Frédéric Y. Bois - Publications, H-index & Citations

Frédéric Y. Bois

Certara France

53H指数

366论文数

9.6K被引数

收录论文 103

发表时间

Virtual Bioequivalence Assessment of Long-acting Injectable Suspensions Using PBPK Modeling: Part 1. Impact of particle Size on Formulation Variability 基于PBPK建模的长效注射用混悬剂的虚拟生物等效性评估：第1部分。粒径对制剂变异性影响

The AAPS Journal

IF0

2026-04-03

PREAI

Natalie M. Morris; Alexandre Djehizian; Naresh Mittapelly; Krishna Chaitanya Telaprolu; Bryan W. Holland; Kevin McNally; Sebastian Polak; Masoud Jamei; Khondoker Alam; Eleftheria Tsakalozou; Mark Donnelly; Kairui Feng; Frederic Y. Bois

Virtual Bioequivalence Assessment of Long-Acting Injectable Suspensions Using PBPK Modeling: Part 2. Type I Error and Safe Space Analyses 基于PBPK建模的长效注射用混悬液虚拟生物等效性评估：第2部分。Ⅰ型错误和安全空间分析

The AAPS Journal

IF0

2026-04-03

PREAI

Natalie M. Morris; Masoud Jamei; Khondoker Alam; Eleftheria Tsakalozou; Mark Donnelly; Kairui Feng; Frederic Y. Bois

Assessing Hepatic Impairment with Biomarker-informed Physiologically-based Pharmacokinetic Modelling (BI-PBPK): Strengths and Limitations of the Endogenous Biomarker Coproporphyrin-I 评估肝脏损伤与生物标志物指导的生理学基础药代动力学模型（BI-PBPK）：内源性生物标志物粪卟啉-I的优缺点

Drug Metabolism and Disposition

IF4

2025-11-28

PREAI

Jakub Witkowski; Sibylle Neuhoff; Mailys De Sousa Mendes; Frederic Y. Bois; Matthew D. Harwood

Corrigendum to “radiation dosimetry of the 18 kDa translocator protein ligand [18F]PBR111 in humans” [nuclear medicine and biology, 144–145 (2025); 109,011]勘误：“18 kDa translocator protein ligand [18F]PBR111 in humans”的辐射剂量测定 [核医学与生物学, 144–145 (2025); 109,011]

Nuclear Medicine and Biology

IF3

2025-06-24

PREAI

Benjamin B. Tournier; Zahra Mansouri; Yazdan Salimi; Kelly Ceyzériat; Gregory Mathoux; Hélène Richard-Lepouriel; Daniele Zullino; Frédéric Bois; Habib Zaidi; Valentina Garibotto; Stergios Tsartsalis; Philippe Millet

Identifying human toxicodynamic variability: A systematic evidence map of the current knowledge 识别人类毒动学变异性：当前知识的系统证据图谱

REGULATORY TOXICOLOGY AND PHARMACOLOGY

IF3.5

2025-06-06

PREAI

Annika Boye Petersen; Lea Bredsdorff; Natasha Tahir; Marije Niemeijer; George E.N. Kass; Aiste Vitkauskaite; Matthijs Moerland; Frederic Y. Bois; Nadia Quignot; Bob van de Water; Susanne Hougaard Bennekou

Radiation dosimetry of the 18 kDa translocator protein ligand [18F]PBR111 in humans

NUCLEAR MEDICINE AND BIOLOGY

IF3

2025-01-01

PREAI

Tournier, Benjamin B.; Mansouri, Zahra; Salimi, Yazdan; Ceyzeriat, Kelly; Mathoux, Gregory; Richard-Lepouriel, Helene; Zullino, Daniele; Bois, Frederic; Zaidi, Habib; Garibotto, Valentina; Tsartsalis, Stergios; Millet, Philippe

Applications of the Cholesterol Metabolite, 4β-Hydroxycholesterol, as a Sensitive Endogenous Biomarker for Hepatic CYP3A Activity Evaluated within a PBPK Framework

PHARMACEUTICS

IF5.5

2024-09-30

OAAI

Karkhanis, Aneesh V.; Harwood, Matthew D.; Stader, Felix; Bois, Frederic Y.; Neuhoff, Sibylle

A guide to developing population files for physiologically-based pharmacokinetic modeling in the Simcyp Simulator

CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY

IF3

2024-07-18

OAAI

Curry, Liam; Alrubia, Sarah; Bois, Frederic Y.; Clayton, Ruth; El-Khateeb, Eman; Johnson, Trevor N.; Faisal, Muhammad; Neuhoff, Sibylle; Wragg, Kris; Rostami-Hodjegan, Amin

Mapping Interindividual Variability of Toxicodynamics Using High-Throughput Transcriptomics and Primary Human Hepatocytes from Fifty Donors

ENVIRONMENTAL HEALTH PERSPECTIVES

IF9.8

2024-03-01

OAAI

Niemeijer, Marije; Wiecek, Witold; Fu, Shuai; Huppelschoten, Suzanna; Bouwman, Peter; Baze, Audrey; Parmentier, Celine; Richert, Lysiane; Paules, Richard S.; Bois, Frederic Y.; van de Water, Bob

Understanding Discordance between In Vitro Dissolution, Local Gut and Systemic Bioequivalence of Budesonide in Healthy and Crohn's Disease Patients through PBPK Modeling

PHARMACEUTICS

IF5.5

2023-08-30

OAAI

Han, Chunyan; Sun, Tiancheng; Chirumamilla, Siri Kalyan; Bois, Frederic Y.; Xu, Mandy; Rostami-Hodjegan, Amin

Population PBPK modeling using parametric and nonparametric methods of the Simcyp Simulator, and Bayesian samplers 使用Simcyp模拟器的参数和非参数方法以及贝叶斯采样器对人口PBPK进行建模

CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY

IF3

2022-04-22

OAAI

Wedagedera, Janak R.; Afuape, Anthonia; Chirumamilla, Siri Kalyan; Momiji, Hiroshi; Leary, Robert; Dunlavey, Mike; Matthews, Richard; Abduljalil, Khaled; Jamei, Masoud; Bois, Frederic Y.

Integrate mechanistic evidence from new approach methodologies (NAMs) into a read-across assessment to characterise trends in shared mode of action

TOXICOLOGY IN VITRO

IF2.7

2022-03-01

OAAI

Escher, Sylvia E.; Aguayo-Orozco, Alejandro; Benfenati, Emilio; Bitsch, Annette; Braunbeck, Thomas; Brotzmann, Katharina; Bois, Frederic; van der Burg, Bart; Castel, Jose; Exner, Thomas; Gadaleta, Domenico; Gardner, Iain; Goldmann, Daria; Hatley, Oliver; Golbamaki, Nazanin; Graepel, Rabea; Jennings, Paul; Limonciel, Alice; Long, Anthony; Maclennan, Richard; Mombelli, Enrico; Norinder, Ulf; Jain, Sankalp; Capinha, Liliana Santos; Taboureau, Olivier T.; Tolosa, Laia; Vrijenhoek, Nanette G.; Van Vugt-Lussenburg, Barbara M. A.; Walker, Paul; van de Water, Bob; Wehr, Matthias; White, Andrew; Zdrazil, Barbara; Fisher, Ciaran

Opening a debate on open-source modeling tools: Pouring fuel on fire versus extinguishing the flare of a healthy debate

CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY

IF3

2021-05-01

OAAI

Rostami-Hodjegan, Amin; Bois, Frederic Y.

Multistate models of developmental toxicity: Application to valproic acid-induced malformations in the zebrafish embryo

TOXICOLOGY AND APPLIED PHARMACOLOGY

IF3.4

2021-03-01

OAAI

Simeon, Segolene; Beaudouin, Remy; Brotzmann, Katharina; Braunbeck, Thomas; Bois, Frederic Y.

Sentinel Coronavirus environmental monitoring can contribute to detecting asymptomatic SARS-CoV-2 virus spreaders and can verify effectiveness of workplace COVID-19 controls

MICROBIAL RISK ANALYSIS

IF4

2020-12-01

OAAI

Marshall, Douglas L.; Bois, Frederic; Jensen, Soren K. S.; Linde, Svend A.; Higby, Richard; Remy-McCort, Yvoine; Murray, Sean; Dieckelman, Bryan; Sudradjat, Fitri; Martin, Gilles G.

Development of a generic zebrafish embryo PBPK model and application to the developmental toxicity assessment of valproic acid analogs (vol 93, pg 219, 2020)

REPRODUCTIVE TOXICOLOGY

IF2.8

2020-12-01

PREAI

Simeon, Segolene; Brotzmann, Katharina; Fisher, Ciaran; Gardner, Iain; Silvester, Steve; Maclennan, Richard; Walker, Paul; Braunbeck, Thomas; Bois, Frederic Y.

A generic PBTK model implemented in the MCRA platform: Predictive performance and uses in risk assessment of chemicals

FOOD AND CHEMICAL TOXICOLOGY

IF3.5

2020-08-01

OAAI

Tebby, Cleo; van der Voet, Hilko; de Sousa, Georges; Rorije, Emiel; Kumar, Vikas; de Boer, Waldo; Kruisselbrink, Johannes W.; Bois, Frederic Y.; Faniband, Moosa; Moretto, Angelo; Brochot, Celine

Considerations and Caveats when Applying Global Sensitivity Analysis Methods to Physiologically Based Pharmacokinetic Models

AAPS JOURNAL

IF3.7

2020-07-17

OAAI

Liu, Dan; Li, Linzhong; Rostami-Hodjegan, Amin; Bois, Frederic Y.; Jamei, Masoud

Development of a generic zebrafish embryo PBPK model and application to the developmental toxicity assessment of valproic acid analogs

REPRODUCTIVE TOXICOLOGY

IF2.8

2020-04-01

OAAI

Simeon, Segolene; Brotzmann, Katharina; Fisher, Ciaran; Gardner, Iain; Silvester, Steve; Maclennan, Richard; Walker, Paul; Braunbeck, Thomas; Bois, Frederic Y.

Prediction of maternal and foetal exposures to perfluoroalkyl compounds in a Spanish birth cohort using toxicokinetic modelling

TOXICOLOGY AND APPLIED PHARMACOLOGY

IF3.4

2019-09-01

OAAI

Brochot, Celine; Casas, Maribel; Manzano-Salgado, Cyntia; Zeman, Florence A.; Schettgen, Thomas; Vrijheid, Martine; Bois, Frederic Y.

研究方向