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R

Raimo K. Tuominen

university of helsinki

H指数:31

被引数:4,168

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Expanding the Paradigm of Structure-Based Drug Design: Molecular Dynamics Simulations Support the Development of New Pyridine-Based Protein Kinase C-Targeted Agonists

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2023-04-032

OAAI

Protein Kinase A-Mediated Effects of Protein Kinase C Partial Agonist 5-(Hydroxymethyl)Isophthalate 1a3 in Colorectal Cancer

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2022-01-013

OAAI

Neuroprotective Potential of a Small Molecule RET Agonist in Cultured Dopamine Neurons and Hemiparkinsonian Rats

JOURNAL OF PARKINSONS DISEASE

IF5

2021-08-029

OAAI

Rigorous Computational Study Reveals What Docking Overlooks: Double Trouble from Membrane Association in Protein Kinase C Modulators

严格的计算研究揭示了对接所忽略的: 蛋白激酶C调节剂中膜缔合的双重麻烦

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2020-09-115

PREAI

Engineered antibody-functionalized porous silicon nanoparticles for therapeutic targeting of pro-survival pathway in endogenous neuroblasts after stroke

IF12.9

2020-01-0124

OAAI

Missing Selectivity of Targeted 4β-Phorbol Prodrugs Expected to be Potential Chemotherapeutics

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2019-12-237

OAAI

Glial cell line-derived neurotrophic factor receptor REarranged during transfection agonist supports dopamine neurons in Vitro and enhances dopamine release In Vivo

转染过程中重排的胶质细胞源性神经营养因子受体激动剂在体外支持多巴胺神经元并在体内增强多巴胺释放

MOVEMENT DISORDERS

IF7.6

2019-12-1627

OAAI

MANF Promotes Differentiation and Migration of Neural Progenitor Cells with Potential Neural Regenerative Effects in Stroke

MOLECULAR THERAPY

IF12

2018-01-0174

OAAI

Depolarizing -aminobutyric acid contributes to glutamatergic network rewiring in epilepsy

ANNALS OF NEUROLOGY

IF7.7

2017-02-2351

OAAI

Methadone's effect on nAChRs-a link between methadone use and smoking?

BIOCHEMICAL PHARMACOLOGY

IF5.6

2015-10-0115

PREAI

C1 domain-targeted isophthalates as protein kinase C modulators: structure-based design, structure-activity relationships and biological activities

BIOCHEMICAL SOCIETY TRANSACTIONS

IF4.3

2014-11-177

OAAI

Evidence for a role of MRCK in mediating He La cell elongation induced by the Cl domain ligand HMI-1a3

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

IF4.7

2014-05-0110

PREAI

The C1 domain-targeted isophthalate derivative HMI-1b11 promotes neurite outgrowth and GAP-43 expression through PKCα activation in SH-SY5Y cells

PHARMACOLOGICAL RESEARCH

IF10.5

2013-07-0128

PRE

Nicotine-morphine interactions at α4β2, α7 and α3* nicotinic acetylcholine receptors

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

2013-02-0123

PREAI

High correlation between in vivo [123I]β-CIT SPECT/CT imaging and post-mortem immunohistochemical findings in the evaluation of lesions induced by 6-OHDA in rats

EJNMMI RESEARCH

IF3

2013-01-0122

OAAI

CDNF Protects the Nigrostriatal Dopamine System and Promotes Recovery After MPTP Treatment in Mice

CELL TRANSPLANTATION

IF3.2

2012-06-01117

OA

Nicotine-opioid interactions: in vitro and in vivo studies

EUROPEAN NEUROPSYCHOPHARMACOLOGY

IF6.7

2011-04-010

PREAI

Reinforcing effects of cocaine in COMT knockout mice

EUROPEAN NEUROPSYCHOPHARMACOLOGY

IF6.7

2011-03-010

PREAI

The development of activating and inhibiting camelid VHH domains against human protein kinase C epsilon

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

IF4.7

2011-03-0116

PREAI

HIV-1 Tat-peptide inhibits protein kinase C and protein kinase A through substrate competition

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

IF4.7

2010-08-0127

PREAI