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A

Aaron Balog

Bristol-Myers Squibb
H指数:28
被引数:3,238

个人简介

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教育背景

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工作经历

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荣誉奖项

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Development of a Stereoselective and Scalable Synthesis for the Potent Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitor, BMT-297376; N-((R)-1-((cis)-4-(3-(Difluoromethyl)-2-methoxypyridin-4-yl)cyclohexyl)propyl)-6-methoxynicotinamide
ORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
2021-06-292
PREAI
Nimje, Roshan Y.; Kuppusamy, Prakasam; Krishnamoorthy, Suresh; Shanmugam, Yoganand; Ramasamy, Duraisamy; Manoharan, Haridhas; Arunachalam, Pirama Nayagam; Balog, Aaron; Cherney, Emily C.; Zhang, Liping; Borzilleri, Robert M.; Hong, Zhenqiu; Kempson, James; Rampulla, Richard R.; Mathur, Arvind; Gupta, Anuradha
Conformational-Analysis-Guided Discovery of 2,3-Disubstituted Pyridine IDO1 Inhibitors

构象分析指导的2，3-二取代吡啶IDO1抑制剂的发现

ACS MEDICINAL CHEMISTRY LETTERS
IF4
2021-06-162
OAAI
Cherney, Emily C.; Zhang, Liping; Guo, Weiwei; Huang, Audris; Williams, David; Seitz, Steven; Shan, Weifang; Zhu, Xiao; Gullo-Brown, Johnni; Maley, Derrick; Lin, Tai-an; Hunt, John T.; Huang, Christine; Yang, Zheng; D'Arienzo, Celia J.; Discenza, Lorell N.; Ranasinghe, Asoka; Grubb, Mary F.; Traeger, Sarah C.; Li, Xin; Johnston, Kathy A.; Kopcho, Lisa; Fereshteh, Mark; Foster, Kimberly A.; Stefanski, Kevin; Delpy, Diane; Dhar, Gopal; Anandam, Aravind; Mahankali, Sandeep; Padmanabhan, Shweta; Rajanna, Prabhakar; Murali, Venkata; Mariappan, T. Thanga; Pattasseri, Shabeerali; Nimje, Roshan Y.; Hong, Zhenqiu; Kempson, James; Rampulla, Richard; Mathur, Arvind; Gupta, Anuradha; Borzilleri, Robert; Vite, Gregory; Balog, Aaron
Discovery of Imidazopyridines as Potent Inhibitors of Indoleamine 2,3-Dioxygenase 1 for Cancer Immunotherapy

咪唑并吡啶作为吲哚胺2，3-双加氧酶1的有效抑制剂用于癌症免疫治疗的发现

ACS MEDICINAL CHEMISTRY LETTERS
IF4
2021-03-0210
OA
Zhang, Liping; Cherney, Emily C.; Zhu, Xiao; Lin, Tai-an; Gullo-Brown, Johnni; Maley, Derrick; Johnston-Allegretto, Kathy; Kopcho, Lisa; Fereshteh, Mark; Huang, Christine; Li, Xin; Traeger, Sarah C.; Dhar, Gopal; Anandam, Aravind; Mahankali, Sandeep; Padmanabhan, Shweta; Rajanna, Prabhakar; Murali, Venkata; Mariappan, Thanga; Borzilleri, Robert; Vite, Gregory; Hunt, John T.; Balog, Aaron
Discovery and Preclinical Evaluation of BMS-986242, a Potent, Selective Inhibitor of Indoleamine-2,3-dioxygenase 1

BMS-986242的发现和临床前评估，一种有效的，选择性的Indoleamine-2，3-双加氧酶1抑制剂

ACS MEDICINAL CHEMISTRY LETTERS
IF4
2021-01-2820
OA
Cherney, Emily C.; Zhang, Liping; Nara, Susheel; Zhu, Xiao; Gullo-Brown, Johnni; Maley, Derrick; Lin, Tai-An; Hunt, John T.; Huang, Christine; Yang, Zheng; Darienzo, Celia; Discenza, Lorell; Ranasinghe, Asoka; Grubb, Mary; Ziemba, Theresa; Traeger, Sarah C.; Li, Xin; Johnston, Kathy; Kopcho, Lisa; Fereshteh, Mark; Foster, Kimberly; Stefanski, Kevin; Fargnoli, Joseph; Swanson, Jesse; Brown, Jennifer; Delpy, Diane; Seitz, Steven P.; Borzilleri, Robert; Vite, Gregory; Balog, Aaron
Immune-modulating enzyme indoleamine 2,3-dioxygenase is effectively inhibited by targeting its apo-form

免疫调节酶吲哚胺2，3-双加氧酶通过靶向其apo形式被有效抑制

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2018-03-12162
OAAI
Nelp, Micah T.; Kates, Patrick A.; Hunt, John T.; Newitt, John A.; Balog, Aaron; Maley, Derrick; Zhu, Xiao; Abell, Lynn; Allentoff, Alban; Borzilleri, Robert; Lewis, Hal A.; Lin, Zeyu; Seitz, Steven P.; Yan, Chunhong; Groves, John T.
Discovery of the Selective CYP17A1 Lyase Inhibitor BMS-351 for the Treatment of Prostate Cancer

用于治疗前列腺癌的选择性CYP17A1裂解酶抑制剂BMS-351的发现

ACS MEDICINAL CHEMISTRY LETTERS
IF4
2015-12-147
OAAI
Huang, Audris; Jayaraman, Lata; Fura, Aberra; Vite, Gregory D.; Trainor, George L.; Gottardis, Marco M.; Spires, Thomas E.; Spires, Vanessa M.; Rizzo, Cheryl A.; Obermeier, Mary T.; Elzinga, Paul A.; Todderud, Gordon; Fan, Yi; Newitt, John A.; Beyer, Sophie M.; Zhu, Yongxin; Warrack, Bethanne M.; Goodenough, Angela K.; Tebben, Andrew J.; Doweyko, Arthur M.; Gold, David L.; Balog, Aaron
Discovery of BMS-641988, a Novel Androgen Receptor Antagonist for the Treatment of Prostate Cancer
ACS MEDICINAL CHEMISTRY LETTERS
IF4
2015-06-2621
OAAI
Balog, Aaron; Rampulla, Richard; Martin, Gregory S.; Krystek, Stanley R.; Attar, Ricardo; Dell-John, Janet; DiMarco, John D.; Fairfax, David; Gougoutas, Jack; Hoist, Christian L.; Nation, Andrew; Rizzo, Cheryl; Rossiter, Lana M.; Schweizer, Liang; Shan, Weifang; Spergel, Steven; Spires, Thomas; Cornelius, Georgia; Gottardis, Marco; Trainor, George; Vite, Gregory D.; Salvatit, Mark E.
Discovery of Clinical Candidate BMS-906024: A Potent Pan-Notch Inhibitor for the Treatment of Leukemia and Solid Tumors
ACS MEDICINAL CHEMISTRY LETTERS
IF4
2015-03-1881
OAAI
Gavai, Ashvinikumar V.; Quesnelle, Claude; Norris, Derek; Han, Wen-Ching; Gill, Patrice; Shan, Weifang; Balog, Aaron; Chen, Ke; Tebben, Andrew; Rampulla, Richard; Wu, Dauh-Rurng; Zhang, Yingru; Mathur, Arvind; White, Ronald; Rose, Anne; Wang, Haiqing; Yang, Zheng; Ranasinghe, Asoka; D'Arienzo, Celia; Guarino, Victor; Xiao, Lan; Su, Ching; Everlof, Gerry; Arora, Vinod; Shen, Ding Ren; Cvijic, Mary Ellen; Menard, Krista; Wen, Mei-Li; Meredith, Jere; Trainor, George; Lombardo, Louis J.; Olson, Richard; Baran, Phil S.; Hunt, John T.; Vite, Gregory D.; Fischer, Bruce S.; Westhouse, Richard A.; Lee, Francis Y.
BMS-983970, an oral pan-Notch inhibitor for the treatment of cancer
CANCER RESEARCH
IF16.6
2014-10-011
PRE
Gavai, Ashvinikumar V.; Zhao, Yufen; O'Malley, Daniel; Fink, Brian; Quesnelle, Claude; Norris, Derek; Chen, Libing; Kim, Soong-Hoon; Han, Wen-Ching; Gill, Patrice; Shan, Weifang; Balog, Aaron; Tebben, Andrew; Rampulla, Richard; Wu, Dauh-Rurng; Zhang, Yingru; Mathur, Arvind; Wang, Haiqing; Yang, Zheng; Ruan, Qian; Moore, Robin; Rodrigues, David; Ranasinghe, Asoka; D'Arienzo, Celia; Tye, Ching Kim; Su, Ching; Everlof, Gerry; Yarde, Melissa; Cvijic, Mary Ellen; Menard, Krista; Wen, Mei-Li; Trainor, George; Fischer, Bruce; Hunt, John; Vite, Gregory; Westhouse, Richard; Lee, Francis
Androgen receptor antagonists: Lead optimization and preclinical pharmacology
CANCER RESEARCH
IF16.6
2010-04-010
PRE
Gavai, Ashvin; Norris, Derek; Balog, Aaron; Austin, Joel; Shan, Weifang; Zhao, Yufen; Han, Wen-Ching; Sharma, Lisa; Nation, Andrew; Wu, Dauh-Rurng; Mathur, Arvind; Zhang, Litai; Cvijic, Mary Ellen; Yarde, Melissa; Apanovitch, Donald; Twamley, Celeste; Tang, Yuwei; Johnson, Benjamin; Elzinga, Paul; Cornelius, Georgia; Obermeier, Mary; Foster, William; Marathe, Punit; Dell-John, Janet; Dito, Gennaro; Masters, Gregg; Rizzo, Cheryl; Schweizer, Liang; Jure-Kunkel, Maria; Attar, Ricardo; Gottardis, Marco; Vite, Gregory

研究方向

暂未获取到该数据
G
Gregory D. Vite
H 指数:36论文数:206被引数:4,563
J
John T. Hunt
H 指数:44论文数:190被引数:7,613
S
Samuel J. Danishefsky
H 指数:111论文数:1,329被引数:5.2万
W
Weifang Shan
H 指数:13论文数:40被引数:973
D
Derrick Maley
H 指数:10论文数:25被引数:695
T
Ting‐Chao Chou
H 指数:68论文数:536被引数:3.6万
A
Arvind Mathur
H 指数:32论文数:267被引数:3,448
M
Marco M. Gottardis
H 指数:54论文数:342被引数:8,951
R
R. M. Borzilleri
H 指数:33论文数:209被引数:5,381
T
Tai-an Lin
H 指数:8论文数:50被引数:320