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M

Mohamed T. M. Nemr

cairo university
H指数:18
被引数:856

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Novel 3,4-diaminothieno[2,3-b]thiophene-2,5-dicarbohydrazide-based scaffolds as EGFRWT, EGFRT790M, and tubulin polymerization inhibitors with anti-proliferative activity

新型3,4-二氨基噻吩[2,3-b]噻吩-2,5-二羰基肼基骨架作为EGFRWT、EGFRT790M和微管蛋白聚合抑制剂，并具有抗增殖活性

Bioorganic Chemistry
IF4.7
2025-07-080
PRE
Moustafa O. Aboelez; Mahmoud Abd El Aleem Ali Ali El-Remaily; Moumen S. Kamel; Omkulthom Al kamaly; Wael A.A. Fadaly; Mohamed T.M. Nemr; Hend A.A. Ezelarab
Design and Synthesis of New pyrazole Hybrids Linked to Oxime and Nitrate Moieties as COX-2, EGFRL858R/T790M Inhibitors and Nitric Oxide Donors with dual Anti-inflammatory/Anti-proliferative Activities

新型吡唑杂合物及其与肟基和硝酸根基团连接的设计与合成，作为COX-2、EGFRL858R/T790M抑制剂以及具有双重抗炎/抗增殖活性的亚硝酸盐供体

BIOORGANIC CHEMISTRY
IF4.7
2025-07-010
PRE
Fadaly, Wael A. A.; Nemr, Mohamed T. M.; El-Hameed, Abeer M. Abd; Mohamed, Fatma E. A.; Zidan, Taha H.
Synthesis and apoptotic induction of sulfonamide-based chalcone hybrids as first-in-class dual histone deacetylase‑carbonic anhydrase inhibitors with potential anti-tubulin activity

基于磺酰胺的查尔酮杂合物的合成及其作为第一类组蛋白去乙酰化酶-碳酸酐酶抑制剂的凋亡诱导作用，并具有潜在的抗微管活性

Bioorganic Chemistry
IF4.7
2025-06-200
PRE
Mamdouh F.A. Mohamed; Ibrahim M. Salem; Ali Fouad; Rasha M. Allam; Wael A.A. Fadaly; Mohamed T.M. Nemr; Sara Y. Ewieda; Tarek S. Ibrahim; Nashwa A. Ibrahim; Mahrous A. Abou-Salim
Discovery of novel thiazolopyrimidine derivatives targeting topoisomerase II: Design, synthesis, antiproliferative evaluation, molecular docking and apoptosis inducing activity

靶向拓扑异构酶II的新型噻唑嘧啶衍生物的发现：设计、合成、抗增殖评价、分子对接及诱导凋亡活性

Bioorganic Chemistry
IF4.7
2025-06-060
PRE
Sara Y. Ewieda; Mo'men Salem; Ahmed Elshewy; Mohnad Abdalla; May El-Manawaty; Hoda Khalifa Abdelhady; Haredy Hassan Haredy; Wael A.A. Fadaly; Mamdouh F.A. Mohamed; Mohamed T.M. Nemr
Design, Synthesis and Biological Evaluation of Phenoxyacetic Acid derivatives Linked to Pyrazole Scaffold as PPAR-α/γ Agonists and COX-2 Inhibitors with Dual Antidiabetic/Anti-inflammatory Activities

基于吡唑骨架连接的苯氧乙酸衍生物的设计、合成及其作为PPAR-α/γ激动剂和COX-2抑制剂的抗糖尿病/抗炎双重活性生物评价

JOURNAL OF MOLECULAR STRUCTURE
IF4.7
2025-05-240
PRE
Fadaly, Wael A. A.; Amin, Dina M. E.; Bakr, Rania B.; Nemr, Mohamed T. M.; Ismail, Basma S.; Mohamed, Mamdouh F. A.
Novel pyrazole carboxylate derivatives as lonazolac bioisosteres with selective COX-2 inhibition: design, synthesis and anti-inflammatory activity

新型吡唑羧酸酯衍生物作为lonazolac的生物电子等排体，具有选择性COX-2抑制：设计、合成及抗炎活性

MOLECULAR DIVERSITY
IF3.8
2025-05-220
OA
Fadaly, Wael A. A.; Elshewy, Ahmed; Abusabaa, Ahmed H. A.; Amin, Dina M. E.; Abdelhady, Hoda Khalifa; Haredy, Haredy Hassan; Mahmoud, Asmaa M.; Ibrahim, Nashwa A.; Nemr, Mohamed T. M.
New 1,2,3-triazole/1,2,4-triazole hybrids linked to oxime moiety as nitric oxide donor selective COX-2, aromatase, B-RAFV600E and EGFR inhibitors celecoxib analogs: design, synthesis, anti-inflammatory/anti-proliferative activities, apoptosis and molecular modeling study
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
IF5.4
2023-12-0713
OAAI
Fadaly, Wael A. A.; Nemr, Mohamed T. M.; Zidan, Taha H.; Mohamed, Fatma E. A.; Abdelhakeem, Marwa M.; Abu Jayab, Nour N.; Omar, Hany A.; Abdellatif, Khaled R. A.

研究方向

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W
Wael A. A. Fadaly
H 指数:20论文数:55被引数:955
Y
Yaseen A. M. M. Elshaier
H 指数:28论文数:92被引数:2,595
S
Sara Y Ewieda
H 指数:5论文数:15被引数:102
A
Ahmed Elshewy
H 指数:8论文数:27被引数:199
M
Mamdouh F. A. Mohamed
H 指数:24论文数:73被引数:1,810
T
Taha H. Zidan
H 指数:9论文数:17被引数:251
K
Khaled R.A. Abdellatif
H 指数:34论文数:115被引数:3,013
A
Abdelaziz, Mostafa A.
H 指数:0论文数:2被引数:13
D
Dina M. E. Amin
H 指数:4论文数:4被引数:112
F
Fatma E. A. Mohamed
H 指数:3论文数:7被引数:74