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H

Howard S. Young

University of Alberta
H指数:45
被引数:5,254

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SARS-CoV-2 Mpro Protease Variants of Concern Display Altered Viral Substrate and Cell Host Target Galectin-8 Processing but Retain Sensitivity toward Antivirals
ACS CENTRAL SCIENCE
IF10.4
2023-03-2124
OAAI
Chen, Sizhu Amelia; Arutyunova, Elena; Lu, Jimmy; Khan, Muhammad Bashir; Rut, Wioletta; Zmudzinski, Mikolaj; Shahbaz, Shima; Iyyathurai, Jegan; Moussa, Eman W.; Turner, Zoe; Bai, Bing; Lamer, Tess; Nieman, James A.; Vederas, John C.; Julien, Olivier; Drag, Marcin; Elahi, Shokrollah; Young, Howard S.; Lemieux, M. Joanne
Improved SARS-CoV-2 Mpro inhibitors based on feline antiviral drug GC376: Structural enhancements, increased solubility, and micellar studies
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
2021-10-0171
OAAI
Vuong, Wayne; Fischer, Conrad; Khan, Muhammad Bashir; van Belkum, Marco J.; Lamer, Tess; Willoughby, Kurtis D.; Lu, Jimmy; Arutyunova, Elena; Joyce, Michael A.; Saffran, Holly A.; Shields, Justin A.; Young, Howard S.; Nieman, James A.; Tyrrell, D. Lorne; Lemieux, M. Joanne; Vederas, John C.
Peptidomimetic α-Acyloxymethylketone Warheads with Six-Membered Lactam P1 Glutamine Mimic: SARS-CoV-2 3CL Protease Inhibition, Coronavirus Antiviral Activity, and in Vitro Biological Stability
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2021-07-0975
PREAI
Bai, Bing; Belovodskiy, Alexandr; Hena, Mostofa; Kandadai, Appan Srinivas; Joyce, Michael A.; Saffran, Holly A.; Shields, Justin A.; Khan, Muhammad Bashir; Arutyunova, Elena; Lu, Jimmy; Bajwa, Sardeev K.; Hockman, Darren; Fischer, Conrad; Lamer, Tess; Vuong, Wayne; van Belkum, Marco J.; Gu, Zhengxian; Lin, Fusen; Du, Yanhua; Xu, Jia; Rahim, Mohammad; Young, Howard S.; Vederas, John C.; Tyrrell, D. Lorne; Lemieux, M. Joanne; Nieman, James A.
Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication (vol 11, 4282, 2020)

猫冠状病毒药物抑制SARS-CoV-2的主要蛋白酶并阻断病毒复制 (vol 11，4282，2020)

NATURE COMMUNICATIONS
IF15.7
2020-10-205
OAAI
Vuong, Wayne; Khan, Muhammad Bashir; Fischer, Conrad; Arutyunova, Elena; Lamer, Tess; Shields, Justin; Saffran, Holly A.; McKay, Ryan T.; van Belkum, Marco J.; Joyce, Michael A.; Young, Howard S.; Tyrrell, D. Lorne; Vederas, John C.; Lemieux, M. Joanne

研究方向

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M
M. Joanne Lemieux
H 指数:41论文数:210被引数:5,649
E
Elena Arutyunova
H 指数:20论文数:59被引数:1,842
J
John C. Vederas
H 指数:76论文数:524被引数:2.4万
T
Tess Lamer
H 指数:13论文数:29被引数:1,117
M
Muhammad Bashir Khan
H 指数:17论文数:55被引数:1,386
H 指数:0论文数:39被引数:400
D
David L. Stokes
H 指数:65论文数:438被引数:1.2万
J
Jimmy Lu
H 指数:7论文数:17被引数:440
J
Joseph O. Primeau
H 指数:5论文数:21被引数:334
P
Przemek A. Gorski
H 指数:14论文数:42被引数:1,116