biochemical analysis of PD-L1 ubiquitination by CRL3SPOP, ARIH1, and NEDD4 family ubiquitin ligases CRL3SPOP、ARIH1和NEDD4家族泛素连接酶介导的PD-L1泛素化生化分析

Structure

IF4.3

2025-06-04

PREAI

Guojiao Xie; Lin Gao; Renee Lu; Linxia Tian; Tiantian Zheng; Xinning Li; Yongjun Dang; Philip A. Cole; Xian Yu; Hanjie Jiang; Zan Chen

Deubiquitinase processing of a non-natural linkage of ubiquitinated-PTEN 泛素蛋白酶对泛素化-PTEN非自然连接位点的处理

BIOORGANIC CHEMISTRY

IF4.7

2025-04-01

PREAI

Iwase, Reina; Maisonet, Isabella Jaen; Lee, Kwangwoon; Buhrlage, Sara J.; Cole, Philip A.

A Small-Molecule Inhibitor of Gut Bacterial Urease Protects the Host from Liver Injury 肠道细菌尿素酶的小分子抑制剂保护宿主免受肝损伤

ACS CHEMICAL BIOLOGY

IF3.8

2025-01-08

PREAI

Richards-Corke, Khyle C.; Jiang, Yindi; Yeliseyev, Vladimir; Zhang, Yancong; Franzosa, Eric A.; Wang, Zhipeng A.; Abeywardana, Maheeshi Yapa; Cole, Phillip A.; Huttenhower, Curtis; Bry, Lynn; Balskus, Emily P.

Circular Engineered Sortase for Interrogating Histone H3 in Chromatin

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2024-11-25

OAAI

Whedon, Samuel D.; Lee, Kwangwoon; Wang, Zhipeng A.; Zahn, Emily; Lu, Congcong; Abeywardana, Maheeshi Yapa; Fairall, Louise; Nam, Eunju; DuBois-Coyne, Sarah; De Ioannes, Pablo; Sheng, Xinlei; Andrei, Adelina; Lundberg, Emily; Jiang, Jennifer; Armache, Karim-Jean; Zhao, Yingming; Schwabe, John W. R.; Wu, Mingxuan; Garcia, Benjamin A.; Cole, Philip A.

Targeting lysine acetylation readers and writers

NATURE REVIEWS DRUG DISCOVERY

IF101.8

2024-11-21

PREAI

Zhou, Ming-Ming; Cole, Philip A.

Multifaceted regulation of sirtuin 2 (Sirt2) deacetylase activity

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2024-09-01

OAAI

Abeywardana, Maheeshi Yapa; Whedon, Samuel D.; Lee, Kwangwoon; Nam, Eunju; Dovarganes, Rafael; DuBois-Coyne, Sarah; Haque, Ishraq A.; Wang, Zhipeng A.; Cole, Philip A.

Protein semisynthesis reveals plasticity in HECT E3 ubiquitin ligase mechanisms

NATURE CHEMISTRY

IF20.2

2024-07-19

PREAI

Jiang, Hanjie; Miller, Bryant D.; Viennet, Thibault; Kim, Hyojeon; Lee, Kwangwoon; Arthanari, Haribabu; Cole, Philip A.

Uncoupling histone modification crosstalk by engineering lysine demethylase LSD1

NATURE CHEMICAL BIOLOGY

IF13.7

2024-07-04

PREAI

Lee, Kwangwoon; Barone, Marco; Waterbury, Amanda L.; Jiang, Hanjie; Nam, Eunju; DuBois-Coyne, Sarah E.; Whedon, Samuel D.; Wang, Zhipeng A.; Caroli, Jonatan; Neal, Katherine; Ibeabuchi, Brian; Dhoondia, Zuzer; Kuroda, Mitzi I.; Liau, Brian B.; Beck, Samuel; Mattevi, Andrea; Cole, Philip A.

A MOZ-TIF2 leukemia mouse model displays KAT6-dependent H3K23 propionylation and overexpression of a set of active developmental genes

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-06-18

OAAI

Smolko, Anne E.; Sullivan, Daniel W.; Olsen, Sarah Naomi; Kang, Hyuckjoon; Whedon, Samuel D.; Baell, Jonathan B.; Cole, Philip A.; Armstrong, Scott A.; Kuroda, Mitzi I.

TARGETING ATYPICAL TERATOID RHABDOID TUMORS USING A NOVEL BI-FUNCTIONAL COREST INHIBITOR

NEURO-ONCOLOGY

IF13.4

2024-06-18

OAAI

Geethadevi, Anupa; Collard, Marianne; Findlay, Tyler; Fisher, Robert; Vaidya, Nikhil; Deng, Yiming; Eberhart, Charles; Cole, Philip; Alani, Rhoda; Rubens, Jeffrey; Raabe, Eric

An autoinhibitory switch of the LSD1 disordered region controls enhancer silencing LSD1无序区的自抑制开关控制增强子沉默

MOLECULAR CELL

IF16.6

2024-06-01

PREAI

Waterbury, Amanda L.; Kwok, Hui Si; Lee, Ceejay; Narducci, Domenic N.; Freedy, Allyson M.; Su, Cindy; Raval, Shaunak; Reiter, Andrew H.; Hawkins, William; Lee, Kwangwoon; Li, Jiaming; Hoenig, Samuel M.; Vinyard, Michael E.; Cole, Philip A.; Hansen, Anders S.; Carr, Steven A.; Papanastasiou, Malvina; Liau, Brian B.

研究方向