Donald E. Mager - Publications, H-index & Citations

Donald E. Mager

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45H指数

228论文数

7.2K被引数

收录论文 104

发表时间

PK-PD Modeling Suggests Tumor Heterogeneity Limits Preclinical to Clinical Translation of Enzalutamide in Prostate Cancer PK-PD模型表明肿瘤异质性限制了恩扎卢胺在前列腺癌中从临床前研究到临床试验的转化

Pharmaceutical Research

IF4.3

2026-05-05

PREAI

Se Jin Kim; Robert Bies; Donald E. Mager

Translatability of Animal Models for Alzheimer's Disease Using a Machine Learning Based Workflow 基于机器学习工作流程的阿尔茨海默病动物模型的可翻译性

CTS-CLINICAL AND TRANSLATIONAL SCIENCE

IF2.8

2025-11-18

OAAI

Foster-powell, Alex; Meno-tetang, Guy; Rostami-hodjegan, Amin; Ogungbenro, Kayode; Mager, Donald E.

B Cell Differentiation Model for Identifying Predictors of Responses to Rituximab-Mediated B Cell Depletion in Rheumatic Diseases B细胞分化模型：用于识别类风湿性疾病中利妥昔单抗介导的B细胞清除反应的预测因子

CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY

IF3

2025-11-01

OAAI

Nakada, Tomohisa; Mager, Donald E.

Multi-Species Minimal Physiologically-based Pharmacokinetic-Pharmacodynamic (mPBPK-PD) Model of Antisense Oligonucleotides for CNS Disorders 多物种最小生理基础药代动力学-药效动力学（mPBPK-PD）模型在反义寡核苷酸治疗中枢神经系统疾病中的应用

Drug Metabolism and Disposition

IF4

2025-09-24

PREAI

Devam A. Desai; Mfonabasi E. Ette; Dhaval K. Shah; Donald E. Mager

Mathematical Modeling of Neuroinflammation in Neurodegenerative Diseases 神经退行性疾病中神经炎症的数学建模

cpt pharmacometrics systems pharmacology

IF0

2025-08-13

OAAI

Alex Foster-Powell; Amin Rostami-Hodjegan; Guy Meno-Tetang; Donald E. Mager; Kayode Ogungbenro

Population Pharmacokinetic and Pharmacokinetic-Pharmacodynamic Modeling of Serum M-Protein Response for Modakafusp Alfa in a Phase 1/2 Study of Patients With Relapsed or Refractory Multiple Myeloma Modakafusp Alfa在复发或难治性多发性骨髓瘤患者的一项1/2期研究中，血清M蛋白反应的群体药代动力学和药代动力学-药效动力学建模

cts clinical and translational science

IF0

2025-07-21

OAAI

Cheryl Li; Andrew Santulli; Scott Van Wart; Lili Yang; Kaveri Suryanarayan; Sarah F. Cook; Xavier Parot; Donald E. Mager; Neeraj Gupta

Pharmaceutical Sciences: Insights and Observations from Academic Chairs and Vice Chairs

AAPS JOURNAL

IF3.7

2025-02-04

OAAI

Ainslie, Kristy M.; Bowers, Albert A.; Chichewicz, Robert H.; Collier, Lara S.; Doorn, Jonathan A.; Frei, Christopher R.; Ghandehari, Hamidreza; Gibbs, Robert B.; Lawrence, David S.; Lee, Craig R.; Mager, Donald E.; Marker, Paul; Schwendeman, Anna; Suryanarayanan, Raj; Williams, Robert O.; Xi, Yaguang; Xie, Wen; Xie, Xiang-Qun; Zhu, Guizhi; Nguyen, Juliane

Immune regulatory adjuvant approach to mitigate subcutaneous immunogenicity of monoclonal antibodies

FRONTIERS IN IMMUNOLOGY

IF5.9

2024-12-10

OAAI

Jarvi, Nicole L.; Patel, Manali; Shetty, Krithika A.; Nguyen, Nhan H.; Grasperge, Brooke F.; Mager, Donald E.; Straubinger, Robert M.; Balu-Iyer, Sathy V.

Challenges with sirolimus experimental data to inform QSP model of post-transplantation cyclophosphamide regimens

CTS-CLINICAL AND TRANSLATIONAL SCIENCE

IF2.8

2024-08-20

OAAI

Mohanan, Ezhilpavai; Shen, Guofang; Ren, Suping; Fan, Hsuan-Hao; Moua, Kao Tang Ying; Karolak, Aleksandra; Rockne, Russell C.; Nakamura, Ryotaro; Horne, David A.; Kanakry, Christopher G.; Mager, Donald E.; McCune, Jeannine S.

Inter-Antibody Variability in the Clinical Pharmacokinetics of Monoclonal Antibodies Characterized Using Population Physiologically Based Pharmacokinetic Modeling

ANTIBODIES

IF2.7

2024-07-09

OAAI

Kumar, Mokshada; Lanke, Sravani; Yadav, Alka; Ette, Mfonabasi; Mager, Donald E.; Shah, Dhaval K.

Quantitative systems pharmacology modeling of tumor heterogeneity in response to BH3-mimetics using virtual tumors calibrated with cell viability assays

CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY

IF3

2024-05-15

OAAI

Derippe, Thibaud; Fouliard, Sylvain; Decleves, Xavier; Mager, Donald E.

Contributions of William Jusko to Development of Pharmacokinetic and Pharmacodynamic Models and Methods

JOURNAL OF PHARMACEUTICAL SCIENCES

IF3.8

2024-01-01

PREAI

Mager, Donald E.; Straubinger, Robert M.

Target Reserve and Turnover Parameters Determine Rightward Shift of Enalaprilat Potency From its Binding Affinity to the Angiotensin Converting Enzyme

JOURNAL OF PHARMACEUTICAL SCIENCES

IF3.8

2024-01-01

PREAI

Nguyen, Van Anh; Zhang, Li; Kagan, Leonid; Rowland, Malcolm; Mager, Donald E.

Integrated PK/PD Modeling Relates Smoothened Inhibitor Biomarkers to The Heterogeneous Intratumor Disposition of Cetuximab in Pancreatic Cancer Tumor Models

JOURNAL OF PHARMACEUTICAL SCIENCES

IF3.8

2024-01-01

OAAI

Wang, Jun; Chen, Ting; Ruszaj, Donna M.; Mager, Donald E.; Straubinger, Robert M.

Population Pharmacokinetics and Pharmacodynamics of Carfilzomib in Combination with Rituximab, Ifosfamide, Carboplatin, and Etoposide in Adult Patients with Relapsed/Refractory Diffuse Large B Cell Lymphoma

TARGETED ONCOLOGY

IF4

2023-08-26

OAAI

Lin, Lan-Hsi; Ghasemi, Mohammad; Burke, Sarah M.; Mavis, Cory K.; Nichols, Jenna R.; Torka, Pallawi; Mager, Donald E.; Hernandez-Ilizaliturri, Francisco J.; Goey, Andrew K. L.

FOLFIRINOX Pharmacodynamic Interactions in 2D and 3D Pancreatic Cancer Cell Cultures

AAPS JOURNAL

IF3.7

2022-10-13

OAAI

Allen-Coyle, Taylor J.; Niu, Jin; Welsch, Eva; Conlon, Neil T.; Garner, Weylon; Clynes, Martin; O'Sullivan, Finbarr; Straubinger, Robert M.; Mager, Donald E.; Roche, Sandra

Systems model identifies baseline cytokine concentrations as potential predictors of rheumatoid arthritis inflammatory response to biologics

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2022-04-22

OAAI

Nakada, Tomohisa; Mager, Donald E.

Metabolic adaptation of ovarian tumors in patients treated with an IDO1 inhibitor constrains antitumor immune responses

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2022-03-16

OAAI

Odunsi, Kunle; Qian, Feng; Lugade, Amit A.; Yu, Han; Geller, Melissa A.; Fling, Steven P.; Kaiser, Judith C.; Lacroix, Andreanne M.; D'Amico, Leonard; Ramchurren, Nirasha; Morishima, Chihiro; Disis, Mary L.; Dennis, Lucas; Danaher, Patrick; Warren, Sarah; Van Anh Nguyen; Ravi, Sudharshan; Tsuji, Takemasa; Rosario, Spencer; Zha, Wenjuan; Hutson, Alan; Liu, Song; Lele, Shashikant; Zsiros, Emese; McGray, A. J. Robert; Chiello, Jessie; Koya, Richard; Chodon, Thinle; Morrison, Carl D.; Putluri, Vasanta; Putluri, Nagireddy; Mager, Donald E.; Gunawan, Rudiyanto; Cheever, Martin A.; Battaglia, Sebastiano; Matsuzaki, Junko

Cluster Gauss-Newton and CellNOpt Parameter Estimation in a Small Protein Signaling Network of Vorinostat and Bortezomib Pharmacodynamics

AAPS JOURNAL

IF3.7

2021-10-07

OAAI

Niu, Jin; Nguyen, Van Anh; Ghasemi, Mohammad; Chen, Ting; Mager, Donald E.

Network-Based Systems Analysis Explains Sequence-Dependent Synergism of Bortezomib and Vorinostat in Multiple Myeloma 基于网络的系统分析解释了多发性骨髓瘤中硼替佐米和伏立诺他的序列依赖性协同作用

AAPS JOURNAL

IF3.7

2021-08-17

PREAI

Nanavati, Charvi; Mager, Donald E.

研究方向