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R

Radek Jorda

palacky university olomouc
H指数:24
被引数:1,608

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3H-pyrazolo[4,3-f]quinoline hinge binder, a tunable scaffold for development of novel kinase inhibitors against FLT3-driven leukemia

3H-吡唑并[4,3-f]喹啉铰链结合剂，一种可调骨架，用于开发针对FLT3驱动的白血病的创新激酶抑制剂

European Journal of Medicinal Chemistry
IF5.9
2025-10-290
OAAI
Neetu Dayal; Eva Řezníčková; Delmis E. Hernandez; Miroslav Peřina; Jakub Bělíček; Veronika Vojáčková; Petra Krňávková; Marek Bařina; Nickolas R. Brauer; Mandeep Kaur Hunjan; Pratik Yadav; Radek Jorda; Herman O. Sintim
New Inhibitors of Bcr-Abl Based on 2,6,9-Trisubstituted Purine Scaffold Elicit Cytotoxicity in Chronic Myeloid Leukemia-Derived Cell Lines Sensitive and Resistant to TKIs

基于2,6，9-三取代嘌呤支架的新型bcr-abl抑制剂在对TKIs敏感和耐药的慢性粒细胞白血病衍生细胞系中引起细胞毒性

PHARMACEUTICS
IF5.5
2024-05-110
OAAI
Delgado, Thalia; Vesela, Denisa; Dostalova, Hana; Krystof, Vladimir; Vojackova, Veronika; Jorda, Radek; Castro, Alejandro; Bertrand, Jeanluc; Rivera, Gildardo; Faundez, Mario; Strnad, Miroslav; Espinosa-Bustos, Christian; Salas, Cristian O.
Cyclin dependent kinase 4/6 inhibitor palbociclib synergizes with BCL2 inhibitor venetoclax in experimental models of mantle cell lymphoma without RB1 deletion

细胞周期蛋白依赖性激酶4/6抑制剂palbociclib与BCL2抑制剂venetoclax在无RB1缺失的套细胞淋巴瘤实验模型中协同作用

hematology oncology
IF13.5
2024-03-250
OAAI
Malarikova, Diana; Jorda, Radek; Kupcova, Kristyna; Senavova, Jana; Dolnikova, Alexandra; Pokorna, Eva; Kazantsev, Dmitry; Nozickova, Kristina; Sovilj, Dana; Bellanger, Celine; Chiron, David; Andera, Ladislav; Krystof, Vladimir; Strnad, Miroslav; Helman, Karel; Klanova, Magdalena; Trneny, Marek; Havranek, Ondrej; Klener, Pavel
Inhibition of FLT3-ITD Kinase in Acute Myeloid Leukemia by New Imidazo[1,2-b]pyridazine Derivatives Identified by Scaffold Hopping
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2023-08-035
OAAI
Brehova, Petra; Reznickova, Eva; Skach, Krystof; Jorda, Radek; Dejmek, Milan; Vojackova, Veronika; Sala, Michal; Kovalova, Marketa; Dracinsky, Martin; Dolnikova, Alexandra; Strmen, Timotej; Kinnertova, Monika; Chalupsky, Karel; Dvorakova, Alexandra; Gucky, Tomas; Kaiserova, Helena Mertlikova; Klener, Pavel; Nencka, Radim; Krystoy, Vladimir

研究方向

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V
Vladimı́r Kryštof
H 指数:38论文数:253被引数:5,190
E
Eva Řezníčková
H 指数:16论文数:85被引数:715
M
Miroslav Strnad
H 指数:86论文数:645被引数:2.8万
H 指数:0论文数:78被引数:673
V
Veronika Vojáčková
H 指数:8论文数:32被引数:226
M
Miroslav Peřina
H 指数:7论文数:39被引数:221
L
Libor Havlı́ček
H 指数:26论文数:99被引数:3,122
K
Karel Berka
H 指数:39论文数:238被引数:7,057
J
Jana Škerlová
H 指数:13论文数:65被引数:498
V
Václav Bazgier
H 指数:18论文数:43被引数:2,431