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收藏分享 收藏 Radioiodination of Two Carborane-Based Dual Cyclooxygenase-2/5-Lipoxygenase Inhibitors and Their In Vitro and In Vivo Evaluation两种碳硼烷基双环氧化酶-2/5-脂氧合酶抑制剂的放射性碘标记及其体外和体内评价
Schadlich, Jonas; Ullrich, Martin; Haase-Kohn, Cathleen; Wodtke, Robert; Braun, Sebastian; Molitor, Maximilian; Hofmann, Bettina; Steinhilber, Dieter; Kopka, Klaus; Hey-Hawkins, Evamarie; Pietzsch, Jens; Laube, Markus 分享 收藏 Exploiting the 2-(1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetic Acid Scaffold to Generate COXTRANs: A New Class of Dual Cyclooxygenase Inhibitors-Thromboxane Receptor AntagonistsBlua, Federica; Boccato, Francesca; Buccellati, Carola; Rise, Patrizia; Barbieri, Silvia; Castiglioni, Laura; Balzulat, Annika; Rolando, Barbara; Marini, Elisabetta; Balestra, Marta; Introvigne, Maria Luisa; Giorgis, Marta; Sironi, Luigi; Tacconelli, Stefania; Hiesinger, Kerstin; Patrignani, Paola; Schmidtko, Achim; Steinhilber, Dieter; Proschak, Ewgenij; Sala, Angelo; Rovati, G. Enrico; Bertinaria, Massimo 分享 收藏 分享 收藏 分享 收藏 分享 收藏 分享 收藏 Analysis of fatty acid-derived lipids in critically ill patients after cardiac surgery yields novel pathophysiologically relevant mediators with possible relevance for systemic inflammatory reactionsNeb, Holger; Roth, Verena; Roos, Jessica; Bauer, Tom; Urbschat, Anja; Heinicke, Ulrike; Angioni, Carlo; Steinhilber, Dieter; Piesche, Matthias; Ferreiros, Nerea; Gurke, Robert; Geisslinger, Gerd; Utech, Edith; Zacharowski, Kai; Meybohm, Patrick; Paulus, Patrick; Schmitt, Elke; Maier, Thorsten Juergen 分享 收藏 Development of a Potent and Selective G2A (GPR132) AgonistHernandez-Olmos, Victor; Heering, Jan; Marinescu, Beatrice; Schermeng, Tina; Ivanov, Vladimir V.; Moroz, Yurii S.; Nevermann, Sheila; Mathes, Marius; Ehrler, Johanna H. M.; Alnouri, Mohamad Wessam; Wolf, Markus; Haydo, Alicia S.; Schmachtel, Tessa; Zaliani, Andrea; Ho''fner, Georg; Kaiser, Astrid; Schubert-Zsilavecz, Manfred; Beck-Sickinger, Annette G.; Offermanns, Stefan; Gribbon, Philipp; Rieger, Michael A.; Merk, Daniel; Sisignano, Marco; Steinhilber, Dieter; Proschak, Ewgenij 分享 收藏 分享 收藏 Discovery of a Small Molecule Activator of Slack (Kcnt1) Potassium Channels That Significantly Reduces Scratching in Mouse Models of Histamine-Independent and Chronic ItchBalzulat, Annika; Zhu, W. Felix; Flauaus, Cathrin; Hernandez-Olmos, Victor; Heering, Jan; Sethumadhavan, Sunesh; Dubiel, Mariam; Frank, Annika; Menge, Amelie; Hebchen, Maureen; Metzner, Katharina; Lu, Ruirui; Lukowski, Robert; Ruth, Peter; Knapp, Stefan; Mueller, Susanne; Steinhilber, Dieter; Haenelt, Inga; Stark, Holger; Proschak, Ewgenij; Schmidtko, Achim 分享 收藏 Endogenous anti-tumorigenic nitro-fatty acids inhibit the ubiquitin-proteasome system by directly targeting the 26S proteasomeBrat, Camilla; Phuoc, Hai Phong Huynh; Awad, Omar; Parmar, Bhavesh S.; Hellmuth, Nadine; Heinicke, Ulrike; Amr, Shady; Grimmer, Jennifer; Surun, Duran; Husnjak, Koraljka; Carlsson, Max; Fahrer, Joerg; Bauer, Tom; Krieg, Sara-Cathrin; Manolikakes, Georg; Zacharowski, Kai; Steinhilber, Dieter; Muench, Christian; Maier, Thorsten Juergen; Ross, Jessica 分享 收藏 分享 收藏 Synthesis and In Vitro Biological Evaluation of p-Carborane-Based Di-tert-butylphenol AnalogsBraun, Sebastian; Jelaca, Sanja; Laube, Markus; George, Sven; Hofmann, Bettina; Loennecke, Peter; Steinhilber, Dieter; Pietzsch, Jens; Mijatovic, Sanja; Maksimovic-Ivanic, Danijela; Hey-Hawkins, Evamarie 分享 收藏 Carborane-Based Tebufelone Analogs and Their Biological Evaluation In VitroBraun, Sebastian; Paskas, Svetlana; Laube, Markus; George, Sven; Hofmann, Bettina; Loennecke, Peter; Steinhilber, Dieter; Pietzsch, Jens; Mijatovic, Sanja; Maksimovic-Ivanic, Danijela; Hey-Hawkins, Evamarie 分享 收藏 In Vitro Cytostatic Effect on Tumor Cells by Carborane-Based Dual Cyclooxygenase-2 and 5-Lipoxygenase InhibitorsBraun, Sebastian; Paskas, Svetlana; Laube, Markus; George, Sven; Hofmann, Bettina; Loennecke, Peter; Steinhilber, Dieter; Pietzsch, Jens; Mijatovic, Sanja S.; Maksimovic-Ivanic, Danijela; Hey-Hawkins, Evamarie 分享 收藏 分享 收藏 Biosynthesis of prostaglandin 15dPGJ2 -glutathione and 15dPGJ2-cysteine conjugates in macrophages and mast cells via MGST3Steinmetz-Spah, Julia; Liu, Jianyang; Singh, Rajkumar; Ekoff, Maria; Boddul, Sanjaykumar; Tang, Xiao; Bergqvist, Filip; Idborg, Helena; Heitel, Pascal; Ronnberg, Elin; Merk, Daniel; Wermeling, Fredrik; Haeggstrom, Jesper Z.; Nilsson, Gunnar; Steinhilber, Dieter; Larsson, Karin; Korotkova, Marina; Jakobsson, Per-Johan 分享 收藏 Compilation and evaluation of a fatty acid mimetics screening libraryEhrler, Johanna H. M.; Brunst, Steffen; Tjaden, Amelie; Kilu, Whitney; Heering, Jan; Hernandez-Olmos, Victor; Krommes, Andre; Kramer, Jan S.; Steinhilber, Dieter; Schubert-Zsilavecz, Manfred; Muller, Susanne; Merk, Daniel; Proschak, Ewgenij 分享 收藏 
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