Changjun Zhang

Zhejiang University of Technology

H指数:16

被引数:764

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Design, synthesis, and evaluation of novel 5-aminolevulinic acid and 3-hydroxypyridinone conjugates for enhanced photodynamic therapy in triple-negative breast cancer

新型5-氨基乙酰丙酸和3-羟基吡啶酮缀合物的设计、合成及其在增强三阴性乳腺癌光动力疗法中的应用评价

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

IF2.2

2026-08-010

PRE

Dual-masked cathepsin B-activated 5-aminolevulinic acid prodrugs with enhanced photodynamic cytotoxicity

双遮蔽的半胱天冬酶B激活的5-氨基乙酰丙酸前药，具有增强的光动力细胞毒性

Bioorganic Chemistry

IF4.7

2026-07-070

PRE

Electrochemical Tandem Cyclization of N-(But-3-en-1-yl)Anilines to Access Trifluoromethylated Tetrahydroquinoline Derivatives

电化学串联环化N-(丁-3-烯-1-基)苯胺以制备三氟甲基化四氢喹啉衍生物

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

IF2.7

2025-10-010

PRE

Visible-Light Driven Radical Cyclization Strategy for C(sp3)―CH2CF3―Functional Tetrahydroquinoline Derivatives

可见光驱动的自由基环化策略用于C(sp³)―CH₂CF₃―官能化四氢喹啉衍生物

ASIAN JOURNAL OF ORGANIC CHEMISTRY

IF2.7

2025-09-010

PRE

Catalytic Electron-Acceptor Mediated C(sp2)–H Sulfoxidation Reactions

催化电子受体介导的C(sp2)–H磺氧化反应

Green Chem.

IF9.2

2025-08-250

PRE

3-Hydroxyquinolin-2-Ones Act as Dual Inhibitors of Ferroptosis and Monoamine Oxidase B: Reducing Alzheimer’s Disease-Related Amyloid Precursor Protein and Hyperphosphorylated Tau In Vivo

3-羟基喹啉-2-酮作为铁死亡和单胺氧化酶B的双重抑制剂：体内降低阿尔茨海默病相关的淀粉样前体蛋白和过度磷酸化Tau

Journal of Medicinal Chemistry

IF6.8

2025-06-210

PRE

A dual-radical process for tri/di-fluoromethylarylation of alkenes enabled by indirect electroreduction

CHEMICAL COMMUNICATIONS

IF4.2

2025-04-010

PRE

Discovery of novel benzimidazole derivatives as selective and reversible monoamine oxidase B inhibitors for Parkinson's disease treatment

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2024-08-012

PRE

Comprehensive safety evaluation of a novel multitargeting compound XYY-CP1106: A candidate for Alzheimer's disease

BIOMEDICINE & PHARMACOTHERAPY

IF7.5

2024-07-010

OAAI

One-Pot Multicomponent Selective Synthesis of 5-Trifluoromethyl Pyrimidine Derivatives

ADVANCED SYNTHESIS & CATALYSIS

IF4

2024-06-160

PRE

Photodynamic anticancer activity evaluation of novel 5-aminolevulinic acid and 3-hydroxypyridinone conjugates

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2024-05-011

PRE

Novel 3-hydroxypyridin-4(1H)-One derivatives as ferroptosis inhibitors with iron-chelating and reactive oxygen species scavenging activities and therapeutic effect in cisplatin-induced cytotoxicity

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2024-01-013

PRE

A photoinduced multicomponent intramolecular cyclization/hydroxytrifluoromethylation cascade: facile access to polyfunctionalized 3,4-dihydroquinazolinones

GREEN CHEMISTRY

IF9.2

2024-01-011

PRE

Latest advances in dual inhibitors of acetylcholinesterase and monoamine oxidase B against Alzheimer's disease

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

IF5.4

2023-11-1310

OAAI

Monoamine oxidase B inhibitors based on natural privileged scaffolds: A review of systematically structural modification

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

IF8.5

2023-11-018

PRE

Study on Absorption, Distribution and Excretion of a New Candidate Compound XYY-CP1106 against Alzheimer's Disease in Rats by LC-MS/MS

MOLECULES

IF4.6

2023-03-041

OAAI

Synthesis of P-stereogenic cyclicphosphinic amidesviaelectrochemically enabled cobalt-catalyzed enantioselective C–H annulation

Green Chemistry

IF9.2

2023-01-0128

PRE

Chromone-based monoamine oxidase B inhibitor with potential iron-chelating activity for the treatment of Alzheimer's disease

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

IF5.4

2022-12-1512

OAAI

Design and synthesis of novel stilbene-hydroxypyridinone hybrids as tyrosinase inhibitors and their application in the anti-browning of freshly-cut apples

FOOD CHEMISTRY

IF9.8

2022-08-0132

PRE

Discovery of benzamide-hydroxypyridinone hybrids as potent multi-targeting agents for the treatment of Alzheimer's disease

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

IF5.4

2021-10-046

OAAI

Changjun Zhang

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