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Identification of furo[2,3-d]pyrimidin-4-ylsulfanyl-1,3,4-thiadiazole derivatives as novel FLT3-ITD inhibitors Moradi, Mahfam; Mousavi, Alireza; Reznickova, Eva; Peytam, Fariba; Perina, Miroslav; Vojackova, Veronika; Firoozpour, Loghman; Jorda, Radek; Gruz, Jiri; Emamgholipour, Zahra; Sadat-Ebrahimi, Seyed Esmaeil; Krystof, Vladimir; Foroumadi, Alireza 分享 收藏
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Synthesis and estrogenic activity of BODIPY-labeled estradiol conjugates Perina, Miroslav; Borzsei, Rita; Agoston, Henrietta; Hlogyik, Tamas; Poor, Miklos; Rigo, Reka; Ozvegy-Laczka, Csilla; Batta, Gyula; Hetenyi, Csaba; Vojackova, Veronika; Jorda, Radek; Mernyak, Erzsebet 分享 收藏
New Inhibitors of Bcr-Abl Based on 2,6,9-Trisubstituted Purine Scaffold Elicit Cytotoxicity in Chronic Myeloid Leukemia-Derived Cell Lines Sensitive and Resistant to TKIs 基于2,6，9-三取代嘌呤支架的新型bcr-abl抑制剂在对TKIs敏感和耐药的慢性粒细胞白血病衍生细胞系中引起细胞毒性 Delgado, Thalia; Vesela, Denisa; Dostalova, Hana; Krystof, Vladimir; Vojackova, Veronika; Jorda, Radek; Castro, Alejandro; Bertrand, Jeanluc; Rivera, Gildardo; Faundez, Mario; Strnad, Miroslav; Espinosa-Bustos, Christian; Salas, Cristian O. 分享 收藏
Cyclin dependent kinase 4/6 inhibitor palbociclib synergizes with BCL2 inhibitor venetoclax in experimental models of mantle cell lymphoma without RB1 deletion 细胞周期蛋白依赖性激酶4/6抑制剂palbociclib与BCL2抑制剂venetoclax在无RB1缺失的套细胞淋巴瘤实验模型中协同作用 Malarikova, Diana; Jorda, Radek; Kupcova, Kristyna; Senavova, Jana; Dolnikova, Alexandra; Pokorna, Eva; Kazantsev, Dmitry; Nozickova, Kristina; Sovilj, Dana; Bellanger, Celine; Chiron, David; Andera, Ladislav; Krystof, Vladimir; Strnad, Miroslav; Helman, Karel; Klanova, Magdalena; Trneny, Marek; Havranek, Ondrej; Klener, Pavel 分享 收藏
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Inhibition of FLT3-ITD Kinase in Acute Myeloid Leukemia by New Imidazo[1,2-b]pyridazine Derivatives Identified by Scaffold Hopping Brehova, Petra; Reznickova, Eva; Skach, Krystof; Jorda, Radek; Dejmek, Milan; Vojackova, Veronika; Sala, Michal; Kovalova, Marketa; Dracinsky, Martin; Dolnikova, Alexandra; Strmen, Timotej; Kinnertova, Monika; Chalupsky, Karel; Dvorakova, Alexandra; Gucky, Tomas; Kaiserova, Helena Mertlikova; Klener, Pavel; Nencka, Radim; Krystoy, Vladimir 分享 收藏
Characterization of new highly selective pyrazolo[4,3-d]pyrimidine inhibitor of CDK7 Kovalova, Marketa; Havlicek, Libor; Djukic, Stefan; Skerlova, Jana; Perina, Miroslav; Pospisil, Tomas; Reznickova, Eva; Rezacova, Pavlina; Jorda, Radek; Krystof, Vladimir 分享 收藏
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A-ring-fused pyrazoles of dihydrotestosterone targeting prostate cancer cells via the downregulation of the androgen receptor Perina, Miroslav; Kiss, Marton A.; Motyan, Gergo; Szczyrbova, Eva; Elias, Martin; Student Jr, Vladimir; Kurfurstova, Daniela; Kovalova, Marketa; Mada, Lukas; Bouchal, Jan; Frank, Eva; Jorda, Radek 分享 收藏
3,5,7-Substituted Pyrazolo[4,3-d]Pyrimidine Inhibitors of Cyclin-Dependent Kinases and Cyclin K Degraders Jorda, Radek; Havlicek, Libor; Perina, Miroslav; Vojackova, Veronika; Pospisil, Tomas; Djukic, Stefan; Skerlova, Jana; Gruz, Jiri; Renesova, Nicol; Klener, Pavel; Rezacova, Pavlina; Strnad, Miroslav; Krystof, Vladimir 分享 收藏
Design, Synthesis, In Silico Studies and Inhibitory Activity towards Bcr-Abl, BTK and FLT3-ITD of New 2,6,9-Trisubstituted Purine Derivatives as Potential Agents for the Treatment of Leukaemia Bertrand, Jeanluc; Dostalova, Hana; Krystof, Vladimir; Jorda, Radek; Delgado, Thalia; Castro-Alvarez, Alejandro; Mella, Jaime; Cabezas, David; Faundez, Mario; Espinosa-Bustos, Christian; Salas, Cristian O. 分享 收藏
Synthesis and Exploitation of the Biological Profile of Novel Guanidino Xylofuranose Derivatives Fortuna, Andreia; Goncalves-Pereira, Rita; Costa, Paulo J.; Jorda, Radek; Vojackova, Veronika; Gonzalez, Gabriel; Heise, Niels, V; Csuk, Rene; Conceicao Oliveira, M.; Xavier, Nuno M. 分享 收藏
3H-Pyrazolo[4,3-f]quinoline-Based Kinase Inhibitors Inhibit the Proliferation of Acute Myeloid Leukemia Cells In Vivo Dayal, Neetu; Reznickova, Eva; Hernandez, Delmis E.; Perina, Miroslav; Torregrosa-Allen, Sandra; Elzey, Bennett D.; Skerlova, Jana; Ajani, Haresh; Djukic, Stefan; Vojackova, Veronika; Lepsik, Martin; Rezacova, Pavlina; Krystof, Vladimir; Jorda, Radek; Sintim, Herman O. 分享 收藏
Imidazo[1,2-c]pyrimidin-5(6H)-one inhibitors of CDK2: Synthesis, kinase inhibition and co-crystal structure Jansa, Josef; Jorda, Radek; Skerlova, Jana; Pachl, Petr; Perina, Miroslav; Reznickova, Eva; Heger, Tomas; Gucky, Tomas; Rezacova, Pavlina; Lycka, Antonin; Krystof, Vladimir 分享 收藏
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