Zhizhou Fang - Publications, H-index & Citations

Zhizhou Fang

merck kgaa

10H指数

21论文数

495被引数

收录论文 13

发表时间

Evaluation of the Disconnect between Hepatocyte and Microsome Intrinsic Clearance at intracellular and extracellular pH 评价细胞内和细胞外pH条件下肝细胞与微粒体固有清除率之间的差异

Drug Metabolism and Disposition

IF4

2026-04-01

PREAI

Christine Katharina Maurer; Zhizhou Fang; Stephanie Harlfinger; Carl Petersson

Drug-Drug Interaction Assessments of Clinical Transporter Inhibition: Learnings from the Transporter Working Group from the International Consortium for Innovation and Quality in Pharmaceutical Development 药物-药物相互作用评估的临床转运蛋白抑制作用：国际制药开发创新与质量联盟转运蛋白工作组的学习总结

Drug Metabolism and Disposition

IF4

2026-02-24

PREAI

Rucha S. Sane; Pallabi Mitra; Yurong Lai; Cindy Yanfei Li; Hong Shen; Kimio Tohyama; Chester Costales; Laurent Salphati; Kelly M. Mahar; Daniel A.J. Bow; James M. Vergis; Jochen Brumm; Kunal Taskar; Hugues Chanteux; Zhizhou Fang; Xiaomin Liang; Seong Hee Park; Imad Hanna; Nilay Thakkar; Xiaoyan Chu

Precipitation as Key Parameter for Early Oral Drug Absorption Predictions, Part I: Acquisition of critical data 降水作为早期口服药物吸收预测的关键参数，第一部分：关键数据的获取

European Journal of Pharmaceutical Sciences

IF4.7

2025-07-19

PREAI

Sara Mayer; Christian Wagner; Andreas Lehmann; Zhizhou Fang; Werner Weitschies; Katharina Krollik

Beyond-Rule-of-Five Compounds Are Not Different: In Vitro-In Vivo Extrapolation of Female CD-1 Mouse Clearance Based on Merck Healthcare KGaA Compound Set 超出“五规则”的化合物并无差异：基于Merck Healthcare KGaA化合物集对雌性CD-1小鼠清除率的体外-体内外推研究

PHARMACEUTICALS

IF4.8

2025-04-14

OAAI

Maurer, Christine K.; Fang, Zhizhou; Duevel, Heide M.; Harlfinger, Stephanie

In vitro and in vivo ADME of heterobifunctional degraders: a tailored approach to optimize DMPK properties of PROTACs©

RSC MEDICINAL CHEMISTRY

IF3.6

2025-01-01

PREAI

Maurer, Christine Katharina; Fang, Zhizhou; Schindler, Christina; Pohl, Gianna; Machrouhi-Porcher, Fouzia; Lecomte, Marc; Petersson, Carl; Duevel, Heide Marika

Discovery of quinazoline HPK1 inhibitors with high cellular potency

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2023-09-01

PREAI

Toure, Momar; Johnson, Theresa; Li, Bin; Schmidt, Ralf; Ma, Hong; Neagu, Constantin; Lopez, Andrea Unzue; Wang, Yanping; Guler, Satenig; Xiao, YuFang; Henkes, Renate; Ho, Kevin; Zhang, Susan; Chu, Chia Lin; Gundra, Uma Mahesh; Porichis, Filippos; Li, Long; Maurer, Christine Katharina; Fang, Zhizhou; Musil, Djordje; DiPoto, Maria; Friis, Emily; Jones, Reinaldo; Jones, Christopher; Cummings, James; Chekler, Eugene; Tanzer, Eva Maria; Huck, Bayard; Sherer, Brian

Discovery of Covalent Bruton's Tyrosine Kinase Inhibitors with Decreased CYP2C8 Inhibitory Activity

CHEMMEDCHEM

IF3.4

2021-10-08

PREAI

Qiu, Hui; Ali, Zahid; Bowlan, Julian; Caldwell, Richard; Gardberg, Anna; Glaser, Nina; Goutopoulos, Andreas; Head, Jared; Johnson, Theresa; Maurer, Christine; Georgi, Katrin; Grenningloh, Roland; Fang, Zhizhou; Morandi, Federica; Rohdich, Felix; Schmidt, Ralf; Follis, Ariele Viacava; Sherer, Brian

Discovery of potent and selective reversible Bruton?s tyrosine kinase inhibitors 发现有效和选择性的可逆布鲁顿酪氨酸激酶抑制剂

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2021-06-01

PREAI

Qiu, Hui; Ali, Zahid; Bender, Andrew; Caldwell, Richard; Chen, Yi-Ying; Fang, Zhizhou; Gardberg, Anna; Glaser, Nina; Goettsche, Anja; Goutopoulos, Andreas; Grenningloh, Roland; Hanschke, Bettina; Head, Jared; Johnson, Theresa; Jones, Christopher; Jones, Reinaldo; Kulkarni, Shashank; Maurer, Christine; Morandi, Federica; Neagu, Constantin; Poetzsch, Sven; Potnick, Justin; Schmidt, Ralf; Roe, Katherine; Follis, Ariele Viacava; Wing, Carolyn; Zhu, Xiaohua; Sherer, Brian

Characterization and Validation of Canine P-Glycoprotein-Deficient MDCK II Cell Lines for Efflux Substrate Screening

PHARMACEUTICAL RESEARCH

IF4.3

2020-09-11

PREAI

Ye, Dong; Harder, Anna; Fang, Zhizhou; Weinheimer, Manuel; Laplanche, Loic; Mezler, Mario

Systematic Kinase Inhibitor Profiling Identifies CDK9 as a Synthetic Lethal Target in NUT Midline Carcinoma

CELL REPORTS

IF6.9

2017-09-01

OAAI

Braegelmann, Johannes; Dammert, Marcel A.; Dietlein, Felix; Heuckmann, Johannes M.; Choidas, Axel; Boehm, Stefanie; Richters, Andre; Basu, Debjit; Tischler, Verena; Lorenz, Carina; Habenberger, Peter; Fang, Zhizhou; Ortiz-Cuaran, Sandra; Leenders, Frauke; Eickhoff, Jan; Koch, Uwe; Getlik, Matthaeus; Termathe, Martin; Sallouh, Muhammad; Greff, Zoltan; Varga, Zoltan; Balke-Want, Hyatt; French, Christopher A.; Peifer, Martin; Reinhardt, H. Christian; Orfi, Laszlo; Keri, Gyorgy; Ansen, Sascha; Heukamp, Lukas C.; Buettner, Reinhard; Rauh, Daniel; Klebl, Bert M.; Thomas, Roman K.; Sos, Martin L.

Discovery of Inter-Domain Stabilizers-A Novel Assay System for Allosteric Akt Inhibitors

ACS CHEMICAL BIOLOGY

IF3.8

2014-07-03

PREAI

Fang, Zhizhou; Simard, Jeffrey R.; Plenker, Dennis; Nguyen, Hoang D.; Trang Phan; Wolle, Patrik; Baumeister, Stefan; Rauh, Daniel

Overcoming Compound Fluorescence in the FLiK Screening Assay with Red-Shifted Fluorophores

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2013-05-24

PREAI

Schneider, Ralf; Gohla, Anne; Simard, Jeffrey R.; Yadav, Dharmendra B.; Fang, Zhizhou; van Otterlo, Willem A. L.; Rauh, Daniel