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M

Mark A. Dawson

University of Melbourne
H指数:55
被引数:1.8万

个人简介

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教育背景

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荣誉奖项

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The stress-sensing MARCH5 axis governs blood cancer apoptotic resilience via tractable protein–protein interactions

压力感应的MARCH5轴通过可调节的蛋白质-蛋白质相互作用调控血液癌症的凋亡抗性

Blood
IF23.1
2026-09-110
PRE
Thomas E. Lew; Mark F. van Delft; Luuk Heitink; Simon A. Cobbold; Christine A. White; Jason A. R. Bong; Philip H. Hittmeyer; Amelia H. Zhu; Vineet Vaibhav; Jumana Yousef; Laura Dagley; Christopher D. Riffkin; Angela Georgiou; Adrienne Hilton; Allan S. Huang; Yin Yuan; Miles B. Horton; Mark A. Dawson; Andrew W. Roberts; David C. S. Huang
Rb-driven transcription limits its tumour-suppressive effects in breast cancer

Rb驱动的转录限制其在乳腺癌中的肿瘤抑制作用

Nature
IF48.5
2026-08-120
OA
April C. Watt; Antonio Ahn; Catherine Blyth; Julia R. Dixon-Douglas; Krutika Ambani; Rhiannon Coulson; Michael Taylor; Keefe T. Chan; Catherine Dietrich; Brendan E. Russ; Susanne Ramm; Christabella A. Mahendra; Kun-Hui Lu; Nichelle Pires; Jesus Garcia-Sannicolas; Olivia Voulgaris; Sheena Nunag; Ching-Seng Ang; Mark A. Dawson; Elgene Lim; Monica Arnedos; Sarat Chandarlapaty; Fabrice André; Shom Goel
Mosaic chromosomal alterations are suppressed in older adults with HIV

HIV感染者老年人中嵌合染色体异常受到抑制

Communications Biology
IF5.1
2026-07-210
OAAI
Kiarash Behrouzfar; Win Min Han; Rashindrie Perera; Jason Li; Katherine E. Scull; Kerryn Howlett; Mark Bloch; David A. Baker; Beng Eu; Ellen Bowden-Reid; Don E. Smith; Jennifer F. Hoy; Ian Woolley; Robert Finlayson; David J. Templeton; Gail V. Matthews; Jane Costello; Mark A. Dawson; Sarah-Jane Dawson; Mark N. Polizzotto; Kathy Petoumenos; Nila J. Dharan; Paul Yeh
SUMOylation enhances DNMT1 function to repress mega-intergenic RNAs and viral mimicry
Nature Genetics
IF29
2026-07-210
PRE
Brian J. Liddicoat; Jesse J. Balic; Wendy Jia; Andrea Gillespie; Andrew B. Das; Laura Scolamiero; Naiara G. Bediaga; Yih-Chih Chan; Christa van der Maarel; Andrew A. Guirguis; Kelsy Prest; Oliver J. Sinclair; Laure Talarmain; Cassandra Litchfield; Enid Y. N. Lam; Sebastian Hollizeck; John R. Horton; Benjamin Kroeger; Tao Wang; Francesca Zappacosta; Roland S. Annan; Rab K. Prinjha; Melissa B. Pappalardi; Michael T. McCabe; Ching-Seng Ang; Matthew S. Graus; Mathias Francois; Kieran F. Harvey; Sarah-Jane Dawson; Xiaodong Cheng; Mark A. Dawson
Antigen reactivity defines tissue-resident memory and exhausted T cells in tumors

抗原反应性定义了肿瘤中的组织驻留记忆T细胞和耗竭T细胞。

Nature Immunology
IF27.6
2025-12-290
OAAI
Thomas N. Burn; Jan Schröder; Luke C. Gandolfo; Maleika Osman; Elanor N. Wainwright; Enid Y. N. Lam; Keely M. McDonald; Rachel B. Evans; Shihan Li; Daniel Rawlinson; Lachlan Dryburgh; Ali Zaid; Zoltan Maliga; Dominick Schienstock; Philippa Meiser; Hyun Jae Lee; Hongjin Lai; Marcela L. Moreira; Pirooz Zareie; Louis H-Y. Lee; Lutfi Huq; Susan N. Christo; Justine J. W. Seow; Keith A. Ching; Stéphane M. Guillaume; Kathy Knezevic; Simone L. Park; Maximilien Evrard; Jason Waithman; Thomas Gebhardt; Scott N. Mueller; Georgina E. Riddiough; Marcos V. Perini; Simon C. H. Tsao; Terence P. Speed; Peter K. Sorger; Sherene Loi; Francis R. Carbone; Stephanie Gras; Timothy S. Fisher; Bas J. Baaten; Mark A. Dawson; Laura K. Mackay
Acute Resistance to BET Inhibitors Remodels Compensatory Transcriptional Programs Via p300 Co-Activation

急性对BET抑制剂的耐药性通过p300协同激活重塑补偿性转录程序

BLOOD
IF23.1
2024-11-050
PRE
Shah, Viral; Giotopoulos, George; Osaki, Hikari; Meyerhoefer, Markus; Meduri, Eshwar; Gallego-Crespo, Aaron; Behrendt, Malte Andreas; Saura-Panella, Maria; Schubert, Benedict; Yun, Haiyang; Horton, Sarah J.; Singh, Shuchi Agrawal; Haehnel, Patricia S.; Basheer, Faisal; Lugo, Dave; Kuehn, Michael; Guezguez, Borhane; Theobald, Matthias; Kindler, Thomas; Gallipoli, Paolo; Yeh, Paul; Dawson, Mark A.; Prinjha, Rab; Huntly, Brian J. P.; Sasca, Daniel
CRISPR-Cas9 screening identifies an IRF1-SOCS1-mediated negative feedback loop that limits CXCL9 expression and antitumor immunity (vol 42, 113014, 2023)
CELL REPORTS
IF6.9
2024-02-010
OA
House, Imran G.; Derrick, Emily B.; Sek, Kevin; Chen, Amanda X. Y.; Li, Jasmine; Lai, Junyun; Todd, Kirsten L.; Munoz, Isabelle; Michie, Jessica; Chan, Cheok Weng; Huang, Yu-Kuan; Chan, Jack D.; Petley, Emma V.; Tong, Junming; Nguyen, Datminh; Engel, Sven; Savas, Peter; Hogg, Simon J.; Vervoort, Stephin J.; Kearney, Conor J.; Burr, Marian L.; Lam, Enid Y. N.; Gilan, Omer; Bedoui, Sammy; Johnstone, Ricky W.; Dawson, Mark A.; Loi, Sherene; Darcy, Phillip K.; Beavis, Paul A.
Discovery of a highly potent, selective, orally bioavailable inhibitor of KAT6A/B histone acetyltransferases with efficacy against KAT6A-high ER+ breast cancer

发现一种高效，选择性，口服生物利用度的KAT6A/B组蛋白乙酰转移酶抑制剂，对KAT6A-high ER乳腺癌有效

CELL CHEMICAL BIOLOGY
IF7.2
2023-10-0121
OAAI
Sharma, Shikhar; Chung, Chi-Yeh; Uryu, Sean; Petrovic, Jelena; Cao, Joan; Rickard, Amanda; Nady, Nataliya; Greasley, Samantha; Johnson, Eric; Brodsky, Oleg; Khan, Showkhin; Wang, Hui; Wang, Zhenxiong; Zhang, Yong; Tsaparikos, Konstantinos; Chen, Lei; Mazurek, Anthony; Lapek, John; Kung, Pei-Pei; Sutton, Scott; Richardson, Paul F.; Greenwald, Eric C.; Yamazaki, Shinji; Jones, Rhys; Maegley, Karen A.; Bingham, Patrick; Lam, Hieu; Stupple, Alexandra E.; Kamal, Aileen; Chueh, Anderly; Cuzzupe, Anthony; Morrow, Benjamin J.; Ren, Bin; Carrasco-Pozo, Catalina; Tan, Chin Wee; Bhuva, Dharmesh D.; Allan, Elizabeth; Surgenor, Elliot; Vaillant, Francois; Pehlivanoglu, Havva; Falk, Hendrik; Whittle, James R.; Newman, Janet; Cursons, Joseph; Doherty, Judy P.; White, Karen L.; Macpherson, Laura; Devlin, Mark; Dennis, Matthew L.; Hattarki, Meghan K.; De Silva, Melanie; Camerino, Michelle A.; Butler, Miriam S.; Dolezal, Olan; Pilling, Patricia; Foitzik, Richard; Stupple, Paul A.; Lagiakos, H. Rachel; Walker, Scott R.; Hediyeh-Zadeh, Soroor; Nuttall, Stewart; Spall, Sukhdeep; Charman, Susan A.; Connor, Theresa; Peat, Thomas S.; Avery, Vicky M.; Bozikis, Ylva E.; Yang, Yuqing; Zhang, Ming; Monahan, Brendon J.; Voss, Anne K.; Street, Ian P.; Dawson, Sarah-Jane; Dawson, Mark A.; Lindeman, Geoffrey J.; Davis, Melissa J.; Visvader, Jane E.; Paul, Thomas A.
Inhibition of METTL3 Results in a Cell-Intrinsic Interferon Response That Enhances Antitumor Immunity

抑制METTL3导致细胞内在的干扰素反应，从而增强抗肿瘤免疫力

CANCER DISCOVERY
IF33.3
2023-08-0729
PRE
Guirguis, Andrew A.; Ofir-Rosenfeld, Yaara; Knezevic, Kathy; Blackaby, Wesley; Hardick, David; Chan, Yih-Chih; Motazedian, Ali; Gillespie, Andrea; Vassiliadis, Dane; Lam, Enid Y. N.; Tran, Kevin; Andrews, Byron; Harbour, Michael E.; Vasiliauskaite, Lina; Saunders, Claire J.; Tsagkogeorga, Georgia; Azevedo, Aleksandra; Obacz, Joanna; Pilka, Ewa S.; Carkill, Marie; Macpherson, Laura; Wainwright, Elanor N.; Liddicoat, Brian; Blyth, Benjamin J.; Albertella, Mark R.; Rausch, Oliver; Dawson, Mark A.
CRISPR-Cas9 screening identifies an IRF1-SOCS1-mediated negative feedback loop that limits CXCL9 expression and antitumor immunity

CRISPR-Cas9筛选确定了限制CXCL9表达和抗肿瘤免疫的IRF1-SOCS1-mediated负反馈回路

CELL REPORTS
IF6.9
2023-08-016
OA
House, Imran G.; Derrick, Emily B.; Sek, Kevin; Chen, Amanda X. Y.; Li, Jasmine; Lai, Junyun; Todd, Kirsten L.; Munoz, Isabelle; Michie, Jessica; Chan, Cheok Weng; Huang, Yu-Kuan; Chan, Jack D.; Petley, Emma, V; Tong, Junming; Nguyen, DatMinh; Engel, Sven; Savas, Peter; Hogg, Simon J.; Vervoort, Stephin J.; Kearney, Conor J.; Burr, Marian L.; Lam, Enid Y. N.; Gilan, Omer; Bedoui, Sammy; Johnstone, Ricky W.; Dawson, Mark A.; Loi, Sherene; Darcy, Phillip K.; Beavis, Paul A.

研究方向

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E
Enid Y.N. Lam
H 指数:27论文数:127被引数:5,713
S
Sarah‐Jane Dawson
H 指数:57论文数:254被引数:2.3万
O
Omer Gilan
H 指数:21论文数:42被引数:4,841
Y
Yih-Chih Chan
H 指数:17论文数:142被引数:2,991
C
Charles C. Bell
H 指数:18论文数:35被引数:2,984
R
Rab K. Prinjha
H 指数:64论文数:229被引数:1.9万
D
Dane Vassiliadis
H 指数:12论文数:142被引数:1,897
R
Ricky W. Johnstone
H 指数:96论文数:780被引数:3.8万
A
Andrew J. Bannister
H 指数:60论文数:133被引数:3.2万
T
Tony Kouzarides
H 指数:109论文数:248被引数:7.5万