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Zongjie Gan

Chongqing Medical University

H指数:16

被引数:650

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Design, synthesis, and biological evaluation of the first fibroblast growth factor receptor 4 PROTAC degrader

设计、合成及首个纤维细胞生长因子受体4 PROTAC降解剂的生物学评价

Bioorganic Chemistry

IF4.7

2026-09-010

PRE

Novel Gemini surfactant-polyglutamic acid composite system enhances DNA delivery via a Dual-Engine uptake strategy

新型双亲分子-聚谷氨酸复合体系通过双引擎摄取策略增强DNA递送

International Journal of Pharmaceutics

IF5.2

2026-07-100

PRE

Dual AMPK activation and TXNIP suppression underlie the superior anti-diabetic action of rosiglitazone-metformin co-crystal (RZM): evidence from preclinical models

双AMPK激活和TXNIP抑制构成了罗格列酮-二甲双胍共晶体（RZM）卓越降糖作用的机制基础：来自临床前模型证据

Journal of Drug Targeting

IF3.9

2025-07-170

PRE

A dual-peptides and specific promoter-modified nano gene delivery system for myocardial hypertrophy treatment

一种双肽和特异性启动子修饰的纳米基因递送系统用于心肌肥厚治疗

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

IF8.5

2025-06-010

PRE

Design, synthesis, and biological evaluation of Ponatinib-based N-Phenylpyrimidine-2-amine derivatives as novel fibroblast growth factor receptor 4 (FGFR4) selective inhibitors

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2025-02-010

PRE

Construction and evaluation of liposomal drug delivery system for an ALK/HDACs dual-targeted inhibitor with sustained release and enhanced antitumor effect

DRUG DELIVERY AND TRANSLATIONAL RESEARCH

IF5.5

2024-08-070

PRE

N76-1, a novel CDK7 inhibitor, exhibits potent anti-cancer effects in triple negative breast cancer

N76-1是一种新型的CDK7抑制剂，在三阴性乳腺癌中表现出有效的抗癌作用

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

2023-09-012

OAAI

Design, synthesis and biological evaluation of 2,4-pyrimidinediamine derivatives as ALK and HDACs dual inhibitors for the treatment of ALK addicted cancer

ALK和HDACs双重抑制剂2，4-嘧啶二胺衍生物的设计、合成及生物学评价

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

IF5.4

2022-09-132

OAAI

T-17, a novel cyclin-dependent kinases/histone deacetylases dual inhibitor, induces cancer cells death through cell cycle arrest and apoptosis

DRUG DEVELOPMENT RESEARCH

IF4.2

2022-07-171

PRE

The Biological Fate of a Novel Anticancer Drug Candidate TNBG-5602: Metabolic Profile, Interaction with CYP450, and Pharmacokinetics in Rats

IF4.6

2022-04-182

OAAI

Synthesis and biological evaluation of novel 2,4-dianilinopyrimidine derivatives as potent dual janus kinase 2 and histone deacetylases inhibitors

JOURNAL OF MOLECULAR STRUCTURE

IF4.7

2022-04-014

PRE

Discovery of 2,4-pyrimidinediamine derivatives as potent dual inhibitors of ALK and HDAC

2，4-嘧啶二胺衍生物作为ALK和HDAC的有效双重抑制剂的发现

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2021-11-0120

PREAI

Tetrazanbigen Derivatives as Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) Partial Agonists: Design, Synthesis, Structure-Activity Relationship, and Anticancer Activities

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2021-01-1112

PRE

ctc-[Pt(NH3)2(cinnamate)(valproate)Cl2] is a highly potent and low-toxic triple action anticancer prodrug

DALTON TRANSACTIONS

IF3.3

2021-01-019

PREAI

Detection of B-type natriuretic peptide by establishing a low-cost and replicable fluorescence resonance energy transfer platform

MICROCHIMICA ACTA

IF5.3

2020-05-1517

PREAI

In vitro and in vivo evaluation of liposomes modified with polypeptides and red cell membrane as a novel drug delivery system for myocardium targeting

IF8.1

2020-04-2026

OAAI

A Glimepiride-Metformin Multidrug Crystal: Synthesis, Crystal Structure Analysis, and Physicochemical Properties

IF4.6

2019-10-2120

OAAI

One-Step Regioselective Synthesis of Benzofurans from Phenols and -Haloketones

IF4.6

2019-06-1115

OAAI

Neural mechanisms underlying the deficit of learning and memory by exposure to Di(2-ethylhexyl) phthalate in rats

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

IF6.1

2019-06-0131

PREAI

Eco-Friendly Syntheses of 2-Substituted Benzoxazoles and 2-Substituted Benzothiazoles from 2-Aminophenols, 2-Aminothiophenols and DMF Derivatives in the Presence of Imidazolium Chloride

IF4.6

2019-01-0428

OAAI