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Identification and Characterization of a Blood-Brain Barrier Penetrant Inositol Hexakisphosphate Kinase (IP6K) Inhibitor Heitmann, Tyler; Liao, Gangling; Ernst, Glen; Poslusney, Michael; van Kralingen, Thomas; Li, Ye; Masi, Megan; Depasquale, Michael; Buchler, Ingrid; Wei, Huijun; Carr, Gregory V.; Shlevkov, Evgeny; Lu, Mengsi; Jessen, Henning; Barrow, James C. 分享 收藏
Mechanisms of therapeutic vulnerability of mismatch repair defective cancers to RNA polymerase I inhibitors Laiho, Marikki; Fan, Wenjun; Liu, Hester; Stachelek, Gregory C.; Begum, Asma; Davis, Catherine E.; Dorado, Tony; de Leon, Pablo; Rajeshkumar, N. V.; Barrow, James C. 分享 收藏
Fragment-Based Screening Identifies New Quinazolinone-Based Inositol Hexakisphosphate Kinase (IP6K) Inhibitors Heitmann, Tyler; Liao, Gangling; de Leon, Pablo; Ernst, Glen; Buchler, Ingrid; Wei, Huijun; Shlevkov, Evgeny; Brown, Dean; Fitzek, Martina; Collier, Matthew; Smith, David M.; Barrow, James C. 分享 收藏
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Discovery and Evaluation of Novel Angular Fused Pyridoquinazolinonecarboxamides as RNA Polymerase I Inhibitors Dorado, Tony E.; de Leon, Pablo; Begum, Asma; Liu, Hester; Chen, Daming; Rajeshkumar, N., V; Rey-Rodriguez, Romain; Hoareau-Aveilla, Coralie; Alcouffe, Chantal; Laiho, Marikki; Barrow, James C. 分享 收藏
Simplifying Submission Requirements for the Journal of Medicinal Chemistry 简化《药物化学杂志》的投稿要求 Lindsley, Craig W.; Barrow, James; Chibale, Kelly; Bolognesi, Maria Laura; Conway, Stuart; Denny, William; Ding, Ke; Laufer, Stefan; Lai, Luhua; Liu, Hong; Neamati, Nouri; Suzuki, Takayoshi; Meanwell, Nicholas; Young, Wendy 分享 收藏
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Inositol Pyrophosphates Mediate the DNA-PK/ATM-p53 Cell Death Pathway by Regulating CK2 Phosphorylation of Tti1/Tel2 (vol 54, pg 119, 2014) Rao, Feng; Cha, Jiyoung; Xu, Jing; Xu, Risheng; Vandiver, M. Scott; Tyagi, Richa; Tokhunts, Robert; Koldobskiy, Michael A.; Fu, Chenglai; Barrow, Roxanne; Wu, Mingxuan; Fiedler, Dorothea; Barrow, James C.; Snyder, Solomon H. 分享 收藏
Novel, non-nitrocatechol catechol-O-methyltransferase inhibitors modulate dopamine neurotransmission in the frontal cortex and improve cognitive flexibility Byers, Spencer; Buchler, Ingrid P.; DePasquale, Michael; Rowley, Helen L.; Kulkarni, Rajiv S.; Pinder, Lucy; Kolobova, Anna; Li, Cailian; Au, Vinh; Akuma, Daniel; Zhang, Gongliang; Wei, Huijun; Cheetham, Sharon C.; Barrow, James C.; Carr, Gregory V. 分享 收藏
Dissecting transcriptomic signatures of neuronal differentiation and maturation using iPSCs Burke, Emily E.; Chenoweth, Joshua G.; Shin, Joo Heon; Collado-Torres, Leonardo; Kim, Suel-Kee; Micali, Nicola; Wang, Yanhong; Colantuoni, Carlo; Straub, Richard E.; Hoeppner, Daniel J.; Chen, Huei-Ying; Sellers, Alana; Shibbani, Kamel; Hamersky, Gregory R.; Bustamante, Marcelo Diaz; Phan, BaDoi N.; Ulrich, William S.; Valencia, Cristian; Jaishankar, Amritha; Price, Amanda J.; Rajpurohit, Anandita; Semick, Stephen A.; Burli, Roland W.; Barrow, James C.; Hiler, Daniel J.; Page, Stephanie C.; Martinowich, Keri; Hyde, Thomas M.; Kleinman, Joel E.; Berman, Karen F.; Apud, Jose A.; Cross, Alan J.; Brandon, Nicholas J.; Weinberger, Daniel R.; Maher, Brady J.; McKay, Ronald D. G.; Jaffe, Andrew E. 分享 收藏
Synthesis and Evaluation of Bicyclic Hydroxypyridones as Inhibitors of Catechol O-Methyltransferase Ernst, Glen; Akuma, Daniel; Vinh Au; Buchler, Ingrid P.; Byers, Spencer; Carr, Gregory V.; Defays, Sabine; de Leon, Pablo; Demaude, Thierry; DePasquale, Michael; Durieu, Veronique; Huang, Yifang; Jigorel, Emilie; Kimos, Martha; Kolobova, Anna; Montel, Florian; Moureau, Florence; Poslusney, Michael; Swinnen, Dominique; Vandergeten, Marie-Christine; Van Houtvin, Nathalie; Wei, Huijun; White, Noelle; Wood, Martyn; Barrow, James C. 分享 收藏
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Optimization of 8-Hydroxyquinolines as Inhibitors of Catechol O-Methyltransferase Buchler, Ingrid; Akuma, Daniel; Au, Vinh; Carr, Gregory; de Leon, Pablo; DePasquale, Michael; Ernst, Glen; Huang, Yifang; Kimos, Martha; Kolobova, Anna; Poslusney, Michael; Wei, Huijun; Swinnen, Dominique; Montel, Florian; Moureau, Florence; Jigorel, Emilie; Schulze, Monika-Sarah E. D.; Wood, Martyn; Barrow, James C. 分享 收藏
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