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Identification and Investigation of Novel Binding Fragments in the Fatty Acid Binding Protein 6 (FABP6)JOURNAL OF MEDICINAL CHEMISTRYIF6.82016-08-1814PREAI
Multiparameter Lead Optimization to Give an Oral Checkpoint Kinase 1 (CHK1) Inhibitor Clinical Candidate: (R)-5-((4-((Morpholin-2-ylmethyl)amino)-5-(trifluoromethyl)pyridin-2-yl)amino)pyrazine-2-carbonitrile (CCT245737)JOURNAL OF MEDICINAL CHEMISTRYIF6.82016-05-2330OAAI
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Lead Optimization toward Proof-of-Concept Tools for Huntington's Disease within a 4-(1H-Pyrazol-4-yl)pyrimidine Class of Pan-JNK InhibitorsJOURNAL OF MEDICINAL CHEMISTRYIF6.82015-03-1936PREAI
Design, Synthesis, and Biological Evaluation of Potent and Selective Class IIa Histone Deacetylase (HDAC) Inhibitors as a Potential Therapy for Huntington's DiseaseJOURNAL OF MEDICINAL CHEMISTRYIF6.82013-12-05134PREAI
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