Characterization of Stable Pyrazole Derivatives of Curcumin with Improved Cytotoxicity on Osteosarcoma Cell LinesLIFE-BASELIF3.42023-02-035OAAI
Design, synthesis, in vitro antiproliferative activity and apoptosis-inducing studies of 1-(3′,4′,5′-trimethoxyphenyl)-3-(2′-alkoxycarbonylindolyl)-2-propen-1-one derivatives obtained by a molecular hybridisation approachJOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRYIF5.42018-08-2415OAAI
Hemiasterlin derivative (R)(S)(S)-BF65 and Akt inhibitor MK-2206 synergistically inhibit SKOV3 ovarian cancer cell growthBIOCHEMICAL PHARMACOLOGYIF5.62016-08-017OAAI
A novel hybrid drug between two potent anti-tubulin agents as a potential prolonged anticancer approachEUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCESIF4.72016-08-018OAAI
Novel iodoacetamido benzoheterocyclic derivatives with potent antileukemic activity are inhibitors of STAT5 phosphorylationEUROPEAN JOURNAL OF MEDICINAL CHEMISTRYIF5.92016-01-018OAAI
4,5,6,7-Tetrahydro-isoxazolo-[4,5-c]pyridines as a new class of cytotoxic Hsp90 inhibitorsEUROPEAN JOURNAL OF MEDICINAL CHEMISTRYIF5.92014-04-0118PREAI
Novel 3,4-Isoxazolediamides as Potent Inhibitors of Chaperone Heat Shock Protein 90JOURNAL OF MEDICINAL CHEMISTRYIF6.82011-11-2339PRE
Development of hemiasterlin derivatives as potential anticancer agents that inhibit tubulin polymerization and synergize with a stilbene tubulin inhibitorINVESTIGATIONAL NEW DRUGSIF2.72011-06-0812PREAI
Inhibition of cell proliferation by a resveratrol analog in human pancreatic and breast cancer cellsEXPERIMENTAL AND MOLECULAR MEDICINEIF12.92009-01-0137OAAI
Design, synthesis and biological evaluation of novel stilbene-based antitumor agentsBIOORGANIC & MEDICINAL CHEMISTRYIF32009-01-0130PRE
Design, Synthesis, and Biological Evaluation of Novel Aminobisphosphonates Possessing an in Vivo Antitumor Activity Through a γδ-T Lymphocytes-Mediated Activation MechanismJOURNAL OF MEDICINAL CHEMISTRYIF6.82008-10-2180PREAI
Novel A-ring and B-ring modified combretastatin A-4 (CA-4) analogues endowed with interesting cytotoxic activity具有有趣细胞毒活性的新型A环和B环修饰的combretastatin A-4 (CA-4) 类似物JOURNAL OF MEDICINAL CHEMISTRYIF6.82008-09-1162PREAI
Novel terphenyls and 3,5-diaryl isoxazole derivatives endowed with growth supporting and antiapoptotic propertiesJOURNAL OF MEDICINAL CHEMISTRYIF6.82008-07-1243PREAI
Novel combretastatin analogues endowed with antitumor activityJOURNAL OF MEDICINAL CHEMISTRYIF6.82006-05-06116PREAI
Studies on the apoptotic activity of natural and synthetic retinoids: Discovery of a new class of synthetic terphenyls that potently support cell growth and inhibit apoptosis in neuronal and HL-60 cellsJOURNAL OF MEDICINAL CHEMISTRYIF6.82005-06-0338PREAI
Synthesis and pharmacology of 6-substituted benztropines: Discovery of novel dopamine uptake inhibitors possessing low binding affinity to the dopamine transporterJOURNAL OF MEDICINAL CHEMISTRYIF6.82005-04-0514OA
Heterocyclic and phenyl double-bond-locked combretastatin analogues possessing potent apoptosis-inducing activity in HL60 and in MDR cell linesJOURNAL OF MEDICINAL CHEMISTRYIF6.82005-01-12168PREAI
Synthesis and biological evaluation of resveratrol and analogues as apoptosis-inducing agentsJOURNAL OF MEDICINAL CHEMISTRYIF6.82003-07-01235PREAI
Heterocycle-containing retinoids. Discovery of a novel isoxazole arotinoid possessing potent apoptotic activity in multidrug and drug-induced apoptosis-resistant cellsJOURNAL OF MEDICINAL CHEMISTRYIF6.82001-06-02112PREAI