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Alan H. Fairlamb

university of dundee
H指数:78
被引数:2.7万

个人简介

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荣誉奖项

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Multiple unbiased approaches identify oxidosqualene cyclase as the molecular target of a promising anti-leishmanial

多种无偏方法将氧化鲨烯环化酶鉴定为有希望的抗利什曼原药的分子靶标

CELL CHEMICAL BIOLOGY
IF7.2
2021-05-0114
OAAI
Paradela, Luciana S.; Wall, Richard J.; Carvalho, Sandra; Chemi, Giulia; Corpas-Lopez, Victoriano; Moynihan, Eoin; Bello, Davide; Patterson, Stephen; Guther, Maria Lucia S.; Fairlamb, Alan H.; Ferguson, Michael A. J.; Zuccotto, Fabio; Martin, Julio; Gilbert, Ian H.; Wyllie, Susan
Antikinetoplastid SAR study in 3-nitroimidazopyridine series: Identification of a novel non-genotoxic and potent anti-T.b. brucei hitcompound with improved pharmacokinetic properties
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
2020-11-0113
OAAI
Fersing, Cyril; Boudot, Clotilde; Paoli-Lombardo, Romain; Primas, Nicolas; Pinault, Emilie; Hutter, Sebastien; Castera-Ducros, Caroline; Kabri, Youssef; Pedron, Julien; Bourgeade-Delmas, Sandra; Sournia-Saquet, Alix; Stigliani, Jean-Luc; Valentin, Alexis; Azqueta, Amaya; Muruzabal, Damian; Destere, Alexandre; Wyllie, Susan; Fairlamb, Alan H.; Corvaisier, Sophie; Since, Marc; Malzert-Freon, Aurelie; Di Giorgio, Carole; Rathelot, Pascal; Azas, Nadine; Courtioux, Bertrand; Vanelle, Patrice; Verhaeghe, Pierre
8-Alkynyl-3-nitroimidazopyridines display potent antitrypanosomal activity against both T. b. brucei and cruzi
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
2020-09-0116
OAAI
Fersing, Cyril; Boudot, Clotilde; Castera-Ducros, Caroline; Pinault, Emilie; Hutter, Sebastien; Paoli-Lombardo, Romain; Primas, Nicolas; Pedron, Julien; Seguy, Line; Bourgeade-Delmas, Sandra; Sournia-Saquet, Alix; Stigliani, Jean-Luc; Brossas, Jean-Yves; Paris, Luc; Valentin, Alexis; Wyllie, Susan; Fairlamb, Alan H.; Boutet-Robinet, Elisa; Corvaisier, Sophie; Since, Marc; Malzert-Freon, Aurelie; Destere, Alexandre; Mazier, Dominique; Rathelot, Pascal; Courtioux, Bertrand; Azas, Nadine; Verhaeghe, Pierre; Vanelle, Patrice
New 8-Nitroquinolinone Derivative Displaying Submicromolar in Vitro Activities against Both Trypanosoma brucei and cruzi
ACS MEDICINAL CHEMISTRY LETTERS
IF4
2020-02-0610
OAAI
Pedron, Julien; Boudot, Clotilde; Brossas, Jean-Yves; Pinault, Emilie; Bourgeade-Delmas, Sandra; Sournia-Saquet, Alix; Boutet-Robinet, Elisa; Destere, Alexandre; Tronnet, Antoine; Berge, Justine; Bonduelle, Colin; Deraeve, Celine; Pratviel, Genevieve; Stigliani, Jean-Luc; Paris, Luc; Mazier, Dominique; Corvaisier, Sophie; Since, Marc; Malzert-Freon, Aureprimelie; Wyllie, Susan; Milne, Rachel; Fairlamb, Alan H.; Valentin, Alexis; Courtioux, Bertrand; Verhaeghe, Pierre
The Qi Site of Cytochrome b is a Promiscuous Drug Target in Trypanosoma cruzi and Leishmania donovani
ACS INFECTIOUS DISEASES
IF3.8
2020-01-2224
OAAI
Wall, Richard J.; Carvalho, Sandra; Milne, Rachel; Bueren-Calabuig, Juan A.; Moniz, Sonia; Cantizani-Perez, Juan; MacLean, Lorna; Kessler, Albane; Cotillo, Ignacio; Sastry, Lalitha; Manthri, Sujatha; Patterson, Stephen; Zuccotto, Fabio; Thompson, Stephen; Martin, Julio; Marco, Maria; Miles, Timothy J.; De Rycker, Manu; Thomas, Michael G.; Fairlamb, Alan H.; Gilbert, Ian H.; Wyllie, Susan
Substituted Aminoacetamides as Novel Leads for Malaria Treatment
CHEMMEDCHEM
IF3.4
2019-07-036
OAAI
Norcross, Neil R.; Wilson, Caroline; Baragana, Beatriz; Hallyburton, Irene; Osuna-Cabello, Maria; Norval, Suzanne; Riley, Jennifer; Fletcher, Daniel; Sinden, Robert; Delves, Michael; Ruecker, Andrea; Duffy, Sandra; Meister, Stephan; Antonova-Koch, Yevgeniya; Crespo, Benigno; de Cozar, Cristina; Sanz, Laura M.; Javier Gamo, Francisco; Avery, Vicky M.; Frearson, Julie A.; Gray, David W.; Fairlamb, Alan H.; Winzeler, Elizabeth A.; Waterson, David; Campbell, Simon F.; Willis, Paul A.; Read, Kevin D.; Gilbert, Ian H.
Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2019-04-08115
OAAI
Wyllie, Susan; Brand, Stephen; Thomas, Michael; De Rycker, Manu; Chung, Chun-wa; Pena, Imanol; Bingham, Ryan P.; Bueren-Calabuig, Juan A.; Cantizani, Juan; Cebrian, David; Craggs, Peter D.; Ferguson, Liam; Goswami, Panchali; Hobrath, Judith; Howe, Jonathan; Jeacock, Laura; Ko, Eun-Jung; Korczynska, Justyna; MacLean, Lorna; Manthri, Sujatha; Martinez, Maria S.; Mata-Cantero, Lydia; Moniz, Sonia; Nuhs, Andrea; Osuna-Cabello, Maria; Pinto, Erika; Riley, Jennifer; Robinson, Sharon; Rowland, Paul; Simeons, Frederick R. C.; Shishikura, Yoko; Spinks, Daniel; Stojanovski, Laste; Thomas, John; Thompson, Stephen; Gaza, Elisabet Viayna; Wall, Richard J.; Zuccotto, Fabio; Horn, David; Ferguson, Michael A. J.; Fairlamb, Alan H.; Fiandor, Jose M.; Martin, Julio; Gray, David W.; Miles, Timothy J.; Gilbert, Ian H.; Read, Kevin D.; Marco, Maria; Wyatt, Paul G.
Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2019-03-20111
OAAI
Baragana, Beatriz; Forte, Barbara; Choi, Ryan; Hewitt, Stephen Nakazawa; Bueren-Calabuig, Juan A.; Pisco, Joao Pedro; Peet, Caroline; Dranow, David M.; Robinson, David A.; Jansen, Chimed; Norcross, Neil R.; Vinayak, Sumiti; Anderson, Mark; Brooks, Carrie F.; Cooper, Caitlin A.; Damerow, Sebastian; Delves, Michael; Dowers, Karen; Duffy, James; Edwards, Thomas E.; Hallyburton, Irene; Horst, BenjaminG.; Hulverson, Matthew A.; Ferguson, Liam; Belen Jimenez-Diaz, Maria; Jumani, Rajiv S.; Lorimer, Donald D.; Love, Melissa S.; Maher, Steven; Matthews, Holly; McNamara, Casew.; Miller, Peter; O'Neill, Sandra; Ojo, Kayode K.; Osuna-Cabello, Maria; Pinto, Erika; Post, John; Riley, Jennifer; Rottmann, Matthias; Sanz, Laura M.; Scullion, Paul; Sharma, Arvind; Shepherd, Sharon M.; Shishikura, Yoko; Simeons, Frederick R. C.; Stebbins, Erin E.; Stojanovski, Laste; Straschil, Ursula; Tamaki, Fabio K.; Tamjar, Jevgenia; Torrie, Leah S.; Vantaux, Amelie; Witkowski, Benoit; Wittlin, Sergio; Yogavel, Manickam; Zuccotto, Fabio; Angulo-Barturen, Inigo; Sinden, Robert; Baum, Jake; Gamo, Francisco-Javier; Maser, Pascal; Kyle, Dennis E.; Winzeler, Elizabeth A.; Myler, Peter J.; Wyatt, Paul G.; Floyd, David; Matthews, David; Sharmao, Amit; Striepen, Boris; Huston, Christopher D.; Gray, David W.; Fairlamb, Alan H.; Pisliakov, Andrei V.; Walpole, Chris; Read, Kevin D.; Van Voorhis, Wesley C.; Gilbert, Ian H.
Nongenotoxic 3-Nitroimidazo[1,2-a]pyridines Are NTR1 Substrates That Display Potent in Vitro Antileishmanial Activity
ACS MEDICINAL CHEMISTRY LETTERS
IF4
2018-12-1936
OAAI
Fersing, Cyril; Basmaciyan, Louise; Boudot, Clotilde; Pedron, Julien; Hatter, Sebastien; Cohen, Anita; Castera-Ducros, Caroline; Primas, Nicolas; Laget, Michele; Casanova, Magali; Bourgeade-Delmas, Sandra; Piednoel, Melanie; Sournia-Saquet, Alix; Mbou, Valere Belle; Courtioux, Bertrand; Boutet-Robinet, Elisa; Since, Marc; Milne, Rachel; Wyllie, Susan; Fairlamb, Alan H.; Valentin, Alexis; Rathelot, Pascal; Verhaeghe, Pierre; Vanelle, Patrice; Azas, Nadine
Pharmacological Validation of N-Myristoyltransferase as a Drug Target in Leishmania donovani
ACS INFECTIOUS DISEASES
IF3.8
2018-11-0153
OAAI
Corpas-Lopez, Victoriano; Moniz, Sonia; Thomas, Michael; Wall, Richard J.; Torrie, Leah S.; Zander-Dinse, Dorothea; Tinti, Michele; Brand, Stephen; Stojanovski, Laste; Manthri, Sujatha; Hallyburton, Irene; Zuccotto, Fabio; Wyatt, Paul G.; De Rycker, Manu; Horn, David; Ferguson, Michael A. J.; Clos, Joachim; Read, Kevin D.; Fairlamb, Alan H.; Gilbert, Ian H.; Wyllie, Susan
8-Aryl-6-chloro-3-nitro-2-(phenylsulfonylmethyl)imidazo[1,2-a] pyridines as potent antitrypanosomatid molecules bioactivated by type 1 nitroreductases
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
2018-09-0116
OAAI
Fersing, Cyril; Boudot, Clotilde; Pedron, Julien; Hutter, Sebastien; Primas, Nicolas; Castera-Ducros, Caroline; Bourgeade-Delmas, Sandra; Sournia-Saquet, Alix; Moreau, Alain; Cohen, Anita; Stigliani, Jean-Luc; Pratviel, Genevieve; Crozet, Maxime D.; Wyllie, Susan; Fairlamb, Alan; Valentin, Alexis; Rathelot, Pascal; Azas, Nadine; Courtioux, Bertrand; Verhaeghe, Pierre; Vanelle, Patrice

研究方向

暂未获取到该数据
S
Susan Wyllie
H 指数:39论文数:120被引数:5,250
I
Ian H. Gilbert
H 指数:57论文数:333被引数:1.2万
K
Kevin D. Read
H 指数:45论文数:166被引数:7,224
P
Paul G. Wyatt
H 指数:49论文数:203被引数:9,013
J
Julie A. Frearson
H 指数:30论文数:113被引数:3,807
S
Stephen Patterson
H 指数:32论文数:122被引数:3,272
D
David W. Gray
H 指数:34论文数:116被引数:4,982
I
Irene Hallyburton
H 指数:21论文数:49被引数:2,444
M
Manu De Rycker
H 指数:26论文数:63被引数:2,573
L
Leah S. Torrie
H 指数:22论文数:68被引数:2,265