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Andrew B. Tobin

university of glasgow

52H指数
247论文数
8.5K被引数
收录论文 99
发表时间
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Sailing to a deeper understanding of malaria parasite invasion航行于对疟原虫入侵的更深层理解
errTrends in Parasitology
IF6.6
err2026-09-23
err0
errOAAI
errAndrew B. Tobin
err分享
err收藏
Low Agonism and Balanced Pathway Modulation Distinguish an M1 Muscarinic Receptor Positive Allosteric Modulator Lacking Cholinergic Adverse Effects低激动活性和平衡通路调节区分了一种缺乏胆碱能不良反应的M1毒蕈碱受体正向别构调节剂
errACS Chemical Neuroscience
IF3.9
err2026-06-30
err0
PREAI
errHuong T. M. Nguyen; Elham Khajehali; Vi Pham; John W. Scott; Toby A. Dite; Laura F. Dagley; James M. Murphy; Geoff Thompson; Andrew B. Tobin; David M. Thal; Arthur Christopoulos; Emma T. van der Westhuizen; Celine Valant
err分享
err收藏
Shaping Antimalarials: A Geometry-First Approach to PfCLK3 Covalent Inhibitors
errJournal of Medicinal Chemistry
IF6.8
err2026-01-31
err0
errOAAI
errSkye B. Brettell; Carla Fuentes-Guerra Bustos; Saumya Sharma; Gillian Cann; Lauren V. Carruthers; Abbey Begen; Graeme Milligan; David J. Clarke; Andrew B. Tobin; Andrew G. Jamieson
err分享
err收藏
Real-time wide-field fluorescence lifetime imaging via single-snapshot acquisition for biomedical applications基于单次快照采集的实时广域荧光寿命成像技术及其在生物医学中的应用
errPhotoniX
IF19.1
err2025-12-19
err0
errOAAI
errVikas Pandey; Euan Millar; Ismail Erbas; Luis Chavez; Jack Radford; Isaiah Crosbourne; Mansa Madhusudan; Gregor G. Taylor; Nanxue Yuan; Claudio Bruschini; Stefan T. Radev; Margarida M. Barroso; Andrew Tobin; Xavier Michalet; Edoardo Charbon; Daniele Faccio; Xavier Intes
err分享
err收藏
Lysine targeting covalent inhibitors of malarial kinase PfCLK3赖氨酸靶向的恶性疟原虫激酶PfCLK3共价抑制剂
errRSC Med. Chem.
IF3.6
err2025-08-14
err0
errOAAI
errSkye B. Brettell; Gillian Cann; Abbey Begen; Saumya Sharma; Amit Mahindra; Lauren V. Carruthers; Graeme Milligan; David J. Clarke; Andrew B. Tobin; Andrew G. Jamieson
err分享
err收藏
Biased constitutive signaling of the G protein-coupled receptor GPR35 suppresses gut barrier permeability
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2025-01-01
err0
errOAAI
errQuon, Tezz; Lin, Li-Chiung; Ganguly, Amlan; Hudson, Brian D.; Tobin, Andrew B.; Milligan, Graeme
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Targeting PfCLK3 with Covalent Inhibitors: A Novel Strategy for Malaria Treatment
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-10-23
err0
errOAAI
errBrettell, Skye B.; Janha, Omar; Begen, Abbey; Cann, Gillian; Sharma, Saumya; Olaniyan, Niniola; Yelland, Tamas; Hole, Alison J.; Alam, Benazir; Mayville, Emily; Gillespie, Ross; Capper, Michael; Fidock, David A.; Milligan, Graeme; Clarke, David J.; Tobin, Andrew B.; Jamieson, Andrew G.
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A golden age of muscarinic acetylcholine receptor modulation in neurological diseases
errNATURE REVIEWS DRUG DISCOVERY
IF101.8
err2024-08-14
err0
PREAI
errTobin, Andrew B.
err分享
err收藏
Phosphorylation bar-coding of free fatty acid receptor 2 is generated in a tissue-specific manner游离脂肪酸受体2的磷酸化条形码以组织特异性方式产生
errELIFE
IF0
err2023-12-12
err0
errOAAI
errBarki, Natasja; Jenkins, Laura; Marsango, Sara; Dedeo, Domonkos; Bolognini, Daniele; Dwomoh, Louis; Abdelmalik, Aisha M.; Nilsen, Margaret; Stoffels, Manon; Nagel, Falko; Schulz, Stefan; Tobin, Andrew B.; Milligan, Graeme
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err收藏
G protein-receptor kinases 5/6 are the key regulators of G protein-coupled receptor 35-arrestin interactions
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2023-10-01
err4
errOAAI
errGanguly, Amlan; Quon, Tezz; Jenkins, Laura; Joseph, Babu; Al-awar, Rima; Chevigne, Andy; Tobin, Andrew B.; Uehling, David E.; Hoffmann, Carsten; Drube, Julia; Milligan, Graeme
err分享
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Design, synthesis and evaluation of novel 2-phenyl-3-(1H-pyrazol-4-yl) pyridine positive allosteric modulators for the M4 mAChR
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2023-10-01
err1
PREAI
errJorg, Manuela; van der Westhuizen, Emma T.; Lu, Yao; Choy, K. H. Christopher; Shackleford, David M.; Khajehali, Elham; Tobin, Andrew B.; Thal, David M.; Capuano, Ben; Christopoulos, Arthur; Valant, Celine; Scammells, Peter J.
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Xanomeline displays concomitant orthosteric and allosteric binding modes at the M4 mAChRXanomeline在M4 mAChR处显示伴随的正构和变构结合模式
errNATURE COMMUNICATIONS
IF15.7
err2023-09-06
err10
errOAAI
errBurger, Wessel A. C.; Pham, Vi; Vuckovic, Ziva; Powers, Alexander S.; Mobbs, Jesse I.; Laloudakis, Yianni; Glukhova, Alisa; Wootten, Denise; Tobin, Andrew B.; Sexton, Patrick M.; Paul, Steven M.; Felder, Christian C.; Danev, Radostin; Dror, Ron O.; Christopoulos, Arthur; Valant, Celine; Thal, David M.
err分享
err收藏
A growing understanding of the role of muscarinic receptors in the molecular pathology and treatment of schizophrenia对毒蕈碱受体在精神分裂症的分子病理学和治疗中的作用的日益了解
errFRONTIERS IN CELLULAR NEUROSCIENCE
IF4
err2023-02-22
err18
errOAAI
errDean, Brian; Bakker, Geor; Ueda, Hiroki R.; Tobin, Andrew B.; Brown, Alastair; Kanaan, Richard A. A.
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err收藏
Opportunities and challenges for the development of M1 muscarinic receptor positive allosteric modulators in the treatment for neurocognitive deficits
errBRITISH JOURNAL OF PHARMACOLOGY
IF7.7
err2022-12-04
err11
PREAI
errNguyen, Huong T. M.; van der Westhuizen, Emma T.; Langmead, Christopher J.; Tobin, Andrew B.; Sexton, Patrick M.; Christopoulos, Arthur; Valant, Celine
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M1 muscarinic receptor activation reduces the molecular pathology and slows the progression of prion-mediated neurodegenerative disease
errSCIENCE SIGNALING
IF6.6
err2022-11-15
err10
errOAAI
errDwomoh, Louis; Rossi, Mario; Scarpa, Miriam; Khajehali, Elham; Molloy, Colin; Herzyk, Pawel; Mistry, Shailesh N.; Bottrill, Andrew R.; Sexton, Patrick M.; Christopoulos, Arthur; Conn, P. Jeffrey; Lindsley, Craig W.; Bradley, Sophie J.; Tobin, Andrew B.
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The M1 muscarinic receptor is present in situ as a ligand-regulated mixture of monomers and oligomeric complexes
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2022-06-07
err7
errOAAI
errMarsango, Sara; Jenkins, Laura; Pediani, John D.; Bradley, Sophie J.; Ward, Richard J.; Hesse, Sarah; Biener, Gabriel; Stoneman, Michael R.; Tobin, Andrew B.; Raicu, Valerica; Milligan, Graeme
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Selective phosphorylation of threonine residues defines GPR84-arrestin interactions of biased ligands
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2022-05-01
err17
errOAAI
errMarsango, Sara; Ward, Richard J.; Jenkins, Laura; Butcher, Adrian J.; Al Mahmud, Zobaer; Dwomoh, Louis; Nagel, Falko; Schulz, Stefan; Tikhonova, Irina G.; Tobin, Andrew B.; Milligan, Graeme
err分享
err收藏
Agonist-induced phosphorylation of orthologues of the orphan receptor GPR35 functions as an activation sensor
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2022-03-01
err19
errOAAI
errDivorty, Nina; Jenkins, Laura; Ganguly, Amlan; Butcher, Adrian J.; Hudson, Brian D.; Schulz, Stefan; Tobin, Andrew B.; Nicklin, Stuart A.; Milligan, Graeme
err分享
err收藏
Biased M1 muscarinic receptor mutant mice show accelerated progression of prion neurodegenerative disease偏向的M1毒蕈碱受体突变小鼠显示出病毒神经退行性疾病的加速进展
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2021-12-10
err15
errOAAI
errScarpa, Miriam; Molloy, Colin; Jenkins, Laura; Strellis, Bethany; Budgett, Rebecca F.; Hesse, Sarah; Dwomoh, Louis; Marsango, Sara; Tejeda, Gonzalo S.; Rossi, Mario; Ahmed, Zeshan; Milligan, Graeme; Hudson, Brian D.; Tobin, Andrew B.; Bradley, Sophie J.
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Identification of a Novel Allosteric Site at the M5 Muscarinic Acetylcholine Receptor
errACS CHEMICAL NEUROSCIENCE
IF3.9
err2021-08-05
err7
PREAI
errBurger, Wessel A. C.; Gentry, Patrick R.; Berizzi, Alice E.; Vuckovic, Ziva; van der Westhuizen, Emma T.; Thompson, Geoff; Yeasmin, Mahmuda; Lindsley, Craig W.; Sexton, Patrick M.; Langmead, Christopher J.; Tobin, Andrew B.; Christopoulos, Arthur; Valant, Celine; Thal, David M.
err分享
err收藏

研究方向

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合作学者
合作期刊
K
Kian Fan Chung
H 指数: 142 · 论文数: 1.6K
C
Christopher E. Brightling
H 指数: 131 · 论文数: 1.2K
F
Felipe F. Casanueva
H 指数: 121 · 论文数: 951
S
Stephen B. McMahon
H 指数: 109 · 论文数: 472
M
Michel Bouvier
H 指数: 108 · 论文数: 808
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