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Massimiliano Tognolini

university of parma

32H指数
115论文数
5.3K被引数
收录论文 66
发表时间
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The rare bile acid isoallolithocholic acid (IALCA) is an EphA2 antagonist sparing FXR and TGR5 receptors稀有胆汁酸异石胆酸（IALCA）是EphA2拮抗剂，可避免FXR和TGR5受体。
errBiochemical Pharmacology
IF5.6
err2026-02-13
err0
errOAAI
errAndrea Blesio; Carmine Giorgio; Francesca Romana Ferrari; Stefano Sala; Lisa Flammini; Ilaria Zanotti; Daniela Passeri; Antimo Gioiello; Lorenzo Sarcone; Riccardo Castelli; Kun Karnchanapandh; Federica Vacondio; Lorenzo Tagliazucchi; Laura Scalvini; Marco Mor; Alessio Lodola; Massimiliano Tognolini
err分享
err收藏
Target validation of natural compounds: Perillaldehyde case study天然化合物的靶向验证：薄荷酮案例研究
errInternational Immunopharmacology
IF4.7
err2026-01-10
err0
PREAI
errAndrea Blesio; Carmine Giorgio; Stefano Sala; Andrea Cavazzoni; Ilaria Zanotti; Massimiliano Tognolini
err分享
err收藏
Dual targeting of EphAs and KDR axis hampers VEGF-induced angiogenesis and glioma stem cell replication双靶向EphAs和KDR轴抑制VEGF诱导的血管生成和胶质瘤干细胞复制
errBiochemical Pharmacology
IF5.6
err2025-10-03
err0
errOAAI
errAlfonso Zappia; Francesca Romana Ferrari; Carmine Giorgio; Stefano Sala; Ilaria Zanotti; Simona Parrinello; Melanie P. Clements; Marco Rusnati; Michela Corsini; Andrea Blesio; Riccardo Castelli; Lorenzo Guidetti; Laura Scalvini; Alessio Lodola; Massimiliano Tognolini
err分享
err收藏
Pharmacological characterization and improved PK of new small protein-protein-interaction inhibitors targeting the Eph-ephrin system
errEUROPEAN JOURNAL OF CANCER
IF7.1
err2024-10-01
err0
PREAI
errGiorgio, C.; Ferrari, F. R.; Zappia, A.; Sonvico, F.; Patterlini, V.; Castelli, R.; Lodola, A.; Tognolini, M.
err分享
err收藏
Discovery of a new 1-(phenylsulfonyl)-1H-indole derivative targeting the EphA2 receptor with antiproliferative activity on U251 glioblastoma cell line在U251胶质母细胞瘤细胞系上发现具有抗增殖活性的靶向EphA2受体的新1-(苯磺酰基)-1h-吲哚衍生物
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2024-10-01
err2
errOAAI
errGuidetti, Lorenzo; Castelli, Riccardo; Zappia, Alfonso; Ferrari, Francesca Romana; Giorgio, Carmine; Barocelli, Elisabetta; Pagliaro, Luca; Vento, Federica; Roti, Giovanni; Scalvini, Laura; Vacondio, Federica; Rivara, Silvia; Mor, Marco; Lodola, Alessio; Tognolini, Massimiliano
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Ephrin receptor type-A2 (EphA2) targeting in cancer: a patent review (2018-present)靶向癌症的Ephrin受体type-A2 (EphA2): 专利综述 (2018-pent)
errEXPERT OPINION ON THERAPEUTIC PATENTS
IF4.6
err2024-09-11
err0
PREAI
errTognolini, Massimiliano; Ferrari, Francesca Romana; Zappia, Alfonso; Giorgio, Carmine
err分享
err收藏
Drug discovery: In silico dry data can bypass biological wet data?
errBRITISH JOURNAL OF PHARMACOLOGY
IF7.7
err2023-11-14
err1
errOAAI
errTognolini, Massimiliano; Lodola, Alessio; Giorgio, Carmine
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Molecular Determinants of EphA2 and EphB2 Antagonism Enable the Design of Ligands with Improved Selectivity
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2023-11-01
err2
errOAAI
errGuidetti, Lorenzo; Zappia, Alfonso; Scalvini, Laura; Ferrari, Francesca Romana; Giorgio, Carmine; Castelli, Riccardo; Galvani, Francesca; Vacondio, Federica; Rivara, Silvia; Mor, Marco; Urbinati, Chiara; Rusnati, Marco; Tognolini, Massimiliano; Lodola, Alessio
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A Pharmacological Investigation of Eph-Ephrin Antagonism in Prostate Cancer: UniPR1331 Efficacy EvidenceEph-ephrin拮抗前列腺癌的药理研究: UniPR1331疗效证据
errPHARMACEUTICALS
IF4.8
err2023-10-13
err1
errOAAI
errFestuccia, Claudio; Corrado, Miriam; Rossetti, Alessandra; Castelli, Riccardo; Lodola, Alessio; Gravina, Giovanni Luca; Tognolini, Massimiliano; Giorgio, Carmine
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Pharmacological characterization of second generation FXR agonists as effective EphA2 antagonists: A successful application of target hopping approach
errBIOCHEMICAL PHARMACOLOGY
IF5.6
err2023-03-01
err4
PREAI
errFerrari, Francesca Romana; Giorgio, Carmine; Zappia, Alfonso; Ballabeni, Vigilio; Bertoni, Simona; Barocelli, Elisabetta; Scalvini, Laura; Galvani, Francesca; Mor, Marco; Lodola, Alessio; Tognolini, Massimiliano
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Protein-Protein Interaction Inhibitors Targeting the Eph-Ephrin System with a Focus on Amino Acid Conjugates of Bile Acids靶向eph-ephrin系统的蛋白质-蛋白质相互作用抑制剂，重点是胆汁酸的氨基酸缀合物
errPHARMACEUTICALS
IF4.8
err2022-01-24
err7
errOAAI
errGuidetti, Lorenzo; Castelli, Riccardo; Scalvini, Laura; Ferlenghi, Francesca; Corrado, Miriam; Giorgio, Carmine; Tognolini, Massimiliano; Lodola, Alessio
err分享
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Metabolic Soft Spot and Pharmacokinetics: Functionalization of C-3 Position of an Eph-Ephrin Antagonist Featuring a Bile Acid Core as an Effective Strategy to Obtain Oral Bioavailability in Mice代谢软点和药代动力学: 以胆汁酸核心为特征的eph-ephrin拮抗剂的C-3位置的功能化是获得小鼠口服生物利用度的有效策略
errPHARMACEUTICALS
IF4.8
err2021-12-28
err3
errOAAI
errFerlenghi, Francesca; Giorgio, Carmine; Incerti, Matteo; Guidetti, Lorenzo; Chiodelli, Paola; Rusnati, Marco; Tognolini, Massimiliano; Vacondio, Federica; Mor, Marco; Lodola, Alessio
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Cholenic acid derivative UniPR1331 impairs tumor angiogenesis via blockade of VEGF/VEGFR2 in addition to Eph/ephrin (Aug, 10.1038/s41417-021-00379-5, 2021)胆酸衍生物UniPR1331通过阻断除Eph/ephrin之外的VEGF/VEGFR2来损害肿瘤血管生成 (8月，10.1038/s41417-021-00379-5，2021)
errCANCER GENE THERAPY
IF5
err2021-09-30
err0
errOAAI
errRusnati, Marco; Paiardi, Giulia; Tobia, Chiara; Urbinati, Chiara; Lodola, Alessio; D'Ursi, Pasqualina; Corrado, Miriam; Castelli, Riccardo; Wade, Rebecca C.; Tognolini, Massimiliano; Chiodelli, Paola
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Cholenic acid derivative UniPR1331 impairs tumor angiogenesis via blockade of VEGF/VEGFR2 in addition to Eph/ephrin胆酸衍生物UniPR1331通过阻断Eph/ephrin之外的VEGF/VEGFR2来损害肿瘤血管生成
errCANCER GENE THERAPY
IF5
err2021-08-23
err4
errOAAI
errRusnati, Marco; Paiardi, Giulia; Tobia, Chiara; Urbinati, Chiara; Lodola, Alessio; D'Ursi, Pasqualina; Corrado, Miriam; Castelli, Riccardo; Wade, Rebecca C.; Tognolini, Massimiliano; Chiodelli, Paola
err分享
err收藏
UniPR1331: Small Eph/Ephrin Antagonist Beneficial in Intestinal Inflammation by Interfering with Type-B SignalingUniPR1331: 小Eph/Ephrin拮抗剂通过干扰b型信号有益于肠道炎症
errPHARMACEUTICALS
IF4.8
err2021-05-24
err2
errOAAI
errGiorgio, Carmine; Allodi, Marika; Palese, Simone; Grandi, Andrea; Tognolini, Massimiliano; Castelli, Riccardo; Lodola, Alessio; Flammini, Lisa; Cantoni, Anna Maria; Barocelli, Elisabetta; Bertoni, Simona
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Evaluation of the Anti-Tumor Activity of Small Molecules Targeting Eph/Ephrins in APC min/J Mice
errPHARMACEUTICALS
IF4.8
err2020-04-16
err1
errOAAI
errCorrado, Miriam; Giorgio, Carmine; Barocelli, Elisabetta; Vittucci Marzetti, Giuseppe; Cantoni, Anna Maria; Di Lecce, Rosanna; Incerti, Matteo; Castelli, Riccardo; Lodola, Alessio; Tognolini, Massimiliano
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Optimization of EphA2 antagonists based on a lithocholic acid core led to the identification of UniPR505, a new 3α-carbamoyloxy derivative with antiangiogenetic properties基于石胆酸核心的EphA2拮抗剂的优化导致了UniPR505的鉴定，UniPR505是一种具有抗血管生成特性的新型3 α-氨基甲酰氧基衍生物
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2020-03-01
err6
PREAI
errIncerti, Matteo; Russo, Simonetta; Corrado, Miriam; Giorgio, Carmine; Ballabeni, Vigilio; Chiodelli, Paola; Rusnati, Marco; Scalvini, Laura; Callegari, Donatella; Castelli, Riccardo; Vacondio, Federica; Ferlenghi, Francesca; Tognolini, Massimiliano; Lodola, Alessio
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Drug-gut microbiota metabolic interactions: the case of UniPR1331, selective antagonist of the Eph-ephrin system, in mice
errJOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
IF3.1
err2020-02-01
err8
PREAI
errFerlenghi, Francesca; Castelli, Riccardo; Scalvini, Laura; Giorgio, Carmine; Corrado, Miriam; Tognolini, Massimiliano; Mor, Marco; Lodola, Alessio; Vacondio, Federica
err分享
err收藏
Enhanced photosensitizing properties of protein bound curcumin
errLIFE SCIENCES
IF5.1
err2019-09-01
err24
PREAI
errCozzolino, Marco; Delcanale, Pietro; Montalie, Chiara; Tognolini, Massimiliano; Giorgio, Carmine; Corrado, Miriam; Cavanna, Luigi; Bianchini, Paolo; Diaspro, Alberto; Abbruzzetti, Stefania; Viappiani, Cristiano
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Hypericin-Apomyoglobin: An Enhanced Photosensitizer Complex for the Treatment of Tumor Cells
errBIOMACROMOLECULES
IF5.4
err2019-04-17
err25
PREAI
errBianchini, Paolo; Cozzolino, Marco; Oneto, Michele; Pesce, Luca; Pennacchietti, Francesca; Tognolini, Massimiliano; Giorgio, Carmine; Nonell, Santi; Cavanna, Luigi; Delcanale, Pietro; Abbruzzetti, Stefania; Diaspro, Alberto; Viappiani, Cristiano
err分享
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研究方向

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合作学者
合作期刊
A
Alan Crozier
H 指数: 106 · 论文数: 455
L
Lawrence F. Brass
H 指数: 78 · 论文数: 254
D
Daniele Del Rio
H 指数: 78 · 论文数: 449
L
Lorenzo Piemonti
H 指数: 78 · 论文数: 531
E
Elena B. Pasquale
H 指数: 76 · 论文数: 324
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