Targeting transcription factors through an IMiD independent zinc finger domain通过IMiD非依赖性锌指域靶向转录因子EMBO MOLECULAR MEDICINEIF8.32025-05-140OA
Redox Cycling Dioxonaphthoimidazoliums Disrupt Iron Homeostasis in Mycobacterium bovis Bacillus Calmette-GuerinMICROBIOLOGY SPECTRUMIF3.82022-12-212OAAI
Alkyltriphenylphosphonium turns naphthoquinoneimidazoles into potent membrane depolarizers against mycobacteriaRSC MEDICINAL CHEMISTRYIF3.62022-01-012OAAI
Functionalized Dioxonaphthoimidazoliums: A Redox Cycling Chemotype with Potent Bactericidal Activities against Mycobacterium tuberculosisJOURNAL OF MEDICINAL CHEMISTRYIF6.82021-10-2711OA
High-Content Phenotypic Screen of a Focused TCAMS Drug Library Identifies Novel Disruptors of the Malaria Parasite Calcium DynamicsACS CHEMICAL BIOLOGYIF3.82021-10-054PREAI
Mechanism-Based Inactivation of Cytochrome P450 3A4 and 3A5 by the Fibroblast Growth Factor Receptor Inhibitor ErdafitinibCHEMICAL RESEARCH IN TOXICOLOGYIF3.82021-06-3011PREAI
Resistance against Membrane-Inserting MmpL3 Inhibitor through Upregulation of MmpL5 in Mycobacterium tuberculosisANTIMICROBIAL AGENTS AND CHEMOTHERAPYIF4.52020-11-173OAAI
Amide-Amine Replacement in Indole-2-carboxamides Yields Potent Mycobactericidal Agents with Improved Water SolubilityACS MEDICINAL CHEMISTRY LETTERSIF42020-11-1610OAAI
Potency Increase of Spiroketal Analogs of Membrane Inserting Indolyl Mannich Base Antimycobacterials Is Due to Acquisition of MmpL3 InhibitionACS INFECTIOUS DISEASESIF3.82020-05-1516OAAI
Extreme Drug Tolerance of Mycobacterium abscessus PersistersFRONTIERS IN MICROBIOLOGYIF4.52020-03-0458OAAI
Rifabutin Suppresses Inducible Clarithromycin Resistance in Mycobacterium abscessus by Blocking Induction of whiB7 and erm41ANTIBIOTICS-BASELIF4.62020-02-1027OAAI
Antimalarial N1,N3-Dialkyldioxonaphthoimidazoliums: Synthesis, Biological Activity, and Structure-activity RelationshipsACS MEDICINAL CHEMISTRY LETTERSIF42019-12-1114OAAI
Galloyl esters of trans-stilbenes are inhibitors of FASN with anticancer activity on non-small cell lung cancer cellsEUROPEAN JOURNAL OF MEDICINAL CHEMISTRYIF5.92019-11-0118PREAI
Gut Microbiota Metabolite Indole Propionic Acid Targets Tryptophan Biosynthesis in Mycobacterium tuberculosisMBIOIF4.72019-04-3070OAAI
The Mycobacterial Membrane: A Novel Target Space for Anti-tubercular DrugsFRONTIERS IN MICROBIOLOGYIF4.52018-07-1936OAAI
Anti-survivin effect of the small molecule inhibitor YM155 in RCC cells is mediated by time-dependent inhibition of the NF-κB pathwaySCIENTIFIC REPORTSIF3.92018-07-0612OAAI
Indolyl Azaspiroketal Mannich Bases Are Potent Antimycobacterial Agents with Selective Membrane Permeabilizing Effects and in Vivo ActivityJOURNAL OF MEDICINAL CHEMISTRYIF6.82018-06-1229OAAI
The mechanistic effects of the dioxonaphthoimidazolium analog YM155 in renal cell carcinoma cell cycling and apoptosisLIFE SCIENCESIF5.12018-06-015PREAI
A New Generation of Arachidonic Acid Analogues as Potential Neurological Agent Targeting Cytosolic Phospholipase A2SCIENTIFIC REPORTSIF3.92017-10-2019OAAI
个人简介
教育背景
工作经历
荣誉奖项
未登录.png){kind=icon}
未登录个人简介教育背景工作经历荣誉奖项