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H

Hugh A. Barton

united states environmental protection agency

H指数:39

被引数:4,638

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Predicting nonlinear relationships between external and internal concentrations with physiologically based pharmacokinetic modeling

TOXICOLOGY AND APPLIED PHARMACOLOGY

IF3.4

2022-04-017

OAAI

Opportunities and challenges related to saturation of toxicokinetic processes: Implications for risk assessment

REGULATORY TOXICOLOGY AND PHARMACOLOGY

IF3.5

2021-12-0113

OAAI

A Physiologically-Based Pharmacokinetic Model for the Prediction of Monoclonal Antibody Pharmacokinetics From In Vitro Data

CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY

IF3

2019-09-2339

OAAI

Moving beyond Binary Predictions of Human Drug-Induced Liver Injury (DILI) toward Contrasting Relative Risk Potential

CHEMICAL RESEARCH IN TOXICOLOGY

IF3.8

2019-09-1842

PREAI

Mechanistic Projection of First-in-Human Dose for Bispecific Immunomodulatory P-Cadherin LP-DART: An Integrated PK/PD Modeling Approach

双特异性免疫调节P-钙粘蛋白lp-dart的首次人体剂量的机制预测: 一种集成的PK/PD建模方法

CLINICAL PHARMACOLOGY & THERAPEUTICS

IF5.5

2016-07-2139

PREAI

Translational Modeling in Schizophrenia: Predicting Human Dopamine D2 Receptor Occupancy (vol 33, pg 1003, 2016)

PHARMACEUTICAL RESEARCH

IF4.3

2016-03-102

OAAI

Does the Systemic Plasma Profile Inform the Liver Profile? Analysis Using a Physiologically Based Pharmacokinetic Model and Individual Compounds

IF3.7

2016-03-0712

OAAI

Translational Modeling in Schizophrenia: Predicting Human Dopamine D2 Receptor Occupancy

PHARMACEUTICAL RESEARCH

IF4.3

2015-12-3014

OA

Setting Clinical Exposure Levels of Concern for Drug-Induced Liver Injury (DILI) Using Mechanistic in vitro Assays

TOXICOLOGICAL SCIENCES

IF4.1

2015-07-23116

OAAI

Dopamine D2 Receptor Occupancy as a Predictor of Catalepsy in Rats: A Pharmacokinetic-Pharmacodynamic Modeling Approach

PHARMACEUTICAL RESEARCH

IF4.3

2014-05-0312

PREAI

Case study illustrating the WHO IPCS guidance on characterization and application of physiologically based pharmacokinetic models in risk assessment

REGULATORY TOXICOLOGY AND PHARMACOLOGY

IF3.5

2013-06-0127

PREAI

Model-based approaches to predict drug-drug interactions associated with hepatic uptake transporters: preclinical, clinical and beyond

EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY

IF3.4

2013-01-2170

PREAI

Harmonization: Developing consistent guidelines for applying mode of action and dosimetry information to cancer and noncancer risk assessment

HUMAN AND ECOLOGICAL RISK ASSESSMENT

IF2.7

2010-06-0328

PREAI

Pharmacokinetic modeling of perfluorooctanoic acid during gestation and lactation in the mouse

REPRODUCTIVE TOXICOLOGY

IF2.8

2009-06-0118

PRE

Database for Physiologically Based Pharmacokinetic (PBPK) Modeling: Physiological Data for Healthy and Health-Impaired Elderly

JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS

IF8.1

2009-01-0888

PREAI

Modeling Single and Repeated Dose Pharmacokinetics of PFOA in Mice

TOXICOLOGICAL SCIENCES

IF4.1

2008-11-12102

OAAI

Agricultural chemical safety assessment: A multisector approach to the modernization of human safety requirements

CRITICAL REVIEWS IN TOXICOLOGY

IF4.1

2008-10-2048

PREAI

The acquisition and application of absorption, distribution, metabolism and excretion (ADME) data in agricultural chemical safety assessments

CRITICAL REVIEWS IN TOXICOLOGY

IF4.1

2008-10-10108

PREAI

Endocrine active compounds: From biology to dose response assessment

内分泌活性化合物: 从生物学到剂量反应评估

CRITICAL REVIEWS IN TOXICOLOGY

IF4.1

2008-09-2938

PREAI

Pharmacokinetics and dosimetry of the antiandrogen vinclozolin after oral administration in the rat

TOXICOLOGICAL SCIENCES

IF4.1

2008-08-1419

PREAI