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收藏M021 (rhGAA) has a unique glycosylation profile which enables more efficient glycogen reduction and may allow for alternative Pompe ERT dosing strategies
Gray, Kylie J.; DiGruccio, Michael; Roberts, Jonathan; Weaver, Vaughn; Marcinczyk, Riley; Lyons, Linda; Wanninayake, Udayanga; Liu, Shou; Brignol, Nastry; Sheikh, Osman; Booth, Clarissa; Ortmeier, Steven B.; White, Katherine; Do, Hung; Gotshall, Russell
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收藏Hyperactive GlcNAc-1-Phosphotransferase (S1S3 PTase) dramatically increases M6P levels on lysosomal enzymes for substantially improved receptor binding and cellular uptake
DiGruccio, Michael R.; Gray, Kylie; Marcinczyk, Riley; Roberts, Jonathan; Wanninayake, Udayanga; Weaver, Vaughn; Liu, Shou; Brignol, Nastry; Sheikh, Osman; Booth, Clarissa; White, Katherine; Liu, Lin; Do, Hung; Gotshall, Russell
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收藏M021: rhGAA with optimal glycosylation profile containing very high levels of bis-phosphorylated N-glycans clears accumulated glycogen and rapidly normalizes muscle strength in treated Pompe disease mice
Gotschall, Russell; DiGruccio, Michael; Gray, Kylie; Lyons, Linda; Marcinczyk, Riley; Roberts, Jonathan; Wanninayake, Udayanga; Weaver, Vaughn; Gotschall, Lydia R.; Booth, Clarissa; Moser, Rebecca; Ortmeier, Steven B.; White, Katherine; Forred, Benjamin; Liu, Lin; Do, Hung
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收藏The Baby Steps Web Program for the Well-Being of New Parents: Randomized Controlled Trial婴儿步骤网络计划对新父母的福祉: 随机对照试验
Kavanagh, David John; Connolly, Jennifer; Fisher, Jane; Halford, W. Kim; Hamilton, Kyra; Hides, Leanne; Milgrom, Jeannette; Rowe, Heather; Scuffham, Paul A.; White, Katherine M.; Wittkowski, Anja; Appleton, Shelley; Sanders, Davina
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