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M

Mamdouh F. A. Mohamed

sohag university
H指数:24
被引数:1,811

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Exploration of novel hydroxamic acid-based candidates integrating chalcone scaffold cap as multitarget HDAC inhibitors: design, anti-prostatic cancer assessment, in silico docking and molecular dynamic simulation

基于羟肟酸的含查尔酮骨架帽的新型候选物作为多靶点HDAC抑制剂的探索：设计、抗前列腺癌评估、计算机对接和分子动力学模拟

Journal of Enzyme Inhibition and Medicinal Chemistry
IF5.4
2026-08-270
OAAI
Aya I. Abd El-hameed; Ibrahim M. Salem; Rasha M. Allam; Mariem M. Arafat; Hossameldin A. Aziz; Zuhier A. Awan; Tarek S. Ibrahim; Omar Alshazly; Eman A. M. Beshr; Stefan Bräse; Mamdouh F. A. Mohamed
Design, Synthesis, In Silico Docking, Multitarget Bioevaluation and Molecular Dynamic Simulation of Novel Pyrazolo[3,4-d]Pyrimidinone Derivatives as Potential In Vitro and In Vivo Anti-Inflammatory Agents

设计、合成、计算机模拟对接、多靶点生物评价及分子动力学模拟新型吡唑并[3,4-d]嘧啶酮衍生物作为潜在的体外及体内抗炎剂

Pharmaceuticals 2025, Vol. 18, Page 1326
IF4.8
2025-09-040
OAAI
Mostafa Roshdi; Mamdouh F. A. Mohamed; Eman A. M. Beshr; Hossameldin A. Aziz; Sahar M. Gebril; Stefan Bräse; Aliaa M. Mohassab
Synthesis and apoptotic induction of sulfonamide-based chalcone hybrids as first-in-class dual histone deacetylase‑carbonic anhydrase inhibitors with potential anti-tubulin activity

基于磺酰胺的查尔酮杂合物的合成及其作为第一类组蛋白去乙酰化酶-碳酸酐酶抑制剂的凋亡诱导作用，并具有潜在的抗微管活性

Bioorganic Chemistry
IF4.7
2025-06-200
PRE
Mamdouh F.A. Mohamed; Ibrahim M. Salem; Ali Fouad; Rasha M. Allam; Wael A.A. Fadaly; Mohamed T.M. Nemr; Sara Y. Ewieda; Tarek S. Ibrahim; Nashwa A. Ibrahim; Mahrous A. Abou-Salim
Discovery of novel thiazolopyrimidine derivatives targeting topoisomerase II: Design, synthesis, antiproliferative evaluation, molecular docking and apoptosis inducing activity

靶向拓扑异构酶II的新型噻唑嘧啶衍生物的发现：设计、合成、抗增殖评价、分子对接及诱导凋亡活性

Bioorganic Chemistry
IF4.7
2025-06-060
PRE
Sara Y. Ewieda; Mo'men Salem; Ahmed Elshewy; Mohnad Abdalla; May El-Manawaty; Hoda Khalifa Abdelhady; Haredy Hassan Haredy; Wael A.A. Fadaly; Mamdouh F.A. Mohamed; Mohamed T.M. Nemr
Design, Synthesis and Biological Evaluation of Phenoxyacetic Acid derivatives Linked to Pyrazole Scaffold as PPAR-α/γ Agonists and COX-2 Inhibitors with Dual Antidiabetic/Anti-inflammatory Activities

基于吡唑骨架连接的苯氧乙酸衍生物的设计、合成及其作为PPAR-α/γ激动剂和COX-2抑制剂的抗糖尿病/抗炎双重活性生物评价

JOURNAL OF MOLECULAR STRUCTURE
IF4.7
2025-05-240
PRE
Fadaly, Wael A. A.; Amin, Dina M. E.; Bakr, Rania B.; Nemr, Mohamed T. M.; Ismail, Basma S.; Mohamed, Mamdouh F. A.

研究方向

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T
Tarek S. Ibrahim
H 指数:31论文数:111被引数:2,259
R
Rasha M. Allam
H 指数:18论文数:52被引数:1,177
G
Gamal El‐Din A. Abuo‐Rahma
H 指数:35论文数:135被引数:3,825
M
Mohamed T. M. Nemr
H 指数:18论文数:35被引数:856
M
Mohamed Badr
H 指数:14论文数:29被引数:545
W
Wael A. A. Fadaly
H 指数:20论文数:55被引数:955
O
Omar Alshazly
H 指数:3论文数:14被引数:35
A
Amr H. Moustafa
H 指数:16论文数:67被引数:655
A
Ahmad J. Almalki
H 指数:16论文数:40被引数:934
A
Amr K. A. Bass
H 指数:8论文数:14被引数:297