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R

Ronald L. Wange

food and drug administration
H指数:37
被引数:5,474

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Beyond NAMs versus animal models: Context of use as the governing framework for integrated nonclinical strategies in drug development

超越NAMs与动物模型：使用情境作为药物开发中综合非临床策略的指导框架

Regulatory Toxicology and Pharmacology
IF3.5
2026-09-010
PRE
Gaburro, Stefano; Berridge, Brian; Kelley, Nicholas W.; von Keutz, Eckhard; Ferrer, Marc; Roper, Clive; Fossler, Michael J.; Bajramovic, Jeffrey J.; Valentin, Jean-Pierre; McGovern, Timothy; Bourcier, Todd; Wange, Ronald L.; Snyder, Kevin; Phelan, Michael A.; Oliphant, Jessica H.; Leishman, Derek J.; Proctor, William R.; Maguire, Sean; Dama, Paola; Nag, Madhu; Williams, Dominic P.; Roth, Adrian; Kanda, Yasunari; Baran, Szczepan
Safety considerations for cereblon-recruiting targeted protein degraders

Cerebon招募靶向蛋白降解剂的安全注意事项

Nature Reviews Drug Discovery
IF101.8
2026-04-200
PRE
Helen Garside; Amy Aslamkhan; Danette L. Daniels; Kaushik Datta; Mikael Egebjerg; Renee R. Hukkanen; Lyn H. Jones; Natalie Ketter; Tejas S. Lahoti; Lise I. Loberg; Davorka Messmer; Raegan O’Lone; Timothy Pastoor; Mira Pavkovic; Lucilia Pereira Mouriès; Zoran Rankovic; Aishwarya Rengarajan; Neil Vargesson; Axel Vicart; Ronald L. Wange; Gina Yanochko-Hoffman; Ruth Roberts; James Sidaway
Corrigendum to “Hypothesis-driven approach to developmental toxicity assessment: Using mechanistic information to inform testing” [Reprod. Toxicol. 140 (2026) 109119]

勘误：题为“Hypothesis-driven approach to developmental toxicity assessment: Using mechanistic information to inform testing”的文章 [Reprod. Toxicol. 140 (2026) 109119]

Reproductive Toxicology
IF2.8
2025-12-260
OAAI
George Daston; Matthew Burbank; Florian Gautier; Barbara F. Hales; Amer Jamalpoor; Yasunari Kanda; Susan Makris; Aldert H. Piersma; Nicola Powles-Glover; Sonya Sobrian; Vicki Sutherland; Steven Van Cruchten; Ronald L. Wange; Connie L. Chen
Minimizing Use of Nonhuman Primates to Inform Risk to Fertility and of Adverse Pregnancy Outcomes with Pharmaceuticals

最小化非人灵长类动物的使用，以评估药物对生育力和不良妊娠结局的风险。

Regulatory Toxicology and Pharmacology
IF3.5
2025-10-240
PRE
Christopher J. Bowman; Ann Baker; Diann L. Blanset; Kimberly C. Brannen; Gary J. Chellman; Brian Enright; Wendy Halpern; Bethany R. Hannas; Kazushige Maki; Fumito Mikashima; Shermaine Mitchell-Ryan; Eve Mylchreest; Manjunatha K. Nanjappa; Helen Prior; Puck Roos; Dinesh Stanislaus; Angela R. Stermer; Jane Stewart; Katie Turner; Steven van Cruchten; Peter J.K. van Meer; Justin D. Vidal; Ronald L. Wange; Connie Chen; Peter Theunissen
New approach methodologies for assessing developmental toxicity of pharmaceuticals: Case Examples and Future Directions

新方法学在药物发育毒性评估中的应用：案例示例与未来方向

Reproductive Toxicology
IF2.8
2025-08-280
OAAI
Nicola Powles-Glover; Allen R. Kaczor; Steven Van Cruchten; Christopher J. Bowman; Kimberly C. Brannen; Claudia Demarta-Gatsi; Isabelle LeConte; Amer Jamalpoor; Fumito Mikashima; Shermaine Mitchell-Ryan; Dinesh Stanislaus; Peter Theunissen; Belen Tornesi; Ronald L. Wange; Connie L. Chen
Developmental and Reproductive Toxicity Testing Strategies for Oligonucleotides: A Workshop Proceedings

寡核苷酸发育与生殖毒性测试策略：研讨会论文集

nucleic acid therapeutics
IF4.7
2025-06-050
PRE
Bethany R. Hannas; Sara M. Bender; Eileen Blasi; Christopher J. Bowman; Joy A. Cavagnaro; Connie L. Chen; Pragati S. Coder; Britt Duijndam; Alan Hoberman; Tae-Won Kim; Isabelle Leconte; Kazushige Maki; Mineo Matsumoto; Fumito Mikashima; Dinah L. Misner; Lutz Mueller; Nicola Powles-Glover; Stephanie Rayhon; Camelia Saffarini; Christine Siezen; Jennifer Sisler; Ronald L. Wange; Tacey White; Michael V. Templin
IVIVE: Facilitating the Use of In Vitro Toxicity Data in Risk Assessment and Decision Making
TOXICS
IF4.1
2022-05-0165
OAAI
Chang, Xiaoqing; Tan, Yu-Mei; Allen, David G.; Bell, Shannon; Brown, Paul C.; Browning, Lauren; Ceger, Patricia; Gearhart, Jeffery; Hakkinen, Pertti J.; Kabadi, Shruti V.; Kleinstreuer, Nicole C.; Lumen, Annie; Matheson, Joanna; Paini, Alicia; Pangburn, Heather A.; Petersen, Elijah J.; Reinke, Emily N.; Ribeiro, Alexandre J. S.; Sipes, Nisha; Sweeney, Lisa M.; Wambaugh, John F.; Wange, Ronald; Wetmore, Barbara A.; Mumtaz, Moiz
3D cell culture models: Drug pharmacokinetics, safety assessment, and regulatory consideration
CTS-CLINICAL AND TRANSLATIONAL SCIENCE
IF2.8
2021-06-16120
OAAI
Wang, Hongbing; Brown, Paul C.; Chow, Edwin C. Y.; Ewart, Lorna; Ferguson, Stephen S.; Fitzpatrick, Suzanne; Freedman, Benjamin S.; Guo, Grace L.; Hedrich, William; Heyward, Scott; Hickman, James; Isoherranen, Nina; Li, Albert P.; Liu, Qi; Mumenthaler, Shannon M.; Polli, James; Proctor, William R.; Ribeiro, Alexandre; Wang, Jian-Ying; Wange, Ronald L.; Huang, Shiew-Mei

研究方向

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M
Maria‐Cristina Seminario
H 指数:11论文数:15被引数:583
L
Lawrence E. Samelson
H 指数:88论文数:239被引数:2.8万
P
Paul C. Brown
H 指数:17论文数:58被引数:991
C
Christopher Bowman
H 指数:38论文数:204被引数:6,303
S
Steven Van Cruchten
H 指数:28论文数:173被引数:3,327
Y
Yasunari Kanda
H 指数:38论文数:298被引数:4,847
T
Todd Bourcier
H 指数:12论文数:46被引数:2,969
P
Patricia Precht
H 指数:20论文数:43被引数:1,148
C
Connie L. Chen
H 指数:15论文数:43被引数:830
S
Shermaine Mitchell-Ryan
H 指数:9论文数:22被引数:351