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J

Jacobus Burggraaf

Centre for Human Drug Research
H指数:54
被引数:9,945

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Early development of LRX712, preclinical chondroanabolic findings and results from a randomized first-in-human study

LRX712的早期开发、非临床软骨再生发现及来自一项随机首次人体研究的成果

ARTHRITIS RESEARCH & THERAPY
IF4.6
2026-09-180
OAAI
Anouk C. Meijs; Josephina P.M. Vrouwe; Franziska Saxer; Ina Kramer; Angelika Meyer; Jimmy Elliott; Christian Kolter; Serge Summermatter; Gerard Bruin; Azeddine Elhajouji; Frederik E. Stuurman; Jacobus Burggraaf; Andreas Fisch; Bernd Riebesehl; Nicole Gerwin; Sabine Guth-Gundel; Kristen Johnson; Pia Kuss; Stephan Utzinger; David Sanchez-Ramos; Laura Coleman; Celeste Scotti; Karin Meiser; Michaela Kneissel; Ronenn Roubenoff; Naomi B. Klarenbeek; Matthias Schieker
Rapid Ex Vivo Visualization of Laryngeal Tumors Using a Sprayable pH-Activatable Fluorophore

使用喷雾式pH激活荧光探针快速体外可视化喉肿瘤

Molecular Diagnosis & Therapy
IF4.4
2026-09-110
OAAI
Daan G. J. Linders; Sebastiaan W. R. Dalmeijer; Bo E. Zweedijk; Hamed Abbasi; Danielle Boldewijn; Sjors A. Koppes; Bernd Kremer; Jacobus Burggraaf; Denise E. Hilling; Joost R. van der Vorst; Jinhui Ser; Satoshi Kashiwagi; Maged Henary; Jeroen C. Jansen; Alexander L. Vahrmeijer; Hak Soo Choi; Stijn Keereweer
Early immune responses to intradermal lipopolysaccharide in healthy volunteers: prednisolone’s impact on TLR4-mediated inflammation

健康志愿者皮内脂多糖的早期免疫反应：泼尼松龙对TLR4介导炎症的影响

Frontiers in Immunology
IF5.9
2026-05-200
OAAI
TP Thomas P. Buters; DT Digna T. de Bruin; PW Pieter W. Hameeteman; WT Wouter ten Voorde; HW Hendrika W. Grievink; MO Michelle Osse; ML Marieke L. de Kam; JD Jeffrey Damman; TP Thierry P. P. van den Bosch; EN Elsa Neubert; RR Robert Rissmann; JB Jacobus Burggraaf; NK Naomi Klarenbeek; MA Manon A. A. Jansen; MM Matthijs Moerland
Clinical Validation of Imaging Biomarkers in Mycosis Fungoides

皮肤T细胞淋巴瘤影像生物标志物的临床验证

Experimental Dermatology
IF3.1
2026-03-110
OAAI
Selinde S. Wind; Elise S. M. Beljaards; Rianne Rijneveld; Lisa Bruijnincx; Tessa Niemeyer-van der Kolk; Manon A. A. Jansen; Yalcin Yavuz; Marieke de Kam; Jacobus Burggraaf; Naomi Klarenbeek; Jacobus Bosch; Koen D. Quint; Maarten H. Vermeer; Robert Rissmann; Next-Generation ImmunoDermatology Consortium (NGID)
Neoantigen immune responses in healthy volunteers: insights from multiple integrated keyhole limpet hemocyanin challenge studies on repeated immunization and response covariates

新生抗原免疫反应在健康志愿者中的研究：来自多次整合钥孔血蓝蛋白挑战研究对重复免疫接种和反应协变量的见解

Frontiers in Pharmacology
IF4.8
2026-01-020
OAAI
Micha N. Ronner†; Marieke L. De Kam; Silke Van Reeuwijk; Jacobus Burggraaf†; Manon A. A. Jansen†; Matthijs Moerland
Correction: Preclinical evaluation of glycan-targeting monoclonal antibodies for bimodal near-infrared fluorescence and photoacoustic imaging of gastrointestinal cancers

更正：对靶向糖类的单克隆抗体进行临床前评估，用于胃肠癌的双模态近红外荧光和光声成像。

EJNMMI Research
IF3
2025-09-020
OAAI
Ruben D. Houvast; Vincent Q. Sier; Maurice van Duijvenvoorde; Victor M. Baart; Timo Schomann; JiaXin Chua; Mireille Vankemmelbeke; Lindy G. Durrant; Daniëlle Krijgsman; Pieter de Heer; Gert-Jan Hassing; J. Sven D. Mieog; A. Stijn L. P. Crobach; Jacobus Burggraaf; Peter J. K. Kuppen; Alexander L. Vahrmeijer; Cornelis F. M. Sier
Preoperative chemotherapy reduces the accumulation of indocyanine green around colorectal liver metastases for use in fluorescence-guided surgery

术前化疗降低了吲哚菁绿在结直肠癌肝转移灶周围的蓄积，以用于荧光引导手术

SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
IF2.7
2025-09-010
OAAI
Bijlstra, Okker D.; Dijkhuis, Tom H.; Achterberg, Friso B.; Broersen, Alexander; Dijkstra, Jouke; Warmerdam, Mats I.; Henrar, Rutger B.; Burggraaf, Jacobus; Crobach, A. Stijn L. P.; Swijnenburg, Rutger-Jan; Kuppen, Peter J. K.; Vahrmeijer, Alexander L.; Mieog, J. Sven D.
Adverse immunostimulation in early phase clinical trials: Key findings and recommendations based on the investigator's clinical experience

早期临床试验中的不良免疫刺激：基于研究者临床经验的关键发现和建议

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
IF3
2025-09-010
OAAI
van den Noort, Juliette A.; van Ruissen, Marella C. E.; Smidt, Lisanne C. A.; Klarenbeek, Naomi B.; Kremer, Philip H. K.; Jansen, Manon A. A.; Burggraaf, Jacobus; van Gerven, Joop M. A.; Moerland, Matthijs
Profiling a Neo-Antigen-Driven Immune Response in Healthy Volunteers: A Randomized, Double-Blind, Placebo-Controlled Study of the KLH Challenge Model

在健康志愿者中分析新抗原驱动的免疫反应：KLH挑战模型的一项随机、双盲、安慰剂对照研究

Clinical Pharmacology & Therapeutics
IF5.5
2025-07-220
OAAI
Micha N. Ronner; Hendrika W. Grievink; Mahdi Saghari; Michelle Osse; Thierry P.P. van den Bosch; Jeffrey Damman; Marieke L. de Kam; Jacobus Burggraaf; Naomi B. Klarenbeek; Manon A. A. Jansen; Matthijs Moerland
Long-term Local Control Following CEA-targeted Fluorescence-guided Surgery in Patients With Locally Advanced and Recurrent Rectal Cancer

CEA靶向荧光引导手术在局部晚期和复发性直肠癌患者中的长期局部控制

Molecular Imaging and Biology
IF2.5
2025-06-050
OA
Mats I. Warmerdam; Davy M. J. Creemers; Miranda Kusters; Koen C. M. J. Peeters; Fabian A. Holman; J. Sven D. Mieog; Francoise Cailler; Pim J. W. A. Burger; Jacobus Burggraaf; Harm J. T. Rutten; Cornelis Verhoef; Alexander L. Vahrmeijer; Denise E. Hilling
Effects of Neoadjuvant Therapy on Tumour Target Expression of Oesophageal Cancer Tissue for NIR Fluorescence Imaging
MOLECULAR IMAGING AND BIOLOGY
IF2.5
2024-11-190
PRE
Galema, Hidde A.; Neijenhuis, Lisanne K. A.; Lauwerends, Lorraine J.; Dekker-Ensink, N. Geeske; Verhoef, Cornelis; Vahrmeijer, Alexander L.; Bhairosingh, Shadhvi S.; Kuppen, Peter J. K.; Rogalla, Stephan; Burggraaf, Jacobus; Lagarde, Sjoerd M.; Wijnhoven, Bas P. L.; Hutteman, Merlijn; Doukas, Michail; Keereweer, Stijn; Hilling, Denise E.
Ex vivo fluorescence-guided resection margin assessment in breast cancer surgery using a topically applied, cathepsin-activatable imaging agent

使用局部应用的组织蛋白酶可激活的成像剂在乳腺癌手术中进行离体荧光引导的切除边缘评估

PHARMACOLOGICAL RESEARCH
IF10.5
2024-11-010
OAAI
Linders, Daan G. J.; Bijlstra, Okker D.; Walker, Ethan; March, Taryn L.; Pool, Martin; Valentijn, A. Rob P. M.; Dijkhuis, Tom H.; Woltering, Jikke N.; Pijl, Floor R.; Noordam, Gilbert; van den Burg, Davey; van der Sijp, Joost R. M.; Guicherit, Onno R.; Marinelli, Andreas W. K. S.; Burggraaf, Jacobus; Rissmann, Robert; Bogyo, Matthew; Hilling, Denise E.; Kuppen, Peter J. K.; Straight, Brian; Straver, Marieke E.; Hazelbag, Hans Marten; Basilion, James P.; Vahrmeijer, Alexander L.
Indocyanine green near-infrared fluorescence bowel perfusion assessment to prevent anastomotic leakage in minimally invasive colorectal surgery (AVOID) : a multicentre, randomised, controlled, phase 3 trial
LANCET GASTROENTEROLOGY & HEPATOLOGY
IF38.6
2024-10-011
PRE
Faber, Robin A.; Meijer, Ruben P. J.; Droogh, Daphne H. M.; Jongbloed, Jasmijn J.; Bijlstra, Okker D.; Boersma, Fran; Braak, Jeffrey P. B. M.; Kranenbarg, Elma Meershoek-Klein; Putter, Hein; Holman, Fabian A.; Mieog, J. Sven D.; Neijenhuis, Peter A.; van Staveren, Esther; Bloemen, Johanne G.; Burger, Jacobus W. A.; Aukema, Tjeerd S.; Brouwers, Mark A. M.; Marinelli, Andreas W. K. S.; Westerterp, Marinke; Doornebosch, Pascal G.; van der Weijde, Annelies; Bosscha, Koop; Handgraaf, Henricus J. M.; Consten, Esther C. J.; Sikkenk, Daan J.; Burggraaf, Jacobus; Keereweer, Stijn; van der Vorst, Joost R.; Hutteman, Merlijn; Peeters, Koen C. M. J.; Vahrmeijer, Alexander L.; Hilling, Denise E.
Lesional skin of seborrheic dermatitis patients is characterized by skin barrier dysfunction and correlating alterations in the stratum corneum ceramide composition
EXPERIMENTAL DERMATOLOGY
IF3.1
2023-11-1611
OAAI
Rousel, Jannik; Nadaban, Andreea; Saghari, Mahdi; Pagan, Lisa; Zhuparris, Ahnjili; Theelen, Bart; Gambrah, Tom; van Der Wall, Hein E. C.; Vreeken, Rob J.; Feiss, Gary L.; Niemeyer-van der Kolk, Tessa; Burggraaf, Jacobus; van Doorn, Martijn B. A.; Bouwstra, Joke A.; Rissmann, Robert

研究方向

暂未获取到该数据
A
Adam F. Cohen
H 指数:54论文数:435被引数:1.1万
M
Matthijs Moerland
H 指数:28论文数:148被引数:2,625
R
Robert Rißmann
H 指数:28论文数:238被引数:2,236
A
Alexander L. Vahrmeijer
H 指数:71论文数:556被引数:1.9万
R
Rik C. Schoemaker
H 指数:51论文数:252被引数:7,879
M
Marieke L. de Kam
H 指数:29论文数:114被引数:2,919
I
Ingrid M. C. Kamerling
H 指数:16论文数:68被引数:1,256
G
Gary Feiss
H 指数:17论文数:61被引数:722
T
Tessa Niemeyer‐van der Kolk
H 指数:11论文数:48被引数:431
D
Denise E. Hilling
H 指数:26论文数:113被引数:3,051