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Nicolas Coquelle

Institut de Biologie Structurale
H指数:32
被引数:3,502

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Integrated structural dynamics uncover a new B12 photoreceptor activation mode

集成结构动力学揭示了一种新的B12感光器激活模式

Nature
IF48.5
2026-02-040
PRE
Advancing macromolecular structure determination with microsecond X-ray pulses at a 4th generation synchrotron

在第4代同步加速器上使用微秒x射线脉冲推进大分子结构测定

2025-01-071
OAAI
De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals
2022-07-2816
OAAI
Discovery of a Potent Dual Inhibitor of Acetylcholinesterase and Butyrylcholinesterase with Antioxidant Activity that Alleviates Alzheimer-like Pathology in Old APP/PS1 Mice
2020-12-2857
OA
Serial femtosecond crystallography on in vivo-grown crystals drives elucidation of mosquitocidal Cyt1Aa bioactivation cascade
2020-03-0227
OAAI
Photoswitching mechanism of a fluorescent protein revealed by time-resolved crystallography and transient absorption spectroscopy
2020-02-0658
OAAI
Design, biological evaluation and X-ray crystallography of nanomolar multifunctional ligands targeting simultaneously acetylcholinesterase and glycogen synthase kinase-3
2019-04-0154
OAAI
The Magic of Crystal Structure-Based Inhibitor Optimization: Development of a Butyrylcholinesterase Inhibitor with Picomolar Affinity and in Vivo Activity
2017-12-22129
PREAI
Chromophore twisting in the excited state of a photoswitchable fluorescent protein captured by time-resolved serial femtosecond crystallography
2017-09-11165
OAAI
Development of an in-vivo active reversible butyrylcholinesterase inhibitor
2016-12-21132
OAAI