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A

Andrew C. Hooker

uppsala university

27H指数
160论文数
4.9K被引数
收录论文 62
发表时间
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Optimizing Clinical Study Designs for CAR-T Cell Therapy: Development of an Efficient Sampling Strategy Through Optimal Experimental Design优化CAR-T细胞治疗的临床研究设计：通过最优实验设计开发高效的采样策略
errcpt: pharmacometrics & systems pharmacology
IF0
err2026-07-07
err0
errOAAI
errFenja Klima; Anna M. Mc Laughlin; Robin Michelet; Wilhelm Huisinga; Katy Haussmann; Annette Künkele; Andrew C. Hooker; Charlotte Kloft
err分享
err收藏
In Silico Clinical Trials in Drug Development: A Systematic Review计算机模拟临床试验在药物开发中的应用：系统综述
errTHERAPEUTIC INNOVATION & REGULATORY SCIENCE
IF1.9
err2025-11-01
err0
errOAAI
errChen, Bohua; Schneider, Lucia Chantal; Rover, Christian; Comets, Emmanuelle; Elze, Markus Christian; Hooker, Andrew; Inthout, Joanna; Jannot, Anne-Sophie; Julkowska, Daria; Mimouni, Yanis; Savelieva, Marina; Stallard, Nigel; Ursino, Moreno; Vandemeulebroecke, Marc; Weber, Sebastian; Posch, Martin; Zohar, Sarah; Friede, Tim
err分享
err收藏
A Pharmacometrics-Informed Trial Simulation Framework for Optimizing Study Designs for Disease-Modifying Treatments in Rare Neurological Disorders基于药代动力学信息指导的试验模拟框架，用于优化罕见神经系统疾病疾病修饰性治疗的研究设计
errcpt pharmacometrics systems pharmacology
IF0
err2025-08-05
err0
errOAAI
errYevgen Ryeznik; Ralf-Dieter Hilgers; Nicole Heussen; Emmanuelle Comets; France Mentré; Niels Hendrickx; Mats O. Karlsson; Andrew C. Hooker; Alzahra Hamdan; Xiaomei Chen; Rebecca Schüle; Matthis Synofzik; Oleksandr Sverdlov
err分享
err收藏
Integrated Modeling of Digital-Motor and Clinician-Reported Outcomes Using Item Response Theory: Towards Powerful Trials for Rare Neurological Diseases基于项目反应理论的数字-运动与临床报告结局的整合建模：面向罕见神经疾病的强力试验
errcpt pharmacometrics systems pharmacology
IF0
err2025-07-21
err0
errOAAI
errAlzahra Hamdan; Andreas Traschütz; Lukas Beichert; Xiaomei Chen; Cynthia Gagnon; Bart P. van de Warrenburg; Filippo M. Santorelli; Nazlı Başak; Giulia Coarelli; Rita Horvath; Stephan Klebe; PROSPAX consortium; EVIDENCE-RND consortium; Rebecca Schüle; Andrew C. Hooker; Matthis Synofzik; Mats O. Karlsson
err分享
err收藏
Leveraging Model Master Files for Long-Acting Injectables (Jan, 10.1007/s11095-025-03824-4, 2025)
errPHARMACEUTICAL RESEARCH
IF4.3
err2025-02-12
err0
errOAAI
errGong, Yuqing; Hopefl, Robert; Li, Tonglei; Hooker, Andrew C.; Silva, Daniela Amaral; Alam, Khondoker; Ducharme, Murray; Moody, Rebecca; Saha, Pratik; Babiskin, Andrew
err分享
err收藏
Leveraging Model Master Files for Long-Acting Injectables
errPHARMACEUTICAL RESEARCH
IF4.3
err2025-01-28
err1
errOAAI
errGong, Yuqing; Hopefl, Robert; Li, Tonglei; Hooker, Andrew C.; Silva, Daniela Amaral; Alam, Khondoker; Ducharme, Murray; Moody, Rebecca; Saha, Pratik; Babiskin, Andrew
err分享
err收藏
Synthetic T-Cell Receptor-like Protein Behaves as a Janus Particle in Solution
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2024-12-19
err0
errOAAI
errSakamoto-Rablah, Emily; Bye, Jordan; Modak, Arghya; Hooker, Andrew; Uddin, Shahid; Mcmanus, Jennifer J.
err分享
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Longitudinal Analysis of Natural History Progression of Rare and Ultra-Rare Cerebellar Ataxias Using Item Response Theory项目反应理论对罕见和超罕见小脑共济失调自然史进展的纵向分析
errCLINICAL PHARMACOLOGY & THERAPEUTICS
IF5.5
err2024-10-15
err1
errOAAI
errHamdan, Alzahra; Hendrickx, Niels; Hooker, Andrew C.; Chen, Xiaomei; Comets, Emmanuelle; Traschuetz, Andreas; Schuele, Rebecca; Mentre, France; Synofzik, Matthis; Karlsson, Mats O.
err分享
err收藏
Evaluation of model-integrated evidence approaches for pharmacokinetic bioequivalence studies using model averaging methods使用模型平均法评估药代动力学生物等效性研究的模型集成证据方法
errCPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY
IF3
err2024-08-28
err1
errOAAI
errNyberg, Henrik Bjugard; Chen, Xiaomei; Donnelly, Mark; Fang, Lanyan; Zhao, Liang; Karlsson, Mats O.; Hooker, Andrew C.
err分享
err收藏
A fully automatic tool for development of population pharmacokinetic models
errCPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY
IF3
err2024-08-27
err1
errOAAI
errChen, Xiaomei; Nordgren, Rikard; Belin, Stella; Hamdan, Alzahra; Wang, Shijun; Yang, Tianwu; Huang, Zhe; Carter, Simon J.; Buatois, Simon; Abrantes, Joao A.; Hooker, Andrew C.; Karlsson, Mats O.
err分享
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Development and comparison of model-integrated evidence approaches for bioequivalence studies with pharmacokinetic end points开发和比较具有药代动力学终点的生物等效性研究的模型集成证据方法
errCPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY
IF3
err2024-08-23
err0
errOAAI
errChen, Xiaomei; Nyberg, Henrik B.; Donnelly, Mark; Zhao, Liang; Fang, Lanyan; Karlsson, Mats O.; Hooker, Andrew C.
err分享
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The Role of Model Master Files for Sharing, Acceptance, and Communication with FDA
errAAPS JOURNAL
IF3.7
err2024-02-27
err8
PREAI
errFang, Lanyan; Gong, Yuqing; Hooker, Andrew C.; Lukacova, Viera; Rostami-Hodjegan, Amin; Sale, Mark; Grosser, Stella; Jereb, Rebeka; Savic, Rada; Peck, Carl; Zhao, Liang
err分享
err收藏
Liposomal encapsulation of amoxicillin via microfluidics with subsequent investigation of the significance of PEGylated therapeutics
errINTERNATIONAL JOURNAL OF PHARMACEUTICS
IF5.2
err2024-01-01
err3
errOAAI
errWeaver, Edward; Macartney, Robyn A.; Irwin, Robyn; Uddin, Shahid; Hooker, Andrew; Burke, George A.; Wylie, Matthew P.; Lamprou, Dimitrios A.
err分享
err收藏
Statistical recommendations for count, binary, and ordinal data in rare disease cross-over trials
errORPHANET JOURNAL OF RARE DISEASES
IF3.5
err2023-12-19
err0
errOAAI
errGeroldinger, Martin; Verbeeck, Johan; Hooker, Andrew C.; Thiel, Konstantin E.; Molenberghs, Geert; Nyberg, Joakim; Bauer, Johann; Laimer, Martin; Wally, Verena; Bathke, Arne C.; Zimmermann, Georg
err分享
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Optimizing the design of a pharmacokinetic trial to evaluate the dosing scheme of a novel tuberculosis drug in children living with or without HIV
errCPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY
IF3
err2023-11-17
err0
errOAAI
errMontepiedra, Grace; Svensson, Elin M.; Wong, Weng Kee; Hooker, Andrew C.
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Microfluidic encapsulation of enzymes and steroids within solid lipid nanoparticles
errDRUG DELIVERY AND TRANSLATIONAL RESEARCH
IF5.5
err2023-07-28
err3
errOAAI
errWeaver, Edward; Sommonte, Federica; Hooker, Andrew; Denora, Nunzio; Uddin, Shahid; Lamprou, Dimitrios A.
err分享
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Establishing the suitability of model-integrated evidence to demonstrate bioequivalence for long-acting injectable and implantable drug products: Summary of workshop
errCPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY
IF3
err2023-02-09
err9
errOAAI
errGong, Yuqing; Zhang, Peijue; Yoon, Miyoung; Zhu, Hao; Kohojkar, Ameya; Hooker, Andrew C.; Ducharme, Murray P.; Gobburu, Jogarao; Celliere, Geraldine; Gajjar, Parmesh; Li, Bing V.; Velagapudi, Raja; Tsang, Yu Chung; Schwendeman, Anna; Polli, James; Fang, Lanyan; Lionberger, Robert; Zhao, Liang
err分享
err收藏
Microfluidic-mediated self-assembly of phospholipids for the delivery of biologic molecules
errINTERNATIONAL JOURNAL OF PHARMACEUTICS
IF5.2
err2022-01-01
err19
errOAAI
errWeaver, Edward; O'Connor, Edward; Cole, David K.; Hooker, Andrew; Uddin, Shahid; Lamprou, Dimitrios A.
err分享
err收藏
Metaheuristics for pharmacometrics
errCPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY
IF3
err2021-10-22
err3
errOAAI
errKim, Seongho; Hooker, Andrew C.; Shi, Yu; Kim, Grace Hyun J.; Wong, Weng Kee
err分享
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Tutorial for $DESIGN in NONMEM: Clinical trial evaluation and optimization
errCPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY
IF3
err2021-10-19
err8
errOAAI
errBauer, Robert J.; Hooker, Andrew C.; Mentre, France
err分享
err收藏

研究方向

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合作学者
合作期刊
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Jaap Verweij
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Geert Molenberghs
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Bengt Långström
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