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A

Alison Crawford

Regeneron
H指数:23
被引数:5,074

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A PD-1-targeted, receptor-masked IL-2 immunocytokine that engages IL-2Ra strengthens T cell-mediated anti-tumor therapies
CELL REPORTS MEDICINE
IF10.6
2024-10-010
OAAI
Wu, Jiaxi; Bloch, Nicolin; Chang, Aaron Y.; Bhavsar, Ramandeep; Wang, Qingqing; Crawford, Alison; DiLillo, David J.; Vazzana, Kristin; Mohrs, Katja; Dudgeon, Drew; Patel, Supriya; Ahmed, Hassan; Garg, Vidur; Amatulli, Michael; Antao, Olivia Q.; Yan, Yuetian; Wang, Shunhai; Ramos, Willy; Krueger, Pamela; Adler, Christina; Ni, Min; Wei, Yi; Guo, Chunguang; Macdonald, Lynn; Huang, Tammy; Ullman, Erica; Hermann, Aynur; Yancopoulos, George D.; Murphy, Andrew J.; Davis, Samuel; Olson, William C.; Lin, John C.; Smith, Eric; Zhang, Tong
REGN10597: A PD-1-targeted, receptor-masked wild type IL-2 with improved therapeutic window for cancer immunotherapy
MOLECULAR CANCER THERAPEUTICS
IF5.5
2023-12-010
PRE
Wu, Jiaxi; Bloch, Nicolin; Chang, Aaron; Bhaysar, Ramandeep; Wang, Qingqing; Patel, Supriya; Garg, Vidur; Shakil, Hassan; Amatulli, Michael; Dudgeon, Drew; Yan, Yuetian; Wang, Shunhai; Ramos, Willy; Krueger, Pamela; Vazzana, Kristin; Crawford, Alison; Idun, Jacqueline; Decker, Corinne; DiLillo, David; Chandwani, Samira; Huang, Tammy; Kirshner, Jessica; Guo, Chungguang; Macdonald, Lynn; Ullman, Erica; Hermann, Aynur; Olson, William; Davis, Samuel; Lin, John; Smith, Eric; Zhang, Tong
Generation of T-cell-redirecting bispecific antibodies with differentiated profiles of cytokine release and biodistribution by CD3 affinity tuning

通过CD3亲和力调节产生具有细胞因子释放和生物分布的分化特征的T细胞重定向双特异性抗体

SCIENTIFIC REPORTS
IF3.9
2021-07-1364
OAAI
Haber, Lauric; Olson, Kara; Kelly, Marcus P.; Crawford, Alison; DiLillo, David J.; Tavare, Richard; Ullman, Erica; Mao, Shu; Canova, Lauren; Sineshchekova, Olga; Finney, Jennifer; Pawashe, Arpita; Patel, Supriya; McKay, Ryan; Rizvi, Sahar; Damko, Ermelinda; Chiu, Danica; Vazzana, Kristin; Ram, Priyanka; Mohrs, Katja; D'Orvilliers, Amanda; Xiao, Jenny; Makonnen, Sosina; Hickey, Carlos; Arnold, Cody; Giurleo, Jason; Chen, Ya Ping; Thwaites, Courtney; Dudgeon, Drew; Bray, Kevin; Rafique, Ashique; Huang, Tammy; Delfino, Frank; Hermann, Aynur; Kirshner, Jessica R.; Retter, Marc W.; Babb, Robert; MacDonald, Douglas; Chen, Gang; Olson, William C.; Thurston, Gavin; Davis, Samuel; Lin, John C.; Smith, Eric
Selection of CD3 affinity allows generation of T-cell redirecting bispecific antibodies with unique pharmacokinetic and biodistribution properties
CANCER RESEARCH
IF16.6
2020-08-151
PRE
Haber, Lauric; Olson, Kara; Babb, Robert; Kelly, Marcus; Crawford, Alison; Retter, Marc; DiLillo, David; Ullman, Erica; Finney, Jennifer; Canova, Lauren; Pawashe, Arpita; Chiu, Danica; Vazzana, Kristin; Ram, Priyanka; Mohrs, Katja; Dorvilliers, Amanda; Xiao, Jenny; Makonnen, Sosina; Hickey, Carlos; Arnold, Cody; Giurleo, Jason; Patel, Supriya; Tavare, Richard; Chen, Ya Ping; Chen, Gang; Olson, William; Thurston, Gavin; Lin, John Chia-Yang; Hermann, Aynur; Kirshner, Jessica; Smith, Eric J.
A class of costimulatory CD28-bispecific antibodies that enhance the antitumor activity of CD3-bispecific antibodies

一类增强CD3-bispecific抗体抗肿瘤活性的共刺激CD28-bispecific抗体

SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2020-01-0894
OAAI
Skokos, Dimitris; Waite, Janelle C.; Haber, Lauric; Crawford, Alison; Hermann, Aynur; Ullman, Erica; Slim, Rabih; Godin, Stephen; Ajithdoss, Dharani; Ye, Xuan; Wang, Bei; Wu, Qi; Ramos, Ilyssa; Pawashe, Arpita; Canova, Lauren; Vazzana, Kristin; Ram, Priyanka; Herlihy, Evan; Ahmed, Hassan; Oswald, Erin; Golubov, Jacquelynn; Poon, Patrick; Havel, Lauren; Chiu, Danica; Lazo, Miguel; Provoncha, Kathleen; Yu, Kevin; Kim, Julie; Warsaw, Jacqueline J.; Oristian, Nicole Stokes; Siao, Chia-Jen; Dudgeon, Drew; Huang, Tammy; Potocky, Terra; Martin, Joel; MacDonald, Douglas; Oyejide, Adelekan; Rafique, Ashique; Poueymirou, William; Kirshner, Jessica R.; Smith, Eric; Olson, William; Lin, John; Thurston, Gavin; Sleeman, Matthew A.; Murphy, Andrew J.; Yancopoulos, George D.
A Mucin 16 bispecific T cell-engaging antibody for the treatment of ovarian cancer
SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2019-06-19100
OAAI
Crawford, Alison; Haber, Lauric; Kelly, Marcus P.; Vazzana, Kristin; Canova, Lauren; Ram, Priyanka; Pawashe, Arpita; Finney, Jennifer; Jalal, Sumreen; Chiu, Danica; Colleton, Curtis A.; Garnova, Elena; Makonnen, Sosina; Hickey, Carlos; Krueger, Pamela; DelFino, Frank; Potocky, Terra; Kuhnert, Jessica; Godin, Stephen; Retter, Marc W.; Duramad, Paurene; MacDonald, Douglas; Olson, William C.; Fairhurst, Jeanette; Huang, Tammy; Martin, Joel; Lin, John C.; Smith, Eric; Thurston, Gavin; Kirshner, Jessica R.
Transcriptional analysis of HIV-specific CD8+ T cells shows that PD-1 inhibits T cell function by upregulating BATF
NATURE MEDICINE
IF50
2010-10-03485
OAAI
Quigley, Michael; Pereyra, Florencia; Nilsson, Bjoern; Porichis, Filippos; Fonseca, Catia; Eichbaum, Quentin; Julg, Boris; Jesneck, Jonathan L.; Brosnahan, Kathleen; Imam, Sabrina; Russell, Kate; Toth, Ildiko; Piechocka-Trocha, Alicja; Dolfi, Douglas; Angelosanto, Jill; Crawford, Alison; Shin, Haina; Kwon, Douglas S.; Zupkosky, Jennifer; Francisco, Loise; Freeman, Gordon J.; Wherry, E. John; Kaufmann, Daniel E.; Walker, Bruce D.; Ebert, Benjamin; Haining, W. Nicholas

研究方向

暂未获取到该数据
E
E. John Wherry
H 指数:142论文数:644被引数:10.9万
J
John Lin
H 指数:33论文数:116被引数:4,082
K
Kristin Vazzana
H 指数:6论文数:24被引数:472
J
Jessica R. Kirshner
H 指数:22论文数:111被引数:3,540
L
Lauric Haber
H 指数:11论文数:23被引数:1,322
W
William C. Olson
H 指数:58论文数:379被引数:1.4万
J
Jill Angelosanto
H 指数:17论文数:39被引数:6,679
G
Gavin Thurston
H 指数:79论文数:489被引数:3.1万
A
Aynur Hermann
H 指数:10论文数:71被引数:2,182
E
Erica Ullman
H 指数:12论文数:84被引数:2,141